HitPredict

Interactor 1: NPM (P06748)
Nucleophosmin (NPM) (Nucleolar phosphoprotein B23) (Nucleolar protein NO38) (Numatrin)
Gene: NPM1

Interactor 2: HNRPU (Q00839)
Heterogeneous nuclear ribonucleoprotein U (hnRNP U) (GRIP120) (Nuclear p120 ribonucleoprotein) (Scaffold-attachment factor A) (SAF-A) (p120) (pp120)
Gene: HNRNPU

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

The method score is based on:

Property	Details
Experiments	26496610, 39501047, 20431927
Identification Methods	affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003682 - chromatin binding GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005813 - centrosome and 6 others more... GO:0005829 - cytosol GO:0016020 - membrane GO:0016607 - nuclear speck GO:0032991 - protein-containing complex GO:0045944 - positive regulation of transcription by RNA polymerase II GO:1990904 - ribonucleoprotein complex
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1	294
Hs

1	825

Service provided by Combinatics, Japan

Last updated: 11Aug2025