HitPredict

Interactor 1: VIME (P08670)
Vimentin
Gene: VIM

Interactor 2: GRB2 (P62993)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	21988832
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 466 Hs			1 217
+	Hs
		409046 K2C8_HUMAN (79-461): 3.38e-139: 410: 35.51		GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00
+	Hs
		535366 GFAP_HUMAN (80-465): 2.56e-132: 390: 61.40		GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00
+	Hs
		924679 K2C73_HUMAN (5-414): 3.57e-91: 289: 32.10		GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00
+	Hs
		924469 KRT83_HUMAN (5-418): 1.39e-91: 288: 31.34		GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00
+	Hs
		924470 KRT85_HUMAN (3-418): 1.66e-91: 288: 32.32		GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00
+	Hs
		924576 KRT81_HUMAN (4-418): 4.08e-91: 287: 31.74		GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00
+	Hs
		213936 KRT86_HUMAN (4-418): 5.74e-90: 284: 31.74		GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00
+	Hs
		924895 KRT82_HUMAN (33-426): 1.42e-83: 268: 31.99		GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00
+	Hs
		924575 K1H2_HUMAN (5-417): 2.97e-76: 247: 26.44		GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00
+	Hs
		433246 DESM_HUMAN (9-465): 6.68e-138: 406: 62.20		YES_HUMAN (59-215): 4.17e-13: 69.2: 14.91
+	Hs
		569085 DESM_HUMAN (9-465): 6.68e-138: 406: 62.20		ITSN1_HUMAN (137-216): 1.36e-12: 68.1: 25.00
+	Hs
		924741 KRT35_HUMAN (8-426): 1.37e-75: 245: 27.25		GRB2_HUMAN (1-217): 6.71e-76: 229: 100.00
+	Hs
		411976 GFAP_HUMAN (80-465): 2.56e-132: 390: 61.40		FYN_HUMAN (161-215): 4.44e-14: 72.3: 31.58
+	Hs
		433235 GFAP_HUMAN (80-465): 2.56e-132: 390: 61.40		YES_HUMAN (59-215): 4.17e-13: 69.2: 14.91
+	Hs
		535403 GFAP_HUMAN (80-465): 2.56e-132: 390: 61.40		ITSN1_HUMAN (137-216): 1.36e-12: 68.1: 25.00
+	Hs
		275169 GFAP_HUMAN (80-465): 2.56e-132: 390: 61.40		GRAP2_HUMAN (3-55): 1.58e-10: 61.3: 39.62
+	Hs
		443382 VIME_HUMAN (14-466): 9.64e-116: 349: 100.00		ABL2_HUMAN (4-139): 9.61e-22: 94.7: 34.04
+	Hs
		422187 NFL_HUMAN (82-413): 4.58e-87: 278: 51.80		ITSN1_HUMAN (137-216): 1.36e-12: 68.1: 25.00
+	Hs
		422404 NFM_HUMAN (9-412): 5.26e-84: 278: 46.44		ITSN1_HUMAN (137-216): 1.36e-12: 68.1: 25.00
+	Hs
		442865 KRT35_HUMAN (8-426): 1.37e-75: 245: 27.25		HCK_HUMAN (120-215): 1.21e-12: 68.1: 19.39