Protein: RPB7
DNA-directed RNA polymerase II subunit RPB7 (RNA polymerase II subunit B7) (DNA-directed RNA polymerase II subunit G) (RNA polymerase II 19 kDa subunit) (RPB19)

Gene: RPB7, POLR2G
Organism: Homo sapiens
Interactions: 172
UniProt ID: P62487

Gene Ontology (top 5):
GO:0000932 - P-body
GO:0000956 - nuclear-transcribed mRNA catabolic process
GO:0003697 - single-stranded DNA binding
GO:0003727 - single-stranded RNA binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

667253

RPB1
DNA-directed RNA polymerase II subunit RPB1

11

12

Small-scale

0.977

High

192806

RPB4
DNA-directed RNA polymerase II subunit RPB4

9

4

Small-scale

0.974

High

722931

RPB2
DNA-directed RNA polymerase II subunit RPB2

8

11

High-throughput

0.966

High

958927

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

6

5

Small-scale

0.948

High

262506

MCE1
mRNA-capping enzyme

3

1

High-throughput

0.847

High

130427

SPT5H
Transcription elongation factor SPT5

2

1

High-throughput

0.811

High

976085

TF2B
Transcription initiation factor IIB

2

4

High-throughput

0.811

High

912169

RPB11
DNA-directed RNA polymerase II subunit RPB11-a

9

5

Small-scale

0.752

High

316274

RECQ5
ATP-dependent DNA helicase Q5

7

2

Small-scale

0.747

High

787741

RPB9
DNA-directed RNA polymerase II subunit RPB9

7

9

High-throughput

0.747

High

976112

RPAP2
Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2

7

2

High-throughput

0.747

High

912046

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

7

5

Small-scale

0.746

High

703528

MK01
Mitogen-activated protein kinase 1

2

0

High-throughput

0.742

High

976099

DUS29
Dual specificity phosphatase 29

2

0

High-throughput

0.742

High

976125

GPKOW
G-patch domain and KOW motifs-containing protein

2

0

High-throughput

0.742

High

621852

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

6

4

Small-scale

0.739

High

621619

RPB3
DNA-directed RNA polymerase II subunit RPB3

6

8

Small-scale

0.737

High

976156

GPN1
GPN-loop GTPase 1

6

4

High-throughput

0.732

High

976183

CTDP1
RNA polymerase II subunit A C-terminal domain phosphatase

5

1

High-throughput

0.722

High

335978

MED26
Mediator of RNA polymerase II transcription subunit 26

8

0

High-throughput

0.720

High

976096

RPRD2
Regulation of nuclear pre-mRNA domain-containing protein 2

5

5

High-throughput

0.718

High

976158

RPR1B
Regulation of nuclear pre-mRNA domain-containing protein 1B

5

8

High-throughput

0.716

High

976083

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

5

4

Small-scale

0.716

High

976164

PIHD1
PIH1 domain-containing protein 1

5

1

High-throughput

0.714

High

976151

SFR19
Splicing factor, arginine/serine-rich 19

5

1

High-throughput

0.712

High

976135

RPR1A
Regulation of nuclear pre-mRNA domain-containing protein 1A

4

7

High-throughput

0.699

High

976160

MED17
Mediator of RNA polymerase II transcription subunit 17

5

0

High-throughput

0.682

High

976131

MED30
Mediator of RNA polymerase II transcription subunit 30

4

0

High-throughput

0.670

High

681782

RBTN2
Rhombotin-2

4

0

High-throughput

0.669

High

239560

MED14
Mediator of RNA polymerase II transcription subunit 14

3

5

High-throughput

0.667

High

923486

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

3

4

Small-scale

0.660

High

976175

GPN3
GPN-loop GTPase 3

5

4

High-throughput

0.654

High

180267

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

3

8

High-throughput

0.653

High

976082

RPB7
DNA-directed RNA polymerase II subunit RPB7

1

2

Small-scale

0.647

High

976101

GL1AD
DNA-directed RNA polymerase II subunit GRINL1A, isoforms 4/5

5

1

High-throughput

0.641

High

48936

MED19
Mediator of RNA polymerase II transcription subunit 19

3

0

High-throughput

0.638

High

976163

MED9
Mediator of RNA polymerase II transcription subunit 9

3

0

High-throughput

0.638

High

770368

T2FA
General transcription factor IIF subunit 1

2

1

High-throughput

0.628

High

506006

GRL1A
DNA-directed RNA polymerase II subunit GRINL1A

4

0

High-throughput

0.623

High

976093

MED1
Mediator of RNA polymerase II transcription subunit 1

3

0

High-throughput

0.622

