Protein: HDBP1
Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 (GPI-HBP1) (GPI-anchored HDL-binding protein 1) (High density lipoprotein-binding protein 1)

Gene: HDBP1, GPIHBP1
Organism: Homo sapiens
Interactions: 158
UniProt ID: Q8IV16

Gene Ontology (top 5):
GO:0005576 - extracellular region
GO:0005886 - plasma membrane
GO:0006886 - intracellular protein transport
GO:0008289 - lipid binding
GO:0009897 - external side of plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

449527

LIPL
Lipoprotein lipase

2

0

Small-scale

0.614

High

161055

ADA10
Disintegrin and metalloproteinase domain-containing protein 10

2

6

High-throughput

0.601

High

324009

CSTN1
Calsyntenin-1

2

2

High-throughput

0.601

High

465566

IGF1R
Insulin-like growth factor 1 receptor

2

2

High-throughput

0.601

High

472091

MET
Hepatocyte growth factor receptor

2

6

High-throughput

0.601

High

551875

CO6A2

2

1

High-throughput

0.601

High

1308287

DCBD2
Discoidin, CUB and LCCL domain-containing protein 2

2

3

High-throughput

0.601

High

327112

NXPH4
Neurexophilin-4

2

0

High-throughput

0.576

High

1308279

TTC17
Tetratricopeptide repeat protein 17

2

0

High-throughput

0.576

High

1308293

CHID1
Chitinase domain-containing protein 1

2

0

High-throughput

0.576

High

1131472

MBTP1
Membrane-bound transcription factor site-1 protease

2

2

High-throughput

0.549

High

1286278

GALT7
N-acetylgalactosaminyltransferase 7

2

4

High-throughput

0.549

High

1308302

UGGG2
UDP-glucose:glycoprotein glucosyltransferase 2

2

2

High-throughput

0.549

High

136621

MANBA
Beta-mannosidase

1

1

High-throughput

0.536

High

183275

LAMA5
Laminin subunit alpha-5

1

4

High-throughput

0.536

High

269684

PLXA2
Plexin-A2

1

3

High-throughput

0.536

High

270216

ADA11
Disintegrin and metalloproteinase domain-containing protein 11

1

5

High-throughput

0.536

High

337272

ATS2
A disintegrin and metalloproteinase with thrombospondin motifs 2

1

4

High-throughput

0.536

High

337535

LARG1
Xylosyl- and glucuronyltransferase LARGE1

1

1

High-throughput

0.536

High

439775

INSR
Insulin receptor

1

2

High-throughput

0.536

High

441438

CHLE
Cholinesterase

1

2

High-throughput

0.536

High

467838

BGLR
Beta-glucuronidase

1

1

High-throughput

0.536

High

535863

LAMC1
Laminin subunit gamma-1

1

2

High-throughput

0.536

High

611745

BMP7
Bone morphogenetic protein 7

1

2

High-throughput

0.536

High

648580

FGFR4
Fibroblast growth factor receptor 4

1

1

High-throughput

0.536

High

650280

FGFR3
Fibroblast growth factor receptor 3

1

1

High-throughput

0.536

High

709069

PCSK6
Proprotein convertase subtilisin/kexin type 6

1

5

High-throughput

0.536

High

719726

HLAF
HLA class I histocompatibility antigen, alpha chain F

1

1

High-throughput

0.536

High

756566

GALNS
N-acetylgalactosamine-6-sulfatase

1

3

High-throughput

0.536

High

907919

PLXA3
Plexin-A3

1

3

High-throughput

0.536

High

922831

ITA8
Integrin alpha-8 [Cleaved into: Integrin alpha-8 heavy chain; Integrin alpha-8 light chain]

1

2

High-throughput

0.536

High

937411

LAMB2
Laminin subunit beta-2

1

2

High-throughput

0.536

High

1116726

ITA7
Integrin alpha-7 [Cleaved into: Integrin alpha-7 heavy chain; Integrin alpha-7 light chain; Integrin alpha-7 70 kDa form]

