Protein: NLGN2
Neuroligin-2

Gene: NLGN2
Organism: Homo sapiens
Interactions: 62
UniProt ID: Q8NFZ4

Gene Ontology (top 5):
GO:0001966 - thigmotaxis
GO:0002087 - regulation of respiratory gaseous exchange by nervous system process
GO:0005886 - plasma membrane
GO:0007158 - neuron cell-cell adhesion
GO:0007416 - synapse assembly

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1339612

NLGN3
Neuroligin-3

2

14

High-throughput

0.811

High

593445

PGFRA
Platelet-derived growth factor receptor alpha

1

2

High-throughput

0.691

High

1339615

BTNL2
Butyrophilin-like protein 2

1

2

High-throughput

0.691

High

316533

B3GA3
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3

4

4

High-throughput

0.691

High

946279

NRX1B
Neurexin-1-beta

1

13

Small-scale

0.647

High

946294

NRX2B
Neurexin-2-beta

1

13

Small-scale

0.647

High

1339618

NRX3A
Neurexin-3

1

17

Small-scale

0.647

High

1219211

SUSD4
Sushi domain-containing protein 4

3

0

High-throughput

0.638

High

1339418

MDGA1
MAM domain-containing glycosylphosphatidylinositol anchor protein 1

1

0

Small-scale

0.614

High

533720

CLUS
Clusterin

2

0

High-throughput

0.602

High

855356

5HT3A
5-hydroxytryptamine receptor 3A

2

0

High-throughput

0.602

High

250122

ADCY9
Adenylate cyclase type 9

2

1

High-throughput

0.601

High

774508

BASI
Basigin

1

0

High-throughput

0.586

High

1339602

SIA8D
CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase

2

1

High-throughput

0.574

High

380459

DQA1
HLA class II histocompatibility antigen, DQ alpha 1 chain

1

2

High-throughput

0.536

High

388730

C1QB
Complement C1q subcomponent subunit B

1

4

High-throughput

0.536

High

520931

HLAC
HLA class I histocompatibility antigen, C alpha chain

1

1

High-throughput

0.536

High

607392

HLAG
HLA class I histocompatibility antigen, alpha chain G

1

1

High-throughput

0.536

High

634786

GRAH
Granzyme H

1

1

High-throughput

0.536

High

664068

PRTN3
Myeloblastin

1

1

High-throughput

0.536

High

705977

CD1B
T-cell surface glycoprotein CD1b

1

2

High-throughput

0.536

High

761266

RYK
Tyrosine-protein kinase RYK

1

1

High-throughput

0.536

High

1308267

HDBP1
Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1

1

2

High-throughput

0.536

High

1339617

TNF18
Tumor necrosis factor ligand superfamily member 18

1

1

High-throughput

0.536

High

64373

CDHR4
Cadherin-related family member 4

1

0

High-throughput

0.513

High

139272

UPK2
Uroplakin-2

1

0

High-throughput

0.513

High

341339

ECEL1
Endothelin-converting enzyme-like 1

1

0

High-throughput

0.513

High

506880

CFC1
Cryptic protein

1

0

High-throughput

0.513

High

688596

NKG2A
NKG2-A/NKG2-B type II integral membrane protein

1

0

High-throughput

0.513

High

755415

MA1A1
Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA

1

0

High-throughput

0.513

High

1034779

NAAA
N-acylethanolamine-hydrolyzing acid amidase

1

0

High-throughput

0.513

High

1273250

HS2ST
Heparan sulfate 2-O-sulfotransferase 1

1

0

High-throughput

0.513

High

1339604

T106A
Transmembrane protein 106A

1

0

High-throughput

0.513

High

1339605

ASIC4
Acid-sensing ion channel 4

1

0

High-throughput

0.513

High

191453

SIA8E
Alpha-2,8-sialyltransferase 8E

1

1

High-throughput

0.489

High

416634

REL1
Prorelaxin H1 [Cleaved into: Relaxin B chain; Relaxin A chain]

1

1

High-throughput

0.489

High

1204560

NMS
Neuromedin-S

1

1

High-throughput

0.489

High

1339607

CST11
Cystatin-11

1

1

High-throughput

0.489

High

1339610

B3GA2
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2

1

4

High-throughput

0.489

High

1006086

DLG4
Disks large homolog 4

1

19

Small-scale

0.481

High

1152414

DLG2
Disks large homolog 2

1

19

Small-scale

0.481

High

1339603

DLG3
Disks large homolog 3

1

19

Small-scale

0.481

High

1339613

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

4

High-throughput

0.479

High

1339609

SEM4B
Semaphorin-4B

1

2

High-throughput

0.445

High

1339606

SNX27
Sorting nexin-27

1

11

High-throughput

0.437

High

1242875

S39A4
Zinc transporter ZIP4

1

0

High-throughput

0.426

High

1288898

RIMS1
Regulating synaptic membrane exocytosis protein 1

1

0

High-throughput

0.426

High

1339611

EVA1B
Protein eva-1 homolog B

1

0

High-throughput

0.426

High

597806

CRIS2
Cysteine-rich secretory protein 2

2

0

High-throughput

0.328

High

1278867

LYZL2
Lysozyme-like protein 2

2

0

High-throughput

0.328

High

1322481

TTC5
Tetratricopeptide repeat protein 5

2

0

High-throughput

0.328

High

548072

PSPC
Surfactant protein C

1

0

High-throughput

0.279

Low

647387

IDS
Iduronate 2-sulfatase

1

0

High-throughput

0.279

Low

880041

DNSL1
Deoxyribonuclease-1-like 1

1

0

High-throughput

0.279

Low

1160422

TAZ
Tafazzin

1

0

High-throughput

0.279

Low

1181047

DB135
Beta-defensin 135

1

0

High-throughput

0.279

Low

1293619

DYR2
Dihydrofolate reductase 2, mitochondrial

1

0

High-throughput

0.279

Low

1325168

TAFA2
Chemokine-like protein TAFA-2

1

0

High-throughput

0.279

Low

1339601

PATE1
Prostate and testis expressed protein 1

1

0

High-throughput

0.279

Low

1339608

UD17
UDP-glucuronosyltransferase 1A7

1

0

High-throughput

0.279

Low

1339614

DNJB9
DnaJ homolog subfamily B member 9

1

0

High-throughput

0.279

Low

1339616

DKKL1
Dickkopf-like protein 1

1

0

High-throughput

0.279

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025