Protein: NOC3
Nucleolar complex-associated protein 3

Gene: NOC3
Organism: Saccharomyces cerevisiae S288C
Interactions: 145
UniProt ID: Q07896

Gene Ontology (top 5):
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005656 - nuclear pre-replicative complex
GO:0005730 - nucleolus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

814400

NOC2
Nucleolar complex protein 2

12

2

Small-scale

0.979

High

830193

NOP2
25S rRNA

4

4

Small-scale

0.881

High

677245

SPB1
27S pre-rRNA

4

3

High-throughput

0.873

High

917568

NSA1
Ribosome biogenesis protein NSA1

8

2

Small-scale

0.747

High

816916

NUG1
Nuclear GTP-binding protein NUG1

8

5

Small-scale

0.744

High

682403

SPB4
ATP-dependent rRNA helicase SPB4

6

12

High-throughput

0.726

High

919019

PESC
Pescadillo homolog

5

3

Small-scale

0.709

High

1060747

YTM1
Ribosome biogenesis protein YTM1

5

3

Small-scale

0.709

High

1060757

IF6
Eukaryotic translation initiation factor 6

4

1

Small-scale

0.694

High

782463

RPF2
Ribosome biogenesis protein RPF2

4

1

High-throughput

0.687

High

806664

RIX1
Pre-rRNA-processing protein RIX1

4

1

Small-scale

0.686

High

804672

SSF1
Ribosome biogenesis protein SSF1

4

3

Small-scale

0.676

High

803949

CIC1
Proteasome-interacting protein CIC1

3

3

High-throughput

0.656

High

850025

LOC1
60S ribosomal subunit assembly/export protein LOC1

3

1

High-throughput

0.650

High

534151

MAK16
Protein MAK16

3

3

High-throughput

0.646

High

780329

EBP2
rRNA-processing protein EBP2

3

2

High-throughput

0.646

High

1060745

RRS1
Regulator of ribosome biosynthesis

3

4

High-throughput

0.643

High

1039640

NOG1
Nucleolar GTP-binding protein 1

3

2

Small-scale

0.640

High

1043298

HAS1
ATP-dependent RNA helicase HAS1

3

13

High-throughput

0.640

High

1044906

RRP17
Ribosomal RNA-processing protein 17

3

1

High-throughput

0.640

High

1060737

NOC3
Nucleolar complex-associated protein 3

3

2

Small-scale

0.640

High

1060755

DBP10
ATP-dependent RNA helicase DBP10

3

6

High-throughput

0.640

High

925449

RCM1
25S rRNA

1

4

High-throughput

0.618

High

1060746

NIP7
60S ribosome subunit biogenesis protein NIP7

1

2

High-throughput

0.618

High

1047290

ERB1
Ribosome biogenesis protein ERB1

2

4

High-throughput

0.611

High

1054253

FKBP4
FK506-binding protein 4

2

4

High-throughput

0.611

High

1060740

BRX1
Ribosome biogenesis protein BRX1

2

12

High-throughput

0.611

High

1060748

NOP53
Ribosome biogenesis protein NOP53

2

1

High-throughput

0.586

High

633198

MAK11
Protein MAK11

2

3

Small-scale

0.584

High

750155

MRT4
Ribosome assembly factor MRT4

2

4

Small-scale

0.584

High

827622

RLP7
Ribosome biogenesis protein RLP7

2

5

High-throughput

0.584

High

924856

NOP15
Ribosome biogenesis protein 15

2

4

High-throughput

0.584

High

1060742

PUS7
Multisubstrate pseudouridine synthase 7

2

0

High-throughput

0.576

High

805101

RPF1
Ribosome production factor 1

2

3

High-throughput

0.571

High

525335

HSP71
Heat shock protein SSA1

2

4

High-throughput

0.552

High

671181

SIS1
Protein SIS1

2

0

High-throughput

0.547

High

722308

XPO1
Exportin-1

1

2

High-throughput

0.536

High

1060752

YRA1
RNA annealing protein YRA1

1

1

High-throughput

0.515

High

586035

CSK21
Casein kinase II subunit alpha

1

0

High-throughput

0.513

High

743299

PP12
Serine/threonine-protein phosphatase PP1-2

1

0

High-throughput

0.513

High

1030589

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

0

High-throughput

0.513

High

809427

STM1
Suppressor protein STM1

1

0

High-throughput

0.493

High

1060743

HRK1
Serine/threonine-protein kinase HRK1

1

1

High-throughput

0.489

High

1060749

RTK1
Probable serine/threonine-protein kinase RTK1

1

1

High-throughput

0.489

High

917069

MCM6
DNA replication licensing factor MCM6

1

1

Small-scale

0.481

High

1060753

SMT3
Ubiquitin-like protein SMT3

1

1

High-throughput

0.481

High

149980

RS9A
