Protein: H2B1M
Histone H2B type 1-M (Histone H2B.e) (H2B/e)

Gene: H2B1M, H2BC14
Organism: Homo sapiens
Interactions: 102
UniProt ID: Q99879

Gene Ontology (top 5):
GO:0000786 - nucleosome
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

980215

H4
Histone H4

4

20

High-throughput

0.881

High

419167

H2A1B
Histone H2A type 1-B/E

3

20

High-throughput

0.839

High

591812

H2AX
Histone H2AX

3

20

Small-scale

0.839

High

1162020

H31T
Histone H3.1t

3

20

High-throughput

0.839

High

998737

H31
Histone H3.1

3

20

High-throughput

0.827

High

1163169

H2B2E
Histone H2B type 2-E

2

20

High-throughput

0.776

High

1372284

H2B1H
Histone H2B type 1-H

2

19

High-throughput

0.776

High

256970

H2B1K
Histone H2B type 1-K

2

20

High-throughput

0.754

High

508512

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

2

20

High-throughput

0.754

High

1408037

CHD8
Chromodomain-helicase-DNA-binding protein 8

1

20

High-throughput

0.691

High

334890

IPO7
Importin-7

1

13

High-throughput

0.665

High

649402

H1T
Histone H1t

1

20

High-throughput

0.665

High

1408008

H2A1J
Histone H2A type 1-J

1

20

High-throughput

0.665

High

1408039

HDAC6
Protein deacetylase HDAC6

1

20

High-throughput

0.665

High

449779

H2B1J
Histone H2B type 1-J

1

20

High-throughput

0.618

High

507339

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

1

20

High-throughput

0.618

High

634060

H2A1D
Histone H2A type 1-D

1

20

High-throughput

0.618

High

659938

H2B1O
Histone H2B type 1-O

1

20

High-throughput

0.618

High

754964

H2B1B
Histone H2B type 1-B

1

20

High-throughput

0.618

High

888283

MCM2
DNA replication licensing factor MCM2

1

20

High-throughput

0.618

High

943411

H2BFS
Histone H2B type F-S

1

19

High-throughput

0.618

High

946867

H2B1D
Histone H2B type 1-D

1

20

High-throughput

0.618

High

987175

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

1

20

High-throughput

0.618

High

987461

RL40
Ubiquitin-ribosomal protein eL40 fusion protein

1

20

High-throughput

0.618

High

1208881

H2B2F
Histone H2B type 2-F

1

20

High-throughput

0.618

High

1232722

H2A2A
Histone H2A type 2-A

1

20

High-throughput

0.618

High

1258927

H32
Histone H3.2

1

20

High-throughput

0.618

High

1272817

H2A3
Histone H2A type 3

1

20

High-throughput

0.618

High

1323967

H2B3B
Histone H2B type 3-B

1

19

High-throughput

0.618

High

1368085

HDAC2
Histone deacetylase 2

1

20

High-throughput

0.618

High

1380581

IGSF8
Immunoglobulin superfamily member 8

1

20

High-throughput

0.618

High

1399490

IPO9
Importin-9

1

15

High-throughput

0.618

High

1407988

H2B1N
Histone H2B type 1-N

1

20

High-throughput

0.618

High

1408028

H2B1L
Histone H2B type 1-L

1

20

High-throughput

0.618

High

422979

A4
Amyloid-beta precursor protein

2

2

High-throughput

0.602

High

372964

MYC
Myc proto-oncogene protein

1

9

High-throughput

0.575

High

1408030

COR1B
Coronin-1B

1

10

High-throughput

0.575

High

249775

DOK2
Docking protein 2

2

8

High-throughput

0.571

High

436721

KPCB
Protein kinase C beta type

2

20

High-throughput

0.571

High

440189

LCK
Tyrosine-protein kinase Lck

2

6

High-throughput

0.571

High

601831

HMGA1
High mobility group protein HMG-I/HMG-Y

2

15

High-throughput

0.571

High

702370

ELK4
ETS domain-containing protein Elk-4

2

12

High-throughput

0.571

High

987895

GRB2
Growth factor receptor-bound protein 2

2

18

High-throughput

0.571

High

1097159

MK07
Mitogen-activated protein kinase 7

2

11

High-throughput

0.571

High

1338757

ARI1B
AT-rich interactive domain-containing protein 1B

1

20

High-throughput

0.536

High

675649

TYY1
Transcriptional repressor protein YY1

1

12

High-throughput

0.515

High

1130964

BMS1
Ribosome biogenesis protein BMS1 homolog

1

6

High-throughput

0.515

High

1198203

PDCD4
Programmed cell death protein 4

1

8

High-throughput

0.515

High

1211586

C2D1B
Coiled-coil and C2 domain-containing protein 1B

1

20

High-throughput

0.515

High

1275898

TICRR
Treslin

1

20

High-throughput

0.515

High

1400785

ATAD5
ATPase family AAA domain-containing protein 5

1

20

High-throughput

0.515

High

1403101

OSBL9
Oxysterol-binding protein-related protein 9

