Interactor 1: ITB1 (P09055)
Integrin beta-1 (Fibronectin receptor subunit beta) (VLA-4 subunit beta) (CD antigen CD29)
Gene: Itgb1

Interactor 2: ITA6 (Q61739)
Integrin alpha-6 (CD49 antigen-like family member F) (VLA-6) (CD antigen CD49f) [Cleaved into: Integrin alpha-6 heavy chain; Integrin alpha-6 light chain; Processed integrin alpha-6 (Alpha6p)]
Gene: Itga6

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 1833411
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains EGF_2~Integrin_alpha2, I-EGF_1~Integrin_alpha2, Integrin_B_tail~Integrin_alpha2, Integrin_alpha2~Integrin_beta, Integrin_alpha2~PSI_integrin
Common GO terms GO:0005178 - integrin binding
GO:0005604 - basement membrane
GO:0005886 - plasma membrane
GO:0005912 - adherens junction
GO:0007160 - cell-matrix adhesion
and 13 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 798
Mm

1 1091
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024