Protein: SUPT3
Transcription initiation protein SPT3 homolog (SPT3-like protein)

Gene: SUPT3, SUPT3H
Organism: Homo sapiens
Interactions: 58
UniProt ID: O75486

Gene Ontology (top 5):
GO:0000124 - SAGA complex
GO:0003713 - transcription coactivator activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006282 - regulation of DNA repair

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

283599

TAF10
Transcription initiation factor TFIID subunit 10

6

6

Small-scale

0.928

High

283619

SGF29
SAGA-associated factor 29

8

1

Small-scale

0.751

High

283584

TADA3
Transcriptional adapter 3

8

2

Small-scale

0.747

High

283615

KAT2A
Histone acetyltransferase KAT2A

9

6

Small-scale

0.747

High

283600

AT7L3
Ataxin-7-like protein 3

7

1

Small-scale

0.746

High

283635

TRRAP
Transformation/transcription domain-associated protein

7

3

Small-scale

0.743

High

283616

KAT2B
Histone acetyltransferase KAT2B

7

5

Small-scale

0.739

High

283604

TAF12
Transcription initiation factor TFIID subunit 12

6

6

Small-scale

0.730

High

283610

TAD2B
Transcriptional adapter 2-beta

6

4

Small-scale

0.730

High

283587

MYC
Myc proto-oncogene protein

5

1

Small-scale

0.717

High

283632

UBP22
Ubiquitin carboxyl-terminal hydrolase 22

5

3

Small-scale

0.714

High

283636

TAF6L
TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L

5

5

Small-scale

0.714

High

283585

TAF5L
TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L

5

6

Small-scale

0.709

High

283618

TADA1
Transcriptional adapter 1

5

1

Small-scale

0.709

High

184667

ATX7
Ataxin-7

4

3

Small-scale

0.686

High

283601

SF3B3
Splicing factor 3B subunit 3

4

2

Small-scale

0.686

High

283606

TAF9
Transcription initiation factor TFIID subunit 9

4

6

Small-scale

0.676

High

283586

ST65G
STAGA complex 65 subunit gamma

5

0

Small-scale

0.672

High

283612

SP20H
Transcription factor SPT20 homolog

4

0

Small-scale

0.657

High

130679

TAF4
Transcription initiation factor TFIID subunit 4

1

2

Small-scale

0.618

High

283622

SF3B5
Splicing factor 3B subunit 5

2

1

High-throughput

0.611

High

283403

TAD2A
Transcriptional adapter 2-alpha

2

4

Small-scale

0.584

High

283625

TAF9B
Transcription initiation factor TFIID subunit 9B

2

6

High-throughput

0.584

High

283626

ENY2
Transcription and mRNA export factor ENY2

2

1

High-throughput

0.584

High

283588

ESR1
Estrogen receptor

2

1

High-throughput

0.571

High

283605

DDB1
DNA damage-binding protein 1

1

2

Small-scale

0.561

High

283594

IMA5
Importin subunit alpha-5

1

0

High-throughput

0.513

High

283598

NOTC2
Neurogenic locus notch homolog protein 2

1

0

High-throughput

0.513

High

283591

TFE2
Transcription factor E2-alpha

1

0

Small-scale

0.480

High

283621

PYGO2
Pygopus homolog 2

1

0

Small-scale

0.480

High

67116

UBP27
Ubiquitin carboxyl-terminal hydrolase 27

1

3

High-throughput

0.479

High

283595

MAX
Protein max

1

1

Small-scale

0.479

High

283602

TAF5
Transcription initiation factor TFIID subunit 5

1

6

Small-scale

0.479

High

283613

DDB2
DNA damage-binding protein 2

1

2

Small-scale

0.479

High

283614

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

283631

YETS2
YEATS domain-containing protein 2

1

3

High-throughput

0.479

High

283633

WDR37
WD repeat-containing protein 37

1

2

High-throughput

0.479

High

283589

P53
Cellular tumor antigen p53

1

0

Small-scale

0.458

High

283593

BRCA2
Breast cancer type 2 susceptibility protein

1

0

Small-scale

0.458

High

283596

H4
Histone H4

1

0

High-throughput

0.458

High

283597

NC2B
Protein Dr1

1

0

High-throughput

0.458

High

283603

MED1
Mediator of RNA polymerase II transcription subunit 1

1

0

Small-scale

0.458

High

283609

EDC4
Enhancer of mRNA-decapping protein 4

1

0

High-throughput

0.458

High

283611

ZZZ3
ZZ-type zinc finger-containing protein 3

1

0

High-throughput

0.458

High

283617

MED12
Mediator of RNA polymerase II transcription subunit 12

1

0

Small-scale

0.458

High

283620

KLF6
Krueppel-like factor 6

1

0

High-throughput

0.458

High

283623

SP130
Histone deacetylase complex subunit SAP130

1

0

Small-scale

0.458

High

283624

CSR2B
Cysteine-rich protein 2-binding protein

1

0

High-throughput

0.458

High

283627

MBIP1
MAP3K12-binding inhibitory protein 1

1

0

High-throughput

0.458

High

283628

MED17
Mediator of RNA polymerase II transcription subunit 17

1

0

Small-scale

0.458

High

283629

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.458

High

283630

MED13
Mediator of RNA polymerase II transcription subunit 13

1

0

Small-scale

0.458

High

283634

MED16
Mediator of RNA polymerase II transcription subunit 16

1

0

Small-scale

0.458

High

283608

AT7L2
Ataxin-7-like protein 2

1

3

High-throughput

0.437

High

283607

H31T
Histone H3.1t

1

1

High-throughput

0.408

High

238983

ZNRD2
Protein ZNRD2

2

0

High-throughput

0.328

High

283590

CCL3
C-C motif chemokine 3

1

0

High-throughput

0.279

Low

283592

EFTU
Elongation factor Tu, mitochondrial

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025