HitPredict

Interactor 1: RAS1 (P08646)
Ras-like protein 1 (Dras1) (EC 3.6.5.2) (Dmras85D)
Gene: Ras85D

Interactor 2: Q9VCX2 (Q9VCX2)
Locomotion defects, isoform B
Gene: loco

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	1.00	0.590

Property	Details
Experiments	15710747
Identification Methods	two hybrid fragment pooling approach
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RBD~Ras
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 189 Dm			1 1175
+	Dm
		442973 RAP1_DROME (1-163): 2.09e-63: 195: 57.32		Q9VCX2_DROME (1-1175): 0: 1618: 100.00
+	Dm
		443010 RAS1_DROME (1-189): 6.58e-77: 229: 100.00		RGS_DROME (347-1175): 0: 997: 99.88
+	Dm
		442972 RAP1_DROME (1-163): 2.09e-63: 195: 57.32		RGS_DROME (347-1175): 0: 997: 99.88
+	Hs
		158596 RASH_HUMAN (1-181): 2.05e-92: 269: 81.22		RGS12_HUMAN (336-1116): 0: 670: 24.52
+	Rn
		139845 RASH_RAT (1-181): 2.05e-92: 269: 81.22		RGS12_RAT (336-1116): 0: 664: 25.36
+	Rn
		139848 RASN_RAT (1-170): 3.42e-90: 263: 83.53		RGS12_RAT (336-1116): 0: 664: 25.36
+	Hs
		207504 RASH_HUMAN (1-181): 2.05e-92: 269: 81.22		RGS14_HUMAN (417-927): 7.35e-169: 512: 28.41
+	Mm
		956619 RAB35_MOUSE (4-186): 2.5e-83: 246: 31.96		RGS14_MOUSE (417-927): 6.21e-167: 507: 29.25
+	Mm
		867148 RAB2A_MOUSE (4-179): 5.82e-75: 225: 30.90		RGS14_MOUSE (417-927): 6.21e-167: 507: 29.25
+	Mm
		918978 RAB1A_MOUSE (4-187): 2.22e-74: 224: 31.28		RGS14_MOUSE (417-927): 6.21e-167: 507: 29.25
+	Hs
		207516 RAP1A_HUMAN (1-165): 5.07e-62: 192: 55.69		RGS14_HUMAN (417-927): 7.35e-169: 512: 28.41
+	Hs
		782023 RAP1B_HUMAN (1-189): 6.47e-74: 222: 50.26		RGS2_HUMAN (410-581): 4.16e-60: 207: 27.22