Protein: ATX7
Ataxin-7 (Spinocerebellar ataxia type 7 protein)

Gene: ATX7, ATXN7
Organism: Homo sapiens
Interactions: 105
UniProt ID: O15265

Gene Ontology (top 5):
GO:0000124 - SAGA complex
GO:0000226 - microtubule cytoskeleton organization
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

184712

AT7L3
Ataxin-7-like protein 3

10

2

Small-scale

0.753

High

184735

KAT2A
Histone acetyltransferase KAT2A

9

20

Small-scale

0.748

High

184754

UBP22
Ubiquitin carboxyl-terminal hydrolase 22

7

10

Small-scale

0.748

High

184758

TRRAP
Transformation/transcription domain-associated protein

7

12

Small-scale

0.746

High

184715

TAF12
Transcription initiation factor TFIID subunit 12

5

4

Small-scale

0.718

High

184709

TAF10
Transcription initiation factor TFIID subunit 10

5

1

Small-scale

0.715

High

184731

SP20H
Transcription factor SPT20 homolog

4

2

Small-scale

0.694

High

184740

SGF29
SAGA-associated factor 29

4

2

Small-scale

0.694

High

184667

SUPT3
Transcription initiation protein SPT3 homolog

4

3

Small-scale

0.686

High

184759

TAF6L
TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L

3

2

High-throughput

0.675

High

184749

ENY2
Transcription and mRNA export factor ENY2

3

2

Small-scale

0.667

High

184668

TADA3
Transcriptional adapter 3

3

2

Small-scale

0.656

High

184660

CRX
Cone-rod homeobox protein

2

12

Small-scale

0.625

High

184669

TAF5L
TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L

2

9

Small-scale

0.611

High

184716

TAF9
Transcription initiation factor TFIID subunit 9

2

4

Small-scale

0.611

High

184724

TAD2B
Transcriptional adapter 2-beta

2

7

High-throughput

0.611

High

184666

TAD2A
Transcriptional adapter 2-alpha

2

8

Small-scale

0.584

High

184674

MYC
Myc proto-oncogene protein

2

11

High-throughput

0.584

High

184692

NUP62
Nuclear pore glycoprotein p62

1

6

High-throughput

0.573

High

184723

MEGF8
Multiple epidermal growth factor-like domains protein 8

1

11

High-throughput

0.573

High

184752

CEP72
Centrosomal protein of 72 kDa

1

2

High-throughput

0.573

High

184676

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

184696

TERA
Transitional endoplasmic reticulum ATPase

1

3

Small-scale

0.561

High

184744

SRBS1
Sorbin and SH3 domain-containing protein 1

1

17

Small-scale

0.554

High

184680

LAMB1
Laminin subunit beta-1

1

4

High-throughput

0.552

High

184699

PRS4
26S proteasome regulatory subunit 4

1

2

Small-scale

0.552

High

184726

SIAH1
E3 ubiquitin-protein ligase SIAH1

1

3

High-throughput

0.552

High

184757

NOC2L
Nucleolar complex protein 2 homolog

1

0

High-throughput

0.549

High

184671

ST65G
STAGA complex 65 subunit gamma

1

1

High-throughput

0.536

High

184714

SF3B3
Splicing factor 3B subunit 3

1

2

High-throughput

0.536

High

184736

KAT2B
Histone acetyltransferase KAT2B

1

16

High-throughput

0.536

High

184738

TADA1
Transcriptional adapter 1

1

1

High-throughput

0.536

High

184748

TAF9B
Transcription initiation factor TFIID subunit 9B

1

4

High-throughput

0.536

High

184728

LTBP4
Latent-transforming growth factor beta-binding protein 4

1

6

High-throughput

0.523

High

184682

H14
Histone H1.4

1

9

High-throughput

0.515

High

184729

RYBP
RING1 and YY1-binding protein

1

0

High-throughput

0.513

High

184661

SPY1
Protein sprouty homolog 1

1

1

High-throughput

0.508

High

184662

ACTN4
Alpha-actinin-4

1

7

High-throughput

0.508

High

184663

KALRN
Kalirin

1

4

High-throughput

0.508

High

184683

ACTN1
Alpha-actinin-1

1

7

High-throughput

0.508

High

184684

TRI27
Zinc finger protein RFP

1

3

High-throughput

0.508

High

184690

ACTN2
Alpha-actinin-2

1

7

High-throughput

0.508

High

184691

TRI23
E3 ubiquitin-protein ligase TRIM23

1

3

High-throughput

0.508

High

184695

RD23A
UV excision repair protein RAD23 homolog A

1

4

High-throughput

0.508

High

184697

LAMB2
Laminin subunit beta-2

1

5

High-throughput

0.508

High

184703

GOGA3
Golgin subfamily A member 3

1

7

High-throughput

0.508

High

184706

FBLN3
EGF-containing fibulin-like extracellular matrix protein 1

1

8

High-throughput

0.508

High

184711

ASPP2
Apoptosis-stimulating of p53 protein 2

1

11

High-throughput

0.508

High

184713

RABE1
Rab GTPase-binding effector protein 1

1

5

High-throughput

0.508

High

184717

GASP1
G-protein coupled receptor-associated sorting protein 1

1

2

High-throughput

0.508

High

