HitPredict

Interactor 1: HMGB1 (P09429)
High mobility group protein B1 (High mobility group protein 1) (HMG-1)
Gene: HMGB1

Interactor 2: RAC1 (P63000)
Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (Cell migration-inducing gene 5 protein) (Ras-like protein TC25) (p21-Rac1)
Gene: RAC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	31980649, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006954 - inflammatory response
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 215 Hs			1 192
+	Hs
		70545 HGB1A_HUMAN (1-174): 4.91e-43: 145: 94.83		RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00
+	Hs
		175768 HMGB3_HUMAN (13-181): 1.02e-42: 144: 71.60		RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00
+	Hs
		449625 HMGB1_HUMAN (1-174): 9.92e-46: 152: 100.00		CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31
+	Hs
		817897 SOX2_HUMAN (3-94): 2.8e-25: 102: 23.91		RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00
+	Hs
		817864 SOX2_HUMAN (3-94): 2.8e-25: 102: 23.91		RHOA_HUMAN (5-192): 3.5e-77: 230: 57.98
+	Hs
		567665 UBF1_HUMAN (49-205): 2.54e-09: 58.2: 20.00		RAC3_HUMAN (1-191): 2.72e-79: 236: 93.19