Interactor 1: 5HT1A (P08908)
5-hydroxytryptamine receptor 1A (5-HT-1A) (5-HT1A) (G-21) (Serotonin receptor 1A)
Gene: HTR1A

Interactor 2: 5HT1D (P28221)
5-hydroxytryptamine receptor 1D (5-HT-1D) (5-HT1D) (Serotonin 1D alpha receptor) (5-HT-1D-alpha) (Serotonin receptor 1D)
Gene: HTR1D

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 11854302
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains 7tm_1~7tm_1
Common GO terms GO:0001588 - dopamine neurotransmitter receptor activity, coupled via Gs
GO:0004993 - G protein-coupled serotonin receptor activity
GO:0005886 - plasma membrane
GO:0007187 - G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
GO:0007198 - adenylate cyclase-inhibiting serotonin receptor signaling pathway
and 6 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 422
Hs

1 377
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Last updated: 15 Jul 2024