HitPredict

Interactor 1: NPM (P06748)
Nucleophosmin (NPM) (Nucleolar phosphoprotein B23) (Nucleolar protein NO38) (Numatrin)
Gene: NPM1

Interactor 2: IKZF5 (Q9H5V7)
Zinc finger protein Pegasus (Ikaros family zinc finger protein 5)
Gene: IKZF5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0032991 - protein-containing complex
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 294 Hs			1 419
+	Hs
		446982 NPM_HUMAN (1-294): 1.76e-143: 406: 100.00		IKZF1_HUMAN (2-419): 3.39e-117: 353: 21.44
+	Hs
		447562 NPM_HUMAN (1-294): 1.76e-143: 406: 100.00		IKZF3_HUMAN (69-417): 4.06e-114: 345: 24.22
+	Hs
		446616 NPM_HUMAN (1-294): 1.76e-143: 406: 100.00		ZNF16_HUMAN (2-79): 1.9e-13: 74.3: 8.97
+	Hs
		446771 NPM_HUMAN (1-294): 1.76e-143: 406: 100.00		CTCF_HUMAN (82-161): 2.55e-10: 64.3: 37.50
+	Hs
		446965 NPM_HUMAN (1-294): 1.76e-143: 406: 100.00		REST_HUMAN (83-172): 5.64e-09: 60.5: 34.44
+	Hs
		288741 NPM3_HUMAN (10-119): 6.16e-58: 185: 43.75		ZN184_HUMAN (221-418): 8.01e-75: 249: 12.32
+	Hs
		288806 NPM3_HUMAN (10-119): 6.16e-58: 185: 43.75		ZN624_HUMAN (251-418): 5.5e-60: 211: 11.77
+	Hs
		288658 NPM3_HUMAN (10-119): 6.16e-58: 185: 43.75		ZKSC8_HUMAN (77-220): 5.68e-54: 190: 22.54
+	Hs
		288577 NPM3_HUMAN (10-119): 6.16e-58: 185: 43.75		ZNF16_HUMAN (2-79): 1.9e-13: 74.3: 8.97
+	Hs
		288603 NPM3_HUMAN (10-119): 6.16e-58: 185: 43.75		CTCF_HUMAN (82-161): 2.55e-10: 64.3: 37.50