1

2

High-throughput

0.536

High

1144630

PTPRK
Receptor-type tyrosine-protein phosphatase kappa

1

1

High-throughput

0.536

High

1177230

MICA
MHC class I polypeptide-related sequence A

1

2

High-throughput

0.536

High

1201818

SDK2
Protein sidekick-2

1

1

High-throughput

0.536

High

1213208

AGRF1
Adhesion G-protein coupled receptor F1

1

1

High-throughput

0.536

High

1248911

ARSK
Arylsulfatase K

1

3

High-throughput

0.536

High

1294358

FRAS1
Extracellular matrix organizing protein FRAS1

1

5

High-throughput

0.536

High

1308258

SULF2
Extracellular sulfatase Sulf-2

1

3

High-throughput

0.536

High

1308259

SULF1
Extracellular sulfatase Sulf-1

1

3

High-throughput

0.536

High

1308263

VWDE
von Willebrand factor D and EGF domain-containing protein

1

1

High-throughput

0.536

High

1308264

NLGN1
Neuroligin-1

1

2

High-throughput

0.536

High

1308267

NLGN2
Neuroligin-2

1

2

High-throughput

0.536

High

1308270

ATS17
A disintegrin and metalloproteinase with thrombospondin motifs 17

1

4

High-throughput

0.536

High

1308271

AGRV1
Adhesion G-protein coupled receptor V1

1

3

High-throughput

0.536

High

1308274

PTPRU
Receptor-type tyrosine-protein phosphatase U

1

1

High-throughput

0.536

High

1308275

PCSK5
Proprotein convertase subtilisin/kexin type 5

1

4

High-throughput

0.536

High

1308277

HMR1
Major histocompatibility complex class I-related protein 1

1

1

High-throughput

0.536

High

1308295

CNTP3
Contactin-associated protein-like 3

1

1

High-throughput

0.536

High

1308305

ADA22
Disintegrin and metalloproteinase domain-containing protein 22

1

4

High-throughput

0.536

High

1308313

ATS7
A disintegrin and metalloproteinase with thrombospondin motifs 7

1

5

High-throughput

0.536

High

230984

TYOBP
TYRO protein tyrosine kinase-binding protein

1

0

High-throughput

0.513

High

274893

LRP5
Low-density lipoprotein receptor-related protein 5

1

0

High-throughput

0.513

High

341329

ECEL1
Endothelin-converting enzyme-like 1

1

0

High-throughput

0.513

High

350720

NOE2
Noelin-2

1

0

High-throughput

0.513

High

377333

PAHO
Pancreatic polypeptide prohormone

1

0

High-throughput

0.513

High

472188

TRFM
Melanotransferrin

1

0

High-throughput

0.513

High

562740

BMP1
Bone morphogenetic protein 1

1

0

High-throughput

0.513

High

599120

CBPE
Carboxypeptidase E

1

0

High-throughput

0.513

High

846822

BTD
Biotinidase

1

0

High-throughput

0.513

High

870825

GLRB
Glycine receptor subunit beta

1

0

High-throughput

0.513

High

906312

GPC3
Glypican-3

1

0

High-throughput

0.513

High

1084050

SIA4C
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4

1

0

High-throughput

0.513

High

1211293

DNLZ
DNL-type zinc finger protein

1

0

High-throughput

0.513

High

1212670

GT253
Inactive glycosyltransferase 25 family member 3

1

0

High-throughput

0.513

High

1248864

GLB1L
Beta-galactosidase-1-like protein

1

0

High-throughput

0.513

High

1308269

CERK1
Ceramide kinase

1

0

High-throughput

0.513

High

1308273

PGTA
Geranylgeranyl transferase type-2 subunit alpha

1

0

High-throughput

0.513

High

1308276

EXT2
Exostosin-2

1

0

High-throughput

0.513

High

1308278

NXPE3
NXPE family member 3

1

0

High-throughput

0.513

High

1308281

CTHR1
Collagen triple helix repeat-containing protein 1

1

0

High-throughput

0.513

High

1308282

I17RA
Interleukin-17 receptor A

1

0

High-throughput

0.513

High

1308290

SEM3C
Semaphorin-3C

1

0

High-throughput

0.513

High

