HitPredict

Interactor 1: HSP73 (P09435)
Heat shock protein SSA3
Gene: SSA3

Interactor 2: HRD1 (Q08109)
ERAD-associated E3 ubiquitin-protein ligase HRD1 (EC 2.3.2.27) (HMG-CoA reductase degradation protein 1) (RING-type E3 ubiquitin transferase HRD1)
Gene: HRD1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	19536198
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 649 Sc			1 551
+	Sc
		495120 HSP72_YEAST (1-649): 0: 941: 78.89		HRD1_YEAST (1-551): 2.26e-158: 464: 100.00
+	Sc
		492627 HSP71_YEAST (1-649): 0: 939: 79.35		HRD1_YEAST (1-551): 2.26e-158: 464: 100.00
+	Hs
		504330 HSP7C_HUMAN (2-649): 0: 946: 72.53		SYVN1_HUMAN (7-481): 1.31e-90: 292: 20.63
+	Hs
		714092 HS71L_HUMAN (2-649): 0: 958: 70.06		AMFR_HUMAN (41-477): 3.96e-54: 195: 15.82
+	Hs
		713994 HS71L_HUMAN (2-649): 0: 958: 70.06		RNF43_HUMAN (221-519): 3.36e-35: 142: 11.44
+	Hs
		564092 HSP76_HUMAN (4-649): 0: 950: 70.43		RNF43_HUMAN (221-519): 3.36e-35: 142: 11.44
+	Hs
		504235 HSP7C_HUMAN (2-649): 0: 946: 72.53		RNF43_HUMAN (221-519): 3.36e-35: 142: 11.44
+	Hs
		714011 HS71L_HUMAN (2-649): 0: 958: 70.06		GOLI_HUMAN (273-483): 1.19e-30: 125: 17.84
+	Sc
		493226 HSP72_YEAST (1-649): 0: 941: 78.89		SAN1_YEAST (325-521): 3.77e-31: 129: 14.93
+	Hs
		871613 HSP72_HUMAN (2-610): 0: 927: 74.63		RNF43_HUMAN (221-519): 3.36e-35: 142: 11.44
+	Sc
		490368 HSP71_YEAST (1-649): 0: 939: 79.35		SAN1_YEAST (325-521): 3.77e-31: 129: 14.93
+	Sc
		495048 HSP72_YEAST (1-649): 0: 941: 78.89		IRC20_YEAST (133-437): 2.76e-29: 125: 11.73
+	Sc
		492538 HSP71_YEAST (1-649): 0: 939: 79.35		IRC20_YEAST (133-437): 2.76e-29: 125: 11.73
+	Sp
		195220 HSP72_SCHPO (1-649): 0: 927: 77.20		DSC1_SCHPO (189-404): 2.98e-29: 124: 20.00