Small ribosomal subunit protein uS4A

1

2

High-throughput

0.479

High

381654

H2B2
Histone H2B.2

1

1

High-throughput

0.479

High

403675

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

1

High-throughput

0.479

High

419891

H2A2
Histone H2A.2

1

3

High-throughput

0.479

High

433874

RL26A
Large ribosomal subunit protein uL24A

1

2

High-throughput

0.479

High

435397

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.479

High

436199

RS13
Small ribosomal subunit protein uS15

1

1

High-throughput

0.479

High

442136

RS14A
Small ribosomal subunit protein uS11A

1

2

High-throughput

0.479

High

444637

DED1
ATP-dependent RNA helicase DED1

1

1

High-throughput

0.479

High

512681

RS6A
Small ribosomal subunit protein eS6A

1

3

High-throughput

0.479

High

672962

RRP43
Exosome complex component RRP43

1

1

High-throughput

0.479

High

674864

RS2
Small ribosomal subunit protein uS5

1

1

High-throughput

0.479

High

680112

CDC48
Cell division control protein 48

1

1

High-throughput

0.479

High

689150

RL16A
Large ribosomal subunit protein uL13A

1

2

High-throughput

0.479

High

689692

RS7A
Small ribosomal subunit protein eS7A

1

1

High-throughput

0.479

High

708352

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

713043

MCM2
DNA replication licensing factor MCM2

1

1

Small-scale

0.479

High

713309

MCM5
Minichromosome maintenance protein 5

1

2

Small-scale

0.479

High

746681

DRS1
ATP-dependent RNA helicase DRS1

1

11

High-throughput

0.479

High

751499

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

1

1

High-throughput

0.479

High

763127

RRP1
Ribosomal RNA-processing protein 1

1

4

High-throughput

0.479

High

780714

RRP14
Ribosomal RNA-processing protein 14

1

1

High-throughput

0.479

High

792276

GBLP
Small ribosomal subunit protein RACK1

1

4

High-throughput

0.479

High

798329

ENP1
Essential nuclear protein 1

1

2

High-throughput

0.479

High

807158

FKBP3
Peptidyl-prolyl cis-trans isomerase

1

4

High-throughput

0.479

High

816803

NOP16
Nucleolar protein 16

1

1

High-throughput

0.479

High

818282

NSA2
Ribosome biogenesis protein NSA2

1

1

High-throughput

0.479

High

844636

UTP10
U3 small nucleolar RNA-associated protein 10

1

1

High-throughput

0.479

High

923211

NOG2
Nucleolar GTP-binding protein 2

1

5

High-throughput

0.479

High

924253

IPI3
Pre-rRNA-processing protein IPI3

1

3

Small-scale

0.479

High

924339

NOP13
Nucleolar protein 13

1

1

High-throughput

0.479

High

925097

APJ1
J domain-containing protein APJ1

1

3

High-throughput

0.479

High

1038762

XRN2
5'-3' exoribonuclease 2

1

2

High-throughput

0.479

High

1044226

ARX1
Probable metalloprotease ARX1

1

1

High-throughput

0.479

High

1046058

DHR1
Probable ATP-dependent RNA helicase DHR1

1

1

High-throughput

0.479

High

1046122

RRB1
Ribosome assembly protein RRB1

1

2

High-throughput

0.479

High

1046526

PUF6
Pumilio homology domain family member 6

1

1

High-throughput

0.479

High

1054367

JIP5
WD repeat-containing protein JIP5

1

5

High-throughput

0.479

High

1055473

RRP15
Ribosomal RNA-processing protein 15

1

1

High-throughput

0.479

High

1055496

NOC4
Nucleolar complex protein 4

1

3

High-throughput

0.479

High

1060738

RLP24
Ribosome biogenesis protein RLP24

1

3

High-throughput

0.479

High

1060739

NOP12
Nucleolar protein 12

1

6

High-throughput

0.479

High

1060741

SGO1
Shugoshin

1

1

High-throughput

0.479

High

1060750

RRP6
Exosome complex exonuclease RRP6

1

2

High-throughput

0.479

High

1060751

SCC1
Sister chromatid cohesion protein 1

1

1

High-throughput

0.479

High

1060756

NOP58
Nucleolar protein 58

1

6

High-throughput

0.479

High

745670

ORC2
Origin recognition complex subunit 2

1

0

Small-scale

0.460

High

805528

ORC6
Origin recognition complex subunit 6

1

0

Small-scale

0.460

High

865465

CDT1
Cell division cycle protein CDT1

1

0

Small-scale

0.460

High

898176

ORC5
Origin recognition complex subunit 5

