HitPredict

Interactor 1: RU17 (P08621)
U1 small nuclear ribonucleoprotein 70 kDa (U1 snRNP 70 kDa) (U1-70K) (snRNP70)
Gene: SNRNP70

Interactor 2: PABP4 (Q13310)
Polyadenylate-binding protein 4 (PABP-4) (Poly(A)-binding protein 4) (Activated-platelet protein 1) (APP-1) (Inducible poly(A)-binding protein) (iPABP)
Gene: PABPC4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29802200
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1, RRM_1~U1snRNP70_N
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 437 Hs			1 644
+	Hs
		516495 PABP1_HUMAN (4-361): 2.68e-53: 190: 11.08		PABP4_HUMAN (1-644): 0: 585: 100.00
+	Hs
		516339 PABP1_HUMAN (4-361): 2.68e-53: 190: 11.08		PABP1_HUMAN (1-644): 0: 542: 74.54
+	Hs
		441852 RU17_HUMAN (1-437): 8.99e-46: 165: 100.00		PABP1_HUMAN (1-644): 0: 542: 74.54
+	Hs
		516689 PABP1_HUMAN (4-361): 2.68e-53: 190: 11.08		PABP3_HUMAN (1-644): 7.04e-175: 513: 68.98
+	Hs
		1119141 PABP5_HUMAN (4-350): 4.45e-37: 141: 11.14		PAP1L_HUMAN (1-636): 6.79e-165: 487: 63.89
+	Sc
		376897 RU17_YEAST (3-297): 9.1e-46: 162: 26.58		PABP_YEAST (2-290): 4.28e-66: 228: 30.07
+	Hs
		1055876 PABP5_HUMAN (4-350): 4.45e-37: 141: 11.14		ELAV3_HUMAN (3-272): 2.13e-40: 153: 19.15
+	Hs
		516355 PABP1_HUMAN (4-361): 2.68e-53: 190: 11.08		NUCL_HUMAN (2-89): 1.4e-20: 98.4: 31.82
+	Hs
		474034 PABP5_HUMAN (4-350): 4.45e-37: 141: 11.14		PAB4L_HUMAN (192-380): 4.58e-38: 146: 31.05
+	Hs
		474021 PABP4_HUMAN (2-265): 2.72e-31: 128: 11.81		PAB4L_HUMAN (192-380): 4.58e-38: 146: 31.05
+	Hs
		516635 PABP1_HUMAN (4-361): 2.68e-53: 190: 11.08		PABP5_HUMAN (4-93): 1.22e-15: 81: 23.33
+	Hs
		441875 RU17_HUMAN (1-437): 8.99e-46: 165: 100.00		NUCL_HUMAN (2-89): 1.4e-20: 98.4: 31.82
+	Mm
		665745 PABP1_MOUSE (4-361): 4.42e-53: 189: 11.08		TIA1_MOUSE (4-86): 1.26e-12: 72: 30.12
+	Mm
		857334 RU17_MOUSE (1-437): 1.33e-49: 176: 89.78		TIA1_MOUSE (4-86): 1.26e-12: 72: 30.12
+	Hs
		441896 RU17_HUMAN (1-437): 8.99e-46: 165: 100.00		TIA1_HUMAN (4-109): 7.62e-12: 69.5: 24.53
+	Hs
		1288654 RBM7_HUMAN (96-357): 1.08e-35: 134: 18.73		PABP5_HUMAN (4-93): 1.22e-15: 81: 23.33