Interactor 1: CDC6 (P09119)
Cell division control protein 6
Gene: CDC6

Interactor 2: ORC4 (P54791)
Origin recognition complex subunit 4 (Origin recognition complex 56 kDa subunit)
Gene: ORC4

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 1.00 0.912

The method score is based on:

Property Details
Experiments 9001208, 18647841, 26456755, 28191893, 35217664
Identification Methods coimmunoprecipitation, pull down, biochemical
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains AAA_22~ORC4_C
Common GO terms GO:0003688 - DNA replication origin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005656 - nuclear pre-replicative complex
GO:0006267 - pre-replicative complex assembly involved in nuclear cell cycle DNA replication
and 2 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 513
Sc

1 529
+ Sc
+ Hs
+ Hs
+ Sc
+ Hs
+ Hs
+ Sp
+ Dm
+ Dm
+ Sp
+ Dm
+ Sp
+ Sp
+ At
+ Sp
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024