1

0

Small-scale

0.460

High

932318

ORC3
Origin recognition complex subunit 3

1

0

Small-scale

0.460

High

645001

RPA2
DNA-directed RNA polymerase I subunit RPA135

1

0

High-throughput

0.458

High

677973

YCQ6
Uncharacterized protein YCR016W

1

0

High-throughput

0.458

High

735192

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

795849

YBC8
UPF0642 protein YBL028C

1

0

High-throughput

0.458

High

826885

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.458

High

923066

TR112
Multifunctional methyltransferase subunit TRM112

1

0

Small-scale

0.458

High

932238

ORC1
Origin recognition complex subunit 1

1

0

Small-scale

0.458

High

1044312

MTQ2
eRF1 methyltransferase catalytic subunit MTQ2

1

0

High-throughput

0.458

High

1044791

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

1054854

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.458

High

527833

HSP72
Heat shock protein SSA2

1

4

High-throughput

0.445

High

546503

SSB1
Ribosome-associated molecular chaperone SSB1

1

4

High-throughput

0.445

High

742528

HSP7F
Heat shock protein homolog SSE1

1

6

High-throughput

0.445

High

819953

SSB2
Ribosome-associated molecular chaperone SSB2

1

4

High-throughput

0.445

High

758158

CASP
Protein CASP

1

2

High-throughput

0.439

High

410364

RL25
Large ribosomal subunit protein uL23

1

3

High-throughput

0.437

High

430934

ERF3
Eukaryotic peptide chain release factor GTP-binding subunit

1

1

Small-scale

0.437

High

455290

RS19A
Small ribosomal subunit protein eS19A

1

3

High-throughput

0.437

High

504442

RL31A
Large ribosomal subunit protein eL31A

1

3

High-throughput

0.437

High

513250

RS8A
Small ribosomal subunit protein eS8A

1

2

High-throughput

0.437

High

514861

RS18A
Small ribosomal subunit protein uS13A

1

1

High-throughput

0.437

High

753616

RS3A1
Small ribosomal subunit protein eS1A

1

2

High-throughput

0.437

High

778562

RS27A
Small ribosomal subunit protein eS27A

1

1

High-throughput

0.437

High

785984

LONM
Lon protease homolog, mitochondrial

1

1

High-throughput

0.437

High

802416

RS20
Small ribosomal subunit protein uS10

1

1

High-throughput

0.437

High

874558

RS12
Small ribosomal subunit protein eS12

1

1

High-throughput

0.437

High

1033596

RS15
Small ribosomal subunit protein uS19

1

1

High-throughput

0.437

High

1046316

VMS1
tRNA endonuclease VMS1

1

3

High-throughput

0.437

High

1060744

RS10A
Small ribosomal subunit protein eS10A

1

2

High-throughput

0.437

High

912461

PFD6
Prefoldin subunit 6

1

0

High-throughput

0.426

High

1025191

SEN1
Helicase SEN1

1

0

Small-scale

0.426

High

671724

SCJ1
DnaJ-related protein SCJ1

1

1

High-throughput

0.407

High

752806

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.407

High

816438

HSP7E
Heat shock protein SSC3, mitochondrial

1

1

High-throughput

0.407

High

823298

JEM1
DnaJ-like chaperone JEM1

1

3

High-throughput

0.407

High

580162

HSC82
ATP-dependent molecular chaperone HSC82

2

0

High-throughput

0.298

High

866037

YMR1
Phosphoinositide 3-phosphatase

1

0

High-throughput

0.279

Low

744563

FADH
S-(hydroxymethyl)glutathione dehydrogenase

1

0

High-throughput

0.269

Low

1026973

TPS1
Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 56 kDa subunit

1

0

High-throughput

0.269

Low

432036

ATPF
ATP synthase subunit 4, mitochondrial

1

0

High-throughput

0.251

Low

558879

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.249

Low

748564

SC61A
Protein transport protein SEC61

1

0

High-throughput

0.249

Low

812710

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

1025054

NUM1
Nuclear migration protein NUM1

1

0

High-throughput

0.249

Low

1059368

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.249

Low

705229

PEX3
Peroxisomal biogenesis factor 3

1

0

High-throughput

0.238

Low

1060754

JID1
J domain-containing protein 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025