HitPredict

Interactor 1: RAP1 (P08645)
Ras-related protein Rap1 (EC 3.6.5.2) (Rap1 GTPase) (Ras-like protein 3)
Gene: RAP1

Interactor 2: Q95TT5 (Q95TT5)
LD24616p
Gene: cno

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	1.00	0.590

Property	Details
Experiments	15710747
Identification Methods	two hybrid fragment pooling approach
Interaction Type	physical association

Property	Details
Interacting Pfam domains	DIL~Ras, PDZ~Ras, RA~Ras
Common GO terms	GO:0007391 - dorsal closure
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 184 Dm			1 2051
+	Dm
		442960 RAP1_DROME (1-184): 7.38e-88: 257: 100.00		Q8IPP3_DROME (1-1757): 0: 1079: 66.42
+	Hs
		876348 RAP1A_HUMAN (1-184): 1.49e-87: 256: 85.95		AFAD_HUMAN (1-1926): 0: 909: 31.37
+	Dm
		442954 RAP1_DROME (1-184): 7.38e-88: 257: 100.00		Q24279_DROME (1-526): 3.71e-169: 569: 94.68
+	Rn
		914521 RB11A_RAT (4-179): 6.45e-75: 225: 28.81		MYO5B_RAT (83-955): 7.49e-177: 590: 14.83
+	Hs
		914453 RB11A_HUMAN (4-179): 6.45e-75: 225: 28.81		MYO5B_HUMAN (82-955): 4.28e-173: 579: 14.94
+	Hs
		1079976 RB11B_HUMAN (4-176): 1.4e-73: 222: 29.89		MYO5B_HUMAN (82-955): 4.28e-173: 579: 14.94
+	Hs
		914486 RB11A_HUMAN (4-179): 6.45e-75: 225: 28.81		MYO5A_HUMAN (83-950): 3.57e-163: 551: 13.60
+	Hs
		914383 RB11A_HUMAN (4-179): 6.45e-75: 225: 28.81		MYO5C_HUMAN (97-963): 1.98e-154: 524: 12.95
+	Dm
		51909 O18335_DROME (4-176): 6.54e-75: 225: 31.03		A1Z6Z9_DROME (83-934): 5.26e-139: 480: 12.43
+	Hs
		919631 RAP1A_HUMAN (1-184): 1.49e-87: 256: 85.95		KIF14_HUMAN (189-684): 1.34e-61: 236: 16.51
+	Hs
		918872 RAB1A_HUMAN (4-170): 5.46e-76: 228: 34.52		KIF14_HUMAN (189-684): 1.34e-61: 236: 16.51
+	Hs
		1066669 RAB1B_HUMAN (4-170): 1.78e-75: 226: 32.74		KIF14_HUMAN (189-684): 1.34e-61: 236: 16.51
+	Hs
		914382 RB11A_HUMAN (4-179): 6.45e-75: 225: 28.81		KI13B_HUMAN (249-711): 8.15e-62: 237: 14.62
+	Hs
		914346 RB11A_HUMAN (4-179): 6.45e-75: 225: 28.81		KI13A_HUMAN (249-711): 5.05e-61: 234: 15.70
+	Hs
		895083 RAB2A_HUMAN (4-170): 1.54e-72: 219: 38.10		KIF14_HUMAN (189-684): 1.34e-61: 236: 16.51
+	Hs
		914285 RB11A_HUMAN (4-179): 6.45e-75: 225: 28.81		KI16B_HUMAN (186-991): 6.41e-50: 197: 12.79
+	Mm
		918987 RAB1A_MOUSE (4-170): 5.46e-76: 228: 34.52		NEB2_MOUSE (995-1167): 1.5e-37: 155: 28.18
+	Mm
		895596 RAB8B_MOUSE (4-180): 8.19e-73: 219: 33.15		NEB2_MOUSE (995-1167): 1.5e-37: 155: 28.18
+	Hs
		919668 RAP1A_HUMAN (1-184): 1.49e-87: 256: 85.95		RADIL_HUMAN (882-1110): 1.85e-20: 101: 19.91
+	Hs
		914066 RB11A_HUMAN (4-179): 6.45e-75: 225: 28.81		SCRIB_HUMAN (992-1538): 4.1e-27: 123: 12.52