High

165032

RPC1
DNA-directed RNA polymerase III subunit RPC1

1

12

High-throughput

0.618

High

287450

RPC9
DNA-directed RNA polymerase III subunit RPC9

1

5

High-throughput

0.618

High

339965

RPA1
DNA-directed RNA polymerase I subunit RPA1

1

12

High-throughput

0.618

High

976144

CDK19
Cyclin-dependent kinase 19

1

2

High-throughput

0.618

High

976153

RPA2
DNA-directed RNA polymerase I subunit RPA2

1

11

High-throughput

0.618

High

976162

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

11

High-throughput

0.618

High

976182

RPC8
DNA-directed RNA polymerase III subunit RPC8

1

2

High-throughput

0.618

High

131906

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

2

3

High-throughput

0.611

High

569084

T2FB
General transcription factor IIF subunit 2

2

1

High-throughput

0.611

High

976157

MED4
Mediator of RNA polymerase II transcription subunit 4

2

1

High-throughput

0.611

High

976127

UPP
Uracil phosphoribosyltransferase homolog

2

1

High-throughput

0.606

High

822578

VHL
von Hippel-Lindau disease tumor suppressor

2

0

Small-scale

0.605

High

976142

MED18
Mediator of RNA polymerase II transcription subunit 18

2

0

High-throughput

0.602

High

976166

MED29
Mediator of RNA polymerase II transcription subunit 29

2

0

High-throughput

0.602

High

976181

MED31
Mediator of RNA polymerase II transcription subunit 31

2

0

High-throughput

0.602

High

976086

HXC5
Homeobox protein Hox-C5

2

0

High-throughput

0.589

High

287777

MED6
Mediator of RNA polymerase II transcription subunit 6

2

0

High-throughput

0.585

High

976089

MED21
Mediator of RNA polymerase II transcription subunit 21

2

0

High-throughput

0.585

High

976141

MED10
Mediator of RNA polymerase II transcription subunit 10

2

0

High-throughput

0.585

High

584079

FOSL2
Fos-related antigen 2

2

0

High-throughput

0.580

High

606097

DESM
Desmin

2

0

High-throughput

0.580

High

700449

PSB8
Proteasome subunit beta type-8

2

0

High-throughput

0.580

High

807351

IF4A3
Eukaryotic initiation factor 4A-III

2

0

High-throughput

0.580

High

976095

B2L15
Bcl-2-like protein 15

2

0

High-throughput

0.580

High

976100

TRI68
E3 ubiquitin-protein ligase TRIM68

2

0

High-throughput

0.580

High

976111

ZN410
Zinc finger protein 410

2

0

High-throughput

0.580

High

976120

SEN15
tRNA-splicing endonuclease subunit Sen15

2

0

High-throughput

0.580

High

976178

TPC2L
Trafficking protein particle complex subunit 2-like protein

2

0

High-throughput

0.580

High

91546

C9J2Y9
DNA-directed RNA polymerase subunit beta

1

11

High-throughput

0.575

High

976148

MED28
Mediator of RNA polymerase II transcription subunit 28

2

0

High-throughput

0.559

High

749893

KINH
Kinesin-1 heavy chain

2

1

High-throughput

0.553

High

976118

DDX54
ATP-dependent RNA helicase DDX54

1

1

High-throughput

0.541

High

976124

RBP56
TATA-binding protein-associated factor 2N

1

0

Small-scale

0.537

High

219481

MED7
Mediator of RNA polymerase II transcription subunit 7

1

1

High-throughput

0.536

High

477983

SNRPA
U1 small nuclear ribonucleoprotein A

1

1

High-throughput

0.536

High

654631

TCEA1
Transcription elongation factor A protein 1

1

5

High-throughput

0.536

High

973875

RUXF
Small nuclear ribonucleoprotein F

1

1

High-throughput

0.536

High

976088

SSRP1
FACT complex subunit SSRP1

1

1

High-throughput

0.536

High

976102

CDC73
Parafibromin

1

1

High-throughput

0.536

High

976106

UBP45
Ubiquitin carboxyl-terminal hydrolase 45

1

1

High-throughput

0.536

High

976109

SETX
Probable helicase senataxin

1

3

High-throughput

0.536

High

976117

WDR48
WD repeat-containing protein 48

1

1

High-throughput

0.536

High

976147

WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1

1

3

High-throughput

0.536

High

976150

RPAP3
RNA polymerase II-associated protein 3

2

1

High-throughput

0.521

High

976159

PDRG1
p53 and DNA damage-regulated protein 1

2

1

High-throughput

0.521

High

245686

GANP
Germinal-center associated nuclear protein

1

0

High-throughput

0.518

High

286928

PRKRA
Interferon-inducible double-stranded RNA-dependent protein kinase activator A

