HitPredict

Interactor 1: ITA5 (P08648)
Integrin alpha-5 (CD49 antigen-like family member E) (Fibronectin receptor subunit alpha) (Integrin alpha-F) (VLA-5) (CD antigen CD49e) [Cleaved into: Integrin alpha-5 heavy chain; Integrin alpha-5 light chain]
Gene: ITGA5

Interactor 2: RHOJ (Q9H4E5)
Rho-related GTP-binding protein RhoJ (Ras-like protein family member 7B) (Tc10-like GTP-binding protein)
Gene: RHOJ

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001525 - angiogenesis GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1049 Hs			1 214
+	Hs
		443060 ITA5_HUMAN (1-1049): 0: 1230: 100.00		CDC42_HUMAN (20-204): 2.24e-92: 270: 63.78
+	Hs
		443068 ITA5_HUMAN (1-1049): 0: 1230: 100.00		RAC1_HUMAN (22-214): 4.7e-82: 243: 57.51
+	Hs
		443063 ITA5_HUMAN (1-1049): 0: 1230: 100.00		RHOA_HUMAN (23-214): 1.09e-80: 240: 47.92
+	Hs
		436126 ITA5_HUMAN (1-1049): 0: 1230: 100.00		RHOC_HUMAN (23-214): 6.63e-79: 236: 48.44
+	Hs
		443028 ITA5_HUMAN (1-1049): 0: 1230: 100.00		RAC2_HUMAN (22-214): 1.98e-78: 235: 57.51
+	Hs
		443071 ITA5_HUMAN (1-1049): 0: 1230: 100.00		RHOG_HUMAN (20-214): 1.44e-78: 235: 50.26
+	Hs
		443030 ITA5_HUMAN (1-1049): 0: 1230: 100.00		RHOQ_HUMAN (22-213): 5.09e-77: 231: 79.49
+	Hs
		443059 ITA5_HUMAN (1-1049): 0: 1230: 100.00		RAC3_HUMAN (22-195): 2.97e-77: 231: 62.64
+	Hs
		443066 ITA5_HUMAN (1-1049): 0: 1230: 100.00		RHOB_HUMAN (23-214): 1.69e-76: 230: 48.44
+	Hs
		419185 ITAV_HUMAN (39-1028): 0: 1084: 45.89		CDC42_HUMAN (20-204): 2.24e-92: 270: 63.78
+	Hs
		419236 ITAV_HUMAN (39-1028): 0: 1084: 45.89		RHOJ_HUMAN (1-214): 2.19e-84: 250: 100.00
+	Hs
		419189 ITAV_HUMAN (39-1028): 0: 1084: 45.89		RAC1_HUMAN (22-214): 4.7e-82: 243: 57.51
+	Hs
		419186 ITAV_HUMAN (39-1028): 0: 1084: 45.89		RHOA_HUMAN (23-214): 1.09e-80: 240: 47.92
+	Hs
		419135 ITAV_HUMAN (39-1028): 0: 1084: 45.89		RHOC_HUMAN (23-214): 6.63e-79: 236: 48.44
+	Hs
		419149 ITAV_HUMAN (39-1028): 0: 1084: 45.89		RAC2_HUMAN (22-214): 1.98e-78: 235: 57.51
+	Hs
		419191 ITAV_HUMAN (39-1028): 0: 1084: 45.89		RHOG_HUMAN (20-214): 1.44e-78: 235: 50.26
+	Hs
		419150 ITAV_HUMAN (39-1028): 0: 1084: 45.89		RHOQ_HUMAN (22-213): 5.09e-77: 231: 79.49
+	Hs
		419184 ITAV_HUMAN (39-1028): 0: 1084: 45.89		RAC3_HUMAN (22-195): 2.97e-77: 231: 62.64
+	Hs
		419188 ITAV_HUMAN (39-1028): 0: 1084: 45.89		RHOB_HUMAN (23-214): 1.69e-76: 230: 48.44
+	Mm
		919010 ITA2B_MOUSE (14-1032): 0: 946: 37.03		RAB1A_MOUSE (12-210): 9.86e-79: 236: 22.50