HitPredict

Interactor 1: RU17 (P08621)
U1 small nuclear ribonucleoprotein 70 kDa (U1 snRNP 70 kDa) (U1-70K) (snRNP70)
Gene: SNRNP70

Interactor 2: RBP56 (Q92804)
TATA-binding protein-associated factor 2N (68 kDa TATA-binding protein-associated factor) (TAF(II)68) (TAFII68) (RNA-binding protein 56)
Gene: TAF15

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	29802200, 29884807
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1, RRM_1~U1snRNP70_N
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 437 Hs			1 592
+	Hs
		516620 PABP1_HUMAN (4-361): 2.68e-53: 190: 11.08		RBP56_HUMAN (1-394): 3.45e-37: 148: 100.00
+	Hs
		516383 PABP1_HUMAN (4-361): 2.68e-53: 190: 11.08		FUS_HUMAN (8-381): 2.72e-32: 132: 39.28
+	Hs
		442081 RU17_HUMAN (1-437): 8.99e-46: 165: 100.00		EWS_HUMAN (4-383): 3.73e-35: 142: 32.96
+	Hs
		441912 RU17_HUMAN (1-437): 8.99e-46: 165: 100.00		FUS_HUMAN (8-381): 2.72e-32: 132: 39.28
+	Hs
		212095 RU17_HUMAN (1-437): 8.99e-46: 165: 100.00		HTSF1_HUMAN (113-325): 5.58e-31: 130: 18.06
+	Hs
		1031411 PABP4_HUMAN (2-265): 2.72e-31: 128: 11.81		RBP56_HUMAN (1-394): 3.45e-37: 148: 100.00
+	Hs
		726950 PPIL4_HUMAN (63-356): 2.16e-35: 138: 17.17		FUS_HUMAN (8-381): 2.72e-32: 132: 39.28
+	Hs
		727116 RBM7_HUMAN (96-357): 1.08e-35: 134: 18.73		FUS_HUMAN (8-381): 2.72e-32: 132: 39.28
+	Hs
		212193 RBM7_HUMAN (96-357): 1.08e-35: 134: 18.73		HTSF1_HUMAN (113-325): 5.58e-31: 130: 18.06
+	Hs
		726795 PABP4_HUMAN (2-265): 2.72e-31: 128: 11.81		FUS_HUMAN (8-381): 2.72e-32: 132: 39.28
+	Mm
		857328 TIA1_MOUSE (3-246): 4.89e-27: 113: 13.42		EWS_MOUSE (4-383): 9.82e-32: 132: 33.26
+	Hs
		703370 CSTF2_HUMAN (85-177): 1.23e-20: 96.4: 32.26		EWS_HUMAN (4-383): 3.73e-35: 142: 32.96
+	Hs
		967422 CSTFT_HUMAN (84-177): 2.89e-20: 95.3: 30.85		EWS_HUMAN (4-383): 3.73e-35: 142: 32.96
+	Mm
		1207134 CSTFT_MOUSE (84-177): 9.89e-20: 93.7: 30.85		Q8BQ46_MOUSE (1-394): 3.73e-35: 141: 94.16
+	Hs
		963541 TIAR_HUMAN (97-338): 4.83e-20: 93.1: 14.18		LFG1_HUMAN (26-147): 8.74e-36: 140: 25.81
+	Hs
		680441 TIA1_HUMAN (98-338): 2.21e-18: 88.4: 12.95		EWS_HUMAN (4-383): 3.73e-35: 142: 32.96
+	Hs
		703359 CSTF2_HUMAN (85-177): 1.23e-20: 96.4: 32.26		FUS_HUMAN (8-381): 2.72e-32: 132: 39.28
+	Hs
		235808 HNRPQ_HUMAN (4-313): 1.11e-16: 84.2: 13.55		EWS_HUMAN (4-383): 3.73e-35: 142: 32.96
+	Mm
		1142771 CSTFT_MOUSE (84-177): 9.89e-20: 93.7: 30.85		EWS_MOUSE (4-383): 9.82e-32: 132: 33.26
+	Hs
		235735 HNRPQ_HUMAN (4-313): 1.11e-16: 84.2: 13.55		FUS_HUMAN (8-381): 2.72e-32: 132: 39.28