Interactor 1: ODPA (P08559)
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial (EC 1.2.4.1) (PDHE1-A type I)
Gene: PDHA1

Interactor 2: DHTK1 (Q96HY7)
2-oxoadipate dehydrogenase complex component E1 (E1a) (OADC-E1) (OADH-E1) (EC 1.2.4.-) (2-oxoadipate dehydrogenase, mitochondrial) (Alpha-ketoadipate dehydrogenase) (Alpha-KADH-E1) (Dehydrogenase E1 and transketolase domain-containing protein 1) (Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial)
Gene: DHTKD1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 34079125
Identification Methods proximity labelling technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains E1_dh~E1_dh, E1_dh~OxoGdeHyase_C, E1_dh~Transket_pyr
Common GO terms GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0006099 - tricarboxylic acid cycle
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 390
Hs

1 919
+ Hs
+ Hs
+ Sc
+ At
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024