Protein: HGF
Hepatocyte growth factor (Hepatopoietin-A) (Scatter factor) (SF) [Cleaved into: Hepatocyte growth factor alpha chain; Hepatocyte growth factor beta chain]

Gene: HGF
Organism: Homo sapiens
Interactions: 47
UniProt ID: P14210

Gene Ontology (top 5):
GO:0000278 - mitotic cell cycle
GO:0000902 - cell morphogenesis
GO:0001837 - epithelial to mesenchymal transition
GO:0001889 - liver development
GO:0001934 - positive regulation of protein phosphorylation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

441419

MET
Hepatocyte growth factor receptor

12

20

Small-scale

0.978

High

536113

HGF
Hepatocyte growth factor

4

17

Small-scale

0.888

High

536133

HGFA
Hepatocyte growth factor activator

1

17

Small-scale

0.692

High

270259

LRP6
Low-density lipoprotein receptor-related protein 6

1

8

High-throughput

0.691

High

536127

NOTC1
Neurogenic locus notch homolog protein 1

1

12

High-throughput

0.691

High

536140

SORL
Sortilin-related receptor

1

11

High-throughput

0.691

High

238753

SRPX2
Sushi repeat-containing protein SRPX2

1

6

Small-scale

0.647

High

380903

VWF
von Willebrand factor

1

11

Small-scale

0.647

High

536131

PGBM
Basement membrane-specific heparan sulfate proteoglycan core protein

1

6

Small-scale

0.647

High

536144

FKBP7
Peptidyl-prolyl cis-trans isomerase FKBP7

3

4

High-throughput

0.599

High

345823

MYC
Myc proto-oncogene protein

2

7

High-throughput

0.595

High

536128

MEOX2
Homeobox protein MOX-2

1

3

High-throughput

0.573

High

536137

ATL4
ADAMTS-like protein 4

1

6

High-throughput

0.573

High

362770

FINC
Fibronectin

1

11

Small-scale

0.501

High

373621

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

2

High-throughput

0.501

High

383573

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

17

High-throughput

0.501

High

402814

TETN
Tetranectin

1

3

Small-scale

0.501

High

536115

PGFRA
Platelet-derived growth factor receptor alpha

1

5

High-throughput

0.501

High

536117

FGFR4
Fibroblast growth factor receptor 4

1

12

High-throughput

0.501

High

536118

TENA
Tenascin

1

14

Small-scale

0.501

High

536119

ARNT
Aryl hydrocarbon receptor nuclear translocator

1

3

High-throughput

0.501

High

536120

EPHA2
Ephrin type-A receptor 2

1

18

High-throughput

0.501

High

536126

CDN2B
Cyclin-dependent kinase 4 inhibitor B

1

6

High-throughput

0.501

High

536129

MP2K6
Dual specificity mitogen-activated protein kinase kinase 6

1

4

High-throughput

0.501

High

536130

1433G
14-3-3 protein gamma

1

3

High-throughput

0.501

High

536134

MP2K5
Dual specificity mitogen-activated protein kinase kinase 5

1

3

High-throughput

0.501

High

536136

STK11
Serine/threonine-protein kinase STK11

1

2

High-throughput

0.501

High

536141

GLIS2
Zinc finger protein GLIS2

1

1

High-throughput

0.501

High

195679

ZZEF1
Zinc finger ZZ-type and EF-hand domain-containing protein 1

1

2

High-throughput

0.489

High

536138

KBTB6
Kelch repeat and BTB domain-containing protein 6

1

2

High-throughput

0.489

High

536139

KBTB7
Kelch repeat and BTB domain-containing protein 7

1

2

High-throughput

0.489

High

536124

BRCA1
Breast cancer type 1 susceptibility protein

1

4

High-throughput

0.481

High

169237

MDM4
Protein Mdm4

1

0

High-throughput

0.480

High

372986

VTNC
Vitronectin

1

0

Small-scale

0.480

High

536121

CCND2
G1/S-specific cyclin-D2

1

0

High-throughput

0.480

High

536123

MERL
Merlin

1

0

High-throughput

0.480

High

536135

TEAD2
Transcriptional enhancer factor TEF-4

1

0

High-throughput

0.480

High

226412

PRKN
E3 ubiquitin-protein ligase parkin

1

3

High-throughput

0.479

High

515318

CDK4
Cyclin-dependent kinase 4

1

1

High-throughput

0.457

High

536114

DESP
Desmoplakin

1

3

Small-scale

0.457

High

536116

SDC1
Syndecan-1

1

1

Small-scale

0.457

High

536122

SDC2
Syndecan-2

1

1

Small-scale

0.457

High

536125

CDN2A
Cyclin-dependent kinase inhibitor 2A

1

6

High-throughput

0.457

High

536132

CDK6
Cyclin-dependent kinase 6

1

1

High-throughput

0.457

High

536143

LATS2
Serine/threonine-protein kinase LATS2

1

5

High-throughput

0.457

High

536142

TRI31
E3 ubiquitin-protein ligase TRIM31

1

3

High-throughput

0.437

High


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Last updated: 15 Jul 2024