HitPredict - High confidence protein-protein interactions

Interactor 1: MYC (P09416)
Myc proto-oncogene protein (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Interactor 2: MAX (P52164)
Protein max (Myc-associated factor X)
Gene: MAX

Species: Rattus norvegicus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	17304222
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	HLH~HLH, HLH~Myc-LZ
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific and 14 others more... GO:0003677 - DNA binding GO:0003700 - DNA-binding transcription factor activity GO:0005634 - nucleus GO:0006355 - regulation of DNA-templated transcription GO:0006357 - regulation of transcription by RNA polymerase II GO:0010629 - negative regulation of gene expression GO:0043565 - sequence-specific DNA binding GO:0044877 - protein-containing complex binding GO:0045893 - positive regulation of DNA-templated transcription GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0046983 - protein dimerization activity GO:0070888 - E-box binding GO:0071943 - Myc-Max complex GO:0140297 - DNA-binding transcription factor binding
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1	453
Rn

1	160

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024