Interactor 1: TY3H (P07101)
Tyrosine 3-monooxygenase (EC 1.14.16.2) (Tyrosine 3-hydroxylase) (TH)
Gene: TH
Interactor 2: TY3H (P07101)
Tyrosine 3-monooxygenase (EC 1.14.16.2) (Tyrosine 3-hydroxylase) (TH)
Gene: TH
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.62 | 1.00 | 0.794 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 32296183, unassigned1304 |
| Identification Methods | two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid, mammalian protein protein interaction trap |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Biopterin_H~Biopterin_H, TH_ACT~TH_ACT |
| Common GO terms | GO:0001666 - response to hypoxia GO:0001963 - synaptic transmission, dopaminergic GO:0003007 - heart morphogenesis GO:0004511 - tyrosine 3-monooxygenase activity GO:0005506 