1308294

GTPB2
GTP-binding protein 2

1

0

High-throughput

0.513

High

1308299

PLAC1
Placenta-specific protein 1

1

0

High-throughput

0.513

High

1308304

KCMF1
E3 ubiquitin-protein ligase KCMF1

1

0

High-throughput

0.513

High

615219

IL1RA
Interleukin-1 receptor antagonist protein

1

0

High-throughput

0.493

High

617319

ATF6A
Cyclic AMP-dependent transcription factor ATF-6 alpha

1

1

High-throughput

0.489

High

760798

BMP8B
Bone morphogenetic protein 8B

1

2

High-throughput

0.489

High

885486

MA2A2
Alpha-mannosidase 2x

1

1

High-throughput

0.489

High

1038198

GCNT1
Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase

1

1

High-throughput

0.489

High

1085676

TBL3
Transducin beta-like protein 3

1

1

High-throughput

0.489

High

1162138

MA2A1
Alpha-mannosidase 2

1

1

High-throughput

0.489

High

1243276

GLT18
Polypeptide N-acetylgalactosaminyltransferase 18

1

4

High-throughput

0.489

High

1248511

SUSD1
Sushi domain-containing protein 1

1

2

High-throughput

0.489

High

1249893

CREL2
Protein disulfide isomerase CRELD2

1

2

High-throughput

0.489

High

1279475

BMP8A
Bone morphogenetic protein 8A

1

2

High-throughput

0.489

High

1307157

GLT13
Polypeptide N-acetylgalactosaminyltransferase 13

1

4

High-throughput

0.489

High

1308260

GLT12
Polypeptide N-acetylgalactosaminyltransferase 12

1

4

High-throughput

0.489

High

1308261

CHSS2
Chondroitin sulfate synthase 2

1

1

High-throughput

0.489

High

1308265

LARG2
Xylosyl- and glucuronyltransferase LARGE2

1

1

High-throughput

0.489

High

1308283

GLT14
Polypeptide N-acetylgalactosaminyltransferase 14

1

4

High-throughput

0.489

High

1308289

ATF6B
Cyclic AMP-dependent transcription factor ATF-6 beta

1

1

High-throughput

0.489

High

1308291

CSTN3
Calsyntenin-3

1

3

High-throughput

0.489

High

1308292

EDEM2
ER degradation-enhancing alpha-mannosidase-like protein 2

1

1

High-throughput

0.489

High

1308296

EDEM3
ER degradation-enhancing alpha-mannosidase-like protein 3

1

1

High-throughput

0.489

High

1308297

XYLT2
Xylosyltransferase 2

1

1

High-throughput

0.489

High

1308306

CHPF2
Chondroitin sulfate glucuronyltransferase

1

1

High-throughput

0.489

High

551802

CO6A1

1

1

High-throughput

0.445

High

592673

ITB4
Integrin beta-4

1

1

High-throughput

0.445

High

626966

FST
Follistatin

1

1

High-throughput

0.445

High

654988

ITA6
Integrin alpha-6

1

2

High-throughput

0.445

High

731928

L1CAM
Neural cell adhesion molecule L1

1

1

High-throughput

0.445

High

946246

ATS12
A disintegrin and metalloproteinase with thrombospondin motifs 12

1

4

High-throughput

0.445

High

1087063

FSTL1
Follistatin-related protein 1

1

1

High-throughput

0.445

High

1127576

FAT1
Protocadherin Fat 1

1

1

High-throughput

0.445

High

1164052

PTPRN
Receptor-type tyrosine-protein phosphatase-like N

1

2

High-throughput

0.445

High

1250376

PCD23
Protocadherin-23

1

1

High-throughput

0.445

High

1308310

PLXA1
Plexin-A1

1

4

High-throughput

0.445

High

441494

AGAL
Alpha-galactosidase A

1

0

High-throughput

0.426

High

458700

SAP
Prosaposin

1

0

High-throughput

0.426

High

633856

MPRD
Cation-dependent mannose-6-phosphate receptor

1

0

High-throughput

0.426

High

928791

CA2D1
Voltage-dependent calcium channel subunit alpha-2/delta-1

1

0

High-throughput

0.426

High

937588

CAD13
Cadherin-13

1

0

High-throughput

0.426

High

1124172

IL27B
Interleukin-27 subunit beta

1

0

High-throughput

0.426

High

1131450