184721

MPRIP
Myosin phosphatase Rho-interacting protein

1

6

High-throughput

0.508

High

184730

PNMA1
Paraneoplastic antigen Ma1

1

1

High-throughput

0.508

High

184732

CEP70
Centrosomal protein of 70 kDa

1

1

High-throughput

0.508

High

184739

RNF31
E3 ubiquitin-protein ligase RNF31

1

4

High-throughput

0.508

High

184745

TRI54
Tripartite motif-containing protein 54

1

14

High-throughput

0.508

High

184753

UBQL2
Ubiquilin-2

1

3

High-throughput

0.508

High

132950

MATN2
Matrilin-2

1

7

High-throughput

0.504

High

136745

AGRIN
Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment

1

2

High-throughput

0.504

High

184665

MEGF6
Multiple epidermal growth factor-like domains protein 6

1

6

High-throughput

0.504

High

184698

SUMO2
Small ubiquitin-related modifier 2

1

4

Small-scale

0.501

High

184700

SUMO1
Small ubiquitin-related modifier 1

1

4

Small-scale

0.501

High

184672

RAB3D
Ras-related protein Rab-3D

1

2

High-throughput

0.489

High

184686

ITPI2
Protein ITPRID2

1

0

High-throughput

0.486

High

184708

TRAF2
TNF receptor-associated factor 2

1

0

High-throughput

0.486

High

184720

LRSM1
E3 ubiquitin-protein ligase LRSAM1

1

0

High-throughput

0.486

High

184750

PICK1
PRKCA-binding protein

1

0

High-throughput

0.486

High

184710

SNX1
Sorting nexin-1

1

1

High-throughput

0.481

High

67113

UBP27
Ubiquitin carboxyl-terminal hydrolase 27

1

10

High-throughput

0.479

High

142721

NFIB
Nuclear factor 1 B-type

1

12

High-throughput

0.479

High

184664

PRKN
E3 ubiquitin-protein ligase parkin

1

9

High-throughput

0.479

High

184670

PIAS1
E3 SUMO-protein ligase PIAS1

1

3

Small-scale

0.479

High

184677

GCR
Glucocorticoid receptor

1

20

High-throughput

0.479

High

184681

NFIC
Nuclear factor 1 C-type

1

17

High-throughput

0.479

High

184688

PML
Protein PML

1

8

High-throughput

0.479

High

184693

HNF4A
Hepatocyte nuclear factor 4-alpha

1

20

High-throughput

0.479

High

184701

UBC9
SUMO-conjugating enzyme UBC9

1

3

Small-scale

0.479

High

184702

NC2B
Protein Dr1

1

1

High-throughput

0.479

High

184705

EP300
Histone acetyltransferase p300

1

16

Small-scale

0.479

High

184707

NFIA
Nuclear factor 1 A-type

1

16

High-throughput

0.479

High

184722

UBP51
Ubiquitin carboxyl-terminal hydrolase 51

1

14

High-throughput

0.479

High

184727

SLX4
Structure-specific endonuclease subunit SLX4

1

12

High-throughput

0.479

High

184734

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

184742

KLF6
Krueppel-like factor 6

1

9

High-throughput

0.479

High

184673

FBLN4
EGF-containing fibulin-like extracellular matrix protein 2

1

6

High-throughput

0.464

High

184675

FINC
Fibronectin

1

4

High-throughput

0.464

High

184679

VWF
von Willebrand factor

1

3

High-throughput

0.464

High

184689

FBN1
Fibrillin-1 [Cleaved into: Asprosin]

1

6

High-throughput

0.464

High

184704

GOGA2
Golgin subfamily A member 2

1

7

High-throughput

0.464

High

184719

TXD11
Thioredoxin domain-containing protein 11

1

2

High-throughput

0.464

High

184737

NELL1
Protein kinase C-binding protein NELL1

1

9

High-throughput

0.464

High

184741

NELL2
Protein kinase C-binding protein NELL2

1

9

High-throughput

0.464

High

184743

CAR10
Caspase recruitment domain-containing protein 10

1

5

High-throughput

0.464

High

184746

ADA33
Disintegrin and metalloproteinase domain-containing protein 33

1

6

High-throughput

0.464

High

184747

PP12C
Protein phosphatase 1 regulatory subunit 12C

1

12

High-throughput

0.464

High

184751

CRIM1
Cysteine-rich motor neuron 1 protein

1

7

High-throughput

0.464

High

184755

JAG2
Protein jagged-2

1

2

High-throughput

0.464

High

184685

TBP
TATA-box-binding protein

1

0

Small-scale

0.458

High

184694

MATR3
Matrin-3

1

0

High-throughput

0.458

High

184725

PALB2
Partner and localizer of BRCA2

1

0

Small-scale

0.458

High

184678

THY1
Thy-1 membrane glycoprotein

1

1

High-throughput

0.439

High

184718

AT7L2
Ataxin-7-like protein 2

1

1

High-throughput

0.437

High

72884

B0YJA4
Thy-1 membrane glycoprotein

1

1

High-throughput

0.417

High

184733

Q8TAS6
LAMB1 protein

1

6

High-throughput

0.417

High

184687

GRN
Progranulin

1

0

High-throughput

0.265

Low

184756

COG6
Conserved oligomeric Golgi complex subunit 6

1

0

High-throughput

0.265

Low


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Last updated: 11Aug2025