1

0

High-throughput

0.518

High

581639

MYOD1
Myoblast determination protein 1

1

0

High-throughput

0.518

High

480084

RU1C
U1 small nuclear ribonucleoprotein C

1

0

High-throughput

0.513

High

541928

TOP1
DNA topoisomerase 1

1

0

High-throughput

0.513

High

881030

NASP
Nuclear autoantigenic sperm protein

1

0

High-throughput

0.513

High

976105

CTR9
RNA polymerase-associated protein CTR9 homolog

1

0

High-throughput

0.513

High

976108

MCM10
Protein MCM10 homolog

1

0

High-throughput

0.513

High

976115

PAF1
RNA polymerase II-associated factor 1 homolog

1

0

High-throughput

0.513

High

976119

LEO1
RNA polymerase-associated protein LEO1

1

0

High-throughput

0.513

High

976137

MED15
Mediator of RNA polymerase II transcription subunit 15

1

0

High-throughput

0.513

High

976140

EPAS1
Endothelial PAS domain-containing protein 1

1

0

High-throughput

0.513

High

976146

UBP44
Ubiquitin carboxyl-terminal hydrolase 44

1

0

High-throughput

0.513

High

976179

MED16
Mediator of RNA polymerase II transcription subunit 16

1

0

High-throughput

0.513

High

230519

KIF1C
Kinesin-like protein KIF1C

1

1

High-throughput

0.489

High

891933

WHR1
Winged helix repair factor 1

1

0

Small-scale

0.486

High

976091

TRI14
Tripartite motif-containing protein 14

1

1

High-throughput

0.481

High

172663

XPO1
Exportin-1

1

3

High-throughput

0.479

High

190868

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

1

High-throughput

0.479

High

315397

RECQ4
ATP-dependent DNA helicase Q4

1

2

High-throughput

0.479

High

316378

RMP
Unconventional prefoldin RPB5 interactor 1

1

1

High-throughput

0.479

High

326317

SCAF4
SR-related and CTD-associated factor 4

1

1

High-throughput

0.479

High

430621

RPC4
DNA-directed RNA polymerase III subunit RPC4

1

2

High-throughput

0.479

High

798948

BRCA1
Breast cancer type 1 susceptibility protein

1

3

High-throughput

0.479

High

948504

ELOF1
Transcription elongation factor 1 homolog

1

1

Small-scale

0.479

High

976087

ERCC6
DNA excision repair protein ERCC-6

1

1

Small-scale

0.479

High

976107

MD13L
Mediator of RNA polymerase II transcription subunit 13-like

1

1

High-throughput

0.479

High

976123

ESR2
Estrogen receptor beta

1

2

High-throughput

0.479

High

976139

RING2
E3 ubiquitin-protein ligase RING2

1

3

High-throughput

0.479

High

976145

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

1

High-throughput

0.479

High

976161

RPC5
DNA-directed RNA polymerase III subunit RPC5

1

2

High-throughput

0.479

High

976169

RPA12
DNA-directed RNA polymerase I subunit RPA12

1

10

High-throughput

0.479

High

976171

UXT
Protein UXT

1

1

High-throughput

0.479

High

976173

MED13
Mediator of RNA polymerase II transcription subunit 13

1

1

High-throughput

0.479

High

976174

PFD2
Prefoldin subunit 2

1

1

High-throughput

0.479

High

976180

RPC10
DNA-directed RNA polymerase III subunit RPC10

1

9

High-throughput

0.479

High

976116

MCPH1
Microcephalin

1

0

Small-scale

0.460

High

976143

RPAP1
RNA polymerase II-associated protein 1

1

0

Small-scale

0.460

High

210253

PHF1
PHD finger protein 1

1

0

Small-scale

0.458

High

241309

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

259740

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.458

High

567347

TCTP
Translationally-controlled tumor protein

1

0

High-throughput

0.458

High

606564

CEBPB
CCAAT/enhancer-binding protein beta

1

0

High-throughput

0.458

High

615516

NELFE
Negative elongation factor E

1

0

High-throughput

0.458

High

869005

TISD
mRNA decay activator protein ZFP36L2

1

0

High-throughput

