HitPredict

Interactor 1: HMGB1 (P09429)
High mobility group protein B1 (High mobility group protein 1) (HMG-1)
Gene: HMGB1

Interactor 2: H2B1H (Q93079)
Histone H2B type 1-H (H2B-clustered histone 9) (Histone H2B.j) (H2B/j)
Gene: H2BC9

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37071682
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 215 Hs			1 126
+	Hs
		643380 HMGB2_HUMAN (1-187): 7e-43: 145: 82.89		H2B1H_HUMAN (1-126): 4.31e-55: 169: 100.00
+	Hs
		643248 HMGB2_HUMAN (1-187): 7e-43: 145: 82.89		H2B1B_HUMAN (1-126): 1.44e-54: 168: 96.83
+	Hs
		643302 HMGB2_HUMAN (1-187): 7e-43: 145: 82.89		H2B1C_HUMAN (1-126): 1.07e-54: 168: 99.21
+	Hs
		175767 HMGB3_HUMAN (13-181): 1.02e-42: 144: 71.60		H2B1C_HUMAN (1-126): 1.07e-54: 168: 99.21
+	Hs
		420830 SSRP1_HUMAN (53-164): 1.59e-28: 114: 37.50		H2B1J_HUMAN (1-126): 7.3e-55: 169: 97.62
+	Hs
		996694 SSRP1_HUMAN (53-164): 1.59e-28: 114: 37.50		H2B2E_HUMAN (1-126): 5.74e-55: 169: 98.41
+	Hs
		996812 SSRP1_HUMAN (53-164): 1.59e-28: 114: 37.50		H2B1H_HUMAN (1-126): 4.31e-55: 169: 100.00
+	Hs
		918316 SSRP1_HUMAN (53-164): 1.59e-28: 114: 37.50		H2B1C_HUMAN (1-126): 1.07e-54: 168: 99.21
+	Hs
		297497 TOX4_HUMAN (91-163): 1.19e-27: 111: 38.36		H2B2E_HUMAN (1-126): 5.74e-55: 169: 98.41
+	Hs
		996768 SSRP1_HUMAN (53-164): 1.59e-28: 114: 37.50		H2B3B_HUMAN (1-126): 1.45e-52: 163: 96.03
+	Hs
		996816 SSRP1_HUMAN (53-164): 1.59e-28: 114: 37.50		H2B1A_HUMAN (1-126): 1.15e-47: 151: 84.25
+	Hs
		707756 HM20A_HUMAN (64-204): 9.14e-16: 76.3: 25.69		H2B1B_HUMAN (1-126): 1.44e-54: 168: 96.83
+	Hs
		918706 HM20A_HUMAN (64-204): 9.14e-16: 76.3: 25.69		H2B1C_HUMAN (1-126): 1.07e-54: 168: 99.21
+	Ce
		136643 SSP1B_CAEEL (91-208): 5.6e-18: 83.7: 32.80		H2B1_CAEEL (8-126): 8.57e-50: 156: 80.67
+	Ce
		136714 SSP1B_CAEEL (91-208): 5.6e-18: 83.7: 32.80		H2B4_CAEEL (22-126): 8.35e-49: 153: 87.62
+	Sc
		355755 NHP6A_YEAST (75-164): 2.33e-23: 91.4: 45.56		H2B2_YEAST (3-125): 4.15e-41: 134: 71.55
+	Sc
		355756 NHP6B_YEAST (73-164): 1.14e-21: 87.1: 42.39		H2B2_YEAST (3-125): 4.15e-41: 134: 71.55
+	Sc
		355313 NHP6A_YEAST (75-164): 2.33e-23: 91.4: 45.56		H2B1_YEAST (4-125): 8.17e-37: 123: 72.13
+	Sc
		355314 NHP6B_YEAST (73-164): 1.14e-21: 87.1: 42.39		H2B1_YEAST (4-125): 8.17e-37: 123: 72.13
+	Sc
		355430 IXR1_YEAST (79-174): 6.78e-16: 77.4: 23.96		H2B1_YEAST (4-125): 8.17e-37: 123: 72.13