RFTN1
Raftlin

1

0

High-throughput

0.426

High

1308262

RPTOR
Regulatory-associated protein of mTOR

1

1

High-throughput

0.407

High

1308286

CNT3B
Contactin-associated protein-like 3B

1

2

High-throughput

0.407

High

1228387

SE1L3
Protein sel-1 homolog 3

2

0

High-throughput

0.313

High

1308303

SELN
Selenoprotein N

2

0

High-throughput

0.313

High

1308315

LOXL2
Lysyl oxidase homolog 2

2

0

High-throughput

0.313

High

107444

F8WC89
SAC3 domain containing 1

1

0

High-throughput

0.279

Low

168548

UB2L6
Ubiquitin/ISG15-conjugating enzyme E2 L6

1

0

High-throughput

0.279

Low

281226

CDC45
Cell division control protein 45 homolog

1

0

High-throughput

0.279

Low

302260

STC2
Stanniocalcin-2

1

0

High-throughput

0.279

Low

317461

GFPT2
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2

1

0

High-throughput

0.279

Low

322151

GLCE
D-glucuronyl C5-epimerase

1

0

High-throughput

0.279

Low

642101

ODBB
2-oxoisovalerate dehydrogenase subunit beta, mitochondrial

1

0

High-throughput

0.279

Low

771671

IDUA
Alpha-L-iduronidase

1

0

High-throughput

0.279

Low

884668

SYHM
Histidine--tRNA ligase, mitochondrial

1

0

High-throughput

0.279

Low

1127923

PDIA5
Protein disulfide-isomerase A5

1

0

High-throughput

0.279

Low

1154246

NPTX1
Neuronal pentraxin-1

1

0

High-throughput

0.279

Low

1179105

TECT1
Tectonic-1

1

0

High-throughput

0.279

Low

1191871

TBB8
Tubulin beta-8 chain

1

0

High-throughput

0.279

Low

1208451

EOGT
EGF domain-specific O-linked N-acetylglucosamine transferase

1

0

High-throughput

0.279

Low

1214097

DIK1A
Divergent protein kinase domain 1A

1

0

High-throughput

0.279

Low

1248332

PLGT2
Protein O-glucosyltransferase 2

1

0

High-throughput

0.279

Low

1291932

WDR5B
WD repeat-containing protein 5B

1

0

High-throughput

0.279

Low

1308266

TTC13
Tetratricopeptide repeat protein 13

1

0

High-throughput

0.279

Low

1308268

RFESD
Rieske domain-containing protein

1

0

High-throughput

0.279

Low

1308272

TM131
Transmembrane protein 131

1

0

High-throughput

0.279

Low

1308280

PBIP1
Pre-B-cell leukemia transcription factor-interacting protein 1

1

0

High-throughput

0.279

Low

1308284

DUS3L
tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like

1

0

High-throughput

0.279

Low

1308285

MYO19
Unconventional myosin-XIX

1

0

High-throughput

0.279

Low

1308298

TOR3A
Torsin-3A

1

0

High-throughput

0.279

Low

1308301

FKB14
Peptidyl-prolyl cis-trans isomerase FKBP14

1

0

High-throughput

0.279

Low

1308307

TXD16
Thioredoxin domain-containing protein 16

1

0

High-throughput

0.279

Low

1308309

NDUAC
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12

1

0

High-throughput

0.279

Low

1308311

GNPTG
N-acetylglucosamine-1-phosphotransferase subunit gamma

1

0

High-throughput

0.279

Low

1308312

NOCT
Nocturnin

1

0

High-throughput

0.279

Low

1308314

PTH2
Peptidyl-tRNA hydrolase 2, mitochondrial

1

0

High-throughput

0.279

Low

843739

HD
Huntingtin

1

0

High-throughput

0.268

Low

840076

CASP3
Caspase-3

1

0

High-throughput

0.232

Low

1308257

FXRD2
FAD-dependent oxidoreductase domain-containing protein 2

1

0

High-throughput

0.232

Low

1308288

MCCA
Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial

1

0

High-throughput

0.232

Low

1308300

TYW1
S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1

1

0

High-throughput

0.232

Low

1308308

DKK3
Dickkopf-related protein 3

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025