HitPredict

Interactor 1: MET (P08581)
Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met)
Gene: MET

Interactor 2: CALX (P27824)
Calnexin (IP90) (Major histocompatibility complex class I antigen-binding protein p88) (p90)
Gene: CANX

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35384245, 36736316
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1390 Hs			1 592
+	Hs
		161004 MET_HUMAN (1-1390): 0: 1283: 100.00		CLGN_HUMAN (11-546): 0: 652: 59.85
+	Hs
		441437 MET_HUMAN (1-1390): 0: 1283: 100.00		CALR_HUMAN (67-470): 1.19e-141: 418: 38.33
+	Hs
		654090 EPHA3_HUMAN (584-1379): 1.09e-179: 561: 18.13		CALX_HUMAN (1-592): 0: 786: 100.00
+	Hs
		654184 PLXA3_HUMAN (381-1019): 8.58e-111: 388: 17.82		CALX_HUMAN (1-592): 0: 786: 100.00
+	Hs
		601462 FGFR2_HUMAN (1029-1379): 3.01e-105: 355: 33.15		CALX_HUMAN (1-592): 0: 786: 100.00
+	Hs
		654101 UFO_HUMAN (1078-1333): 5.27e-66: 243: 45.90		CALX_HUMAN (1-592): 0: 786: 100.00
+	Hs
		654279 TYRO3_HUMAN (1053-1341): 6.19e-65: 240: 41.67		CALX_HUMAN (1-592): 0: 786: 100.00
+	Hs
		435545 IGF1R_HUMAN (1084-1337): 2.07e-56: 217: 42.16		CALX_HUMAN (1-592): 0: 786: 100.00
+	Hs
		411305 INSR_HUMAN (1084-1335): 3.87e-55: 213: 42.11		CALX_HUMAN (1-592): 0: 786: 100.00
+	Hs
		253453 PLXA2_HUMAN (380-1069): 6.87e-53: 206: 18.27		CALX_HUMAN (1-592): 0: 786: 100.00
+	Hs
		161056 TYRO3_HUMAN (1053-1341): 6.19e-65: 240: 41.67		CLGN_HUMAN (11-546): 0: 652: 59.85
+	Hs
		161003 IGF1R_HUMAN (1084-1337): 2.07e-56: 217: 42.16		CLGN_HUMAN (11-546): 0: 652: 59.85
+	Hs
		160999 INSR_HUMAN (1084-1335): 3.87e-55: 213: 42.11		CLGN_HUMAN (11-546): 0: 652: 59.85
+	Hs
		653574 MERTK_HUMAN (1057-1385): 1.56e-67: 249: 40.88		CALR_HUMAN (67-470): 1.19e-141: 418: 38.33
+	Hs
		653493 UFO_HUMAN (1078-1333): 5.27e-66: 243: 45.90		CALR_HUMAN (67-470): 1.19e-141: 418: 38.33
+	Rn
		544766 INSR_RAT (1084-1335): 3.22e-52: 204: 40.98		CALR_RAT (67-470): 7.8e-147: 431: 37.35