Interactor 1: TOP2 (P06786)
DNA topoisomerase 2 (EC 5.6.2.2) (DNA topoisomerase II)
Gene: TOP2
Interactor 2: SMC6 (Q12749)
Structural maintenance of chromosomes protein 6 (DNA repair protein RHC18) (Rad18 homolog)
Gene: SMC6
Species: Saccharomyces cerevisiae S288C
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 0.60 | 0.479 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 26299966 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005739 - mitochondrion |
| Homologous interactions | 4 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