0.458

High

904550

MECP2
Methyl-CpG-binding protein 2

1

0

High-throughput

0.458

High

976092

MED22
Mediator of RNA polymerase II transcription subunit 22

1

0

High-throughput

0.458

High

976098

INT3
Integrator complex subunit 3

1

0

High-throughput

0.458

High

976103

MED27
Mediator of RNA polymerase II transcription subunit 27

1

0

High-throughput

0.458

High

976104

INT5
Integrator complex subunit 5

1

0

High-throughput

0.458

High

976114

SIR6
NAD-dependent protein deacylase sirtuin-6

1

0

High-throughput

0.458

High

976126

MED12
Mediator of RNA polymerase II transcription subunit 12

1

0

High-throughput

0.458

High

976129

DCPS
m7GpppX diphosphatase

1

0

High-throughput

0.458

High

976130

MED8
Mediator of RNA polymerase II transcription subunit 8

1

0

High-throughput

0.458

High

976133

CI072
Guanine nucleotide exchange factor C9orf72

1

0

High-throughput

0.458

High

976152

MED20
Mediator of RNA polymerase II transcription subunit 20

1

0

High-throughput

0.458

High

976167

WWOX
WW domain-containing oxidoreductase

1

0

High-throughput

0.458

High

976168

MED11
Mediator of RNA polymerase II transcription subunit 11

1

0

High-throughput

0.458

High

976177

INT6
Integrator complex subunit 6

1

0

High-throughput

0.458

High

91734

C9JLU1
DNA-directed RNA polymerases I, II, and III subunit RPABC3

1

5

High-throughput

0.445

High

976134

DAA10
Dynein axonemal assembly factor 10

1

1

High-throughput

0.437

High

976170

PHRF1
PHD and RING finger domain-containing protein 1

1

1

High-throughput

0.437

High

505951

MYZAP
Myocardial zonula adherens protein

1

0

High-throughput

0.426

High

976113

SLX4
Structure-specific endonuclease subunit SLX4

1

0

High-throughput

0.426

High

976128

ARMC5
Armadillo repeat-containing protein 5

1

0

High-throughput

0.426

High

976138

NUDC1
NudC domain-containing protein 1

1

0

High-throughput

0.426

High

976154

LN28A
Protein lin-28 homolog A

1

0

High-throughput

0.426

High

187688

EIF3D
Eukaryotic translation initiation factor 3 subunit D

2

0

High-throughput

0.316

High

976121

CV015
Uncharacterized protein C22orf15

2

0

High-throughput

0.316

High

976136

CIB3
Calcium and integrin-binding family member 3

2

0

High-throughput

0.316

High

976155

PARVG
Gamma-parvin

2

0

High-throughput

0.316

High

976172

CNTP2
Contactin-associated protein-like 2

2

0

High-throughput

0.316

High

976176

OSGI1
Oxidative stress-induced growth inhibitor 1

2

0

High-throughput

0.316

High

976084

TNNC1
Troponin C, slow skeletal and cardiac muscles

1

0

High-throughput

0.282

High

976094

NTRK2
BDNF/NT-3 growth factors receptor

1

0

High-throughput

0.282

High

976110

NT2NA
Notch homolog 2 N-terminal-like protein A

1

0

High-throughput

0.282

High

976149

FNDC4
Fibronectin type III domain-containing protein 4

1

0

High-throughput

0.282

High

576100

CX6B1
Cytochrome c oxidase subunit 6B1

1

0

High-throughput

0.279

Low

646812

PUR6
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase

1

0

High-throughput

0.279

Low

976090

MOGS
Mannosyl-oligosaccharide glucosidase

1

0

High-throughput

0.279

Low

976122

F168A
Protein FAM168A

1

0

High-throughput

0.279

Low

976165

ASB6
Ankyrin repeat and SOCS box protein 6

1

0

High-throughput

0.279

Low

293507

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low

976097

DCA15
DDB1- and CUL4-associated factor 15

1

0

High-throughput

0.249

Low

838977

PK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

1

0

High-throughput

0.232

Low

976132

NEUL4
Neuralized-like protein 4

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025