1

6

High-throughput

0.515

High

1270962

RHOU
Rho-related GTP-binding protein RhoU

1

1

High-throughput

0.501

High

261921

PP1RB
E3 ubiquitin-protein ligase PPP1R11

1

0

High-throughput

0.493

High

1408035

SPEF2
Sperm flagellar protein 2

1

0

High-throughput

0.493

High

1408038

IFT57
Intraflagellar transport protein 57 homolog

1

0

High-throughput

0.493

High

137476

HMGN4
High mobility group nucleosome-binding domain-containing protein 4

1

20

High-throughput

0.479

High

138289

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

13

High-throughput

0.479

High

141069

NOP56
Nucleolar protein 56

1

5

Small-scale

0.479

High

187167

PPM1G
Protein phosphatase 1G

1

11

High-throughput

0.479

High

325076

HEXI1
Protein HEXIM1

1

14

High-throughput

0.479

High

349217

LATS1
Serine/threonine-protein kinase LATS1

1

20

High-throughput

0.479

High

426564

HMGN2
Non-histone chromosomal protein HMG-17

1

20

High-throughput

0.479

High

427932

ICAM1
Intercellular adhesion molecule 1

1

20

High-throughput

0.479

High

552365

ADT3
ADP/ATP translocase 3

1

5

High-throughput

0.479

High

565459

ITA4
Integrin alpha-4

1

7

High-throughput

0.479

High

568170

PLSL
Plastin-2

1

8

High-throughput

0.479

High

568282

PLST
Plastin-3

1

8

High-throughput

0.479

High

607048

CEBPB
CCAAT/enhancer-binding protein beta

1

3

High-throughput

0.479

High

630012

BTF3
Transcription factor BTF3

1

11

High-throughput

0.479

High

756033

MCM5
DNA replication licensing factor MCM5

1

20

High-throughput

0.479

High

861265

MAP1B
Microtubule-associated protein 1B

1

20

High-throughput

0.479

High

947265

NLRP6
NACHT, LRR and PYD domains-containing protein 6

1

3

High-throughput

0.479

High

948917

CD81
CD81 antigen

1

11

High-throughput

0.479

High

1008854

RED1
Double-stranded RNA-specific editase 1

1

14

High-throughput

0.479

High

1151432

HMGN3
High mobility group nucleosome-binding domain-containing protein 3

1

14

High-throughput

0.479

High

1194324

LARP7
La-related protein 7

1

20

High-throughput

0.479

High

1211612

TEX35
Testis-expressed protein 35

1

12

High-throughput

0.479

High

1214856

ARM12
Armadillo repeat-containing protein 12

1

1

Small-scale

0.479

High

1271816

MEPCE
7SK snRNA methylphosphate capping enzyme

1

14

High-throughput

0.479

High

1281596

SLN11
Schlafen family member 11

1

3

High-throughput

0.479

High

1308478

VRK3
Serine/threonine-protein kinase VRK3

1

11

High-throughput

0.479

High

1313374

SMC5
Structural maintenance of chromosomes protein 5

1

16

High-throughput

0.479

High

1334829

SERB1
SERPINE1 mRNA-binding protein 1

1

12

High-throughput

0.479

High

1397357

CI072
Guanine nucleotide exchange factor C9orf72

1

6

High-throughput

0.479

High

1408029

VRK1
Serine/threonine-protein kinase VRK1

1

6

High-throughput

0.479

High

1408031

RIOK1
Serine/threonine-protein kinase RIO1

1

12

High-throughput

0.479

High

1408033

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

20

High-throughput

0.479

High

1408034

ACE2
Angiotensin-converting enzyme 2

1

4

Small-scale

0.479

High

1408036

SPRTN
DNA-dependent metalloprotease SPRTN

1

8

Small-scale

0.479

High

1408042

TMA7
Translation machinery-associated protein 7

1

4

High-throughput

0.470

High

1408032

MSTO1
Protein misato homolog 1

1

0

High-throughput

0.458

High

530285

TAU
Microtubule-associated protein tau

1

20

High-throughput

0.445

High

1134696

NUMA1
Nuclear mitotic apparatus protein 1

1

20

High-throughput

0.445

High

1255246

TRI67
Tripartite motif-containing protein 67

1

15

High-throughput

0.437

High

1291567

HOOK3
Protein Hook homolog 3

1

20

High-throughput

0.437

High

1324062

RHG24
Rho GTPase-activating protein 24

1

15

High-throughput

0.437

High

1408041

TENN
Tenascin-N

1

20

High-throughput

0.437

High

1408040

PPM1H
Protein phosphatase 1H

1

0

Small-scale

0.426

High

303711

CYTF
Cystatin-F

1

0

High-throughput

0.269

Low

641998

MATN1
Matrilin-1

1

0

High-throughput

0.269

Low

1281402

COXM1
COX assembly mitochondrial protein homolog

1

0

High-throughput

0.269

Low


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Last updated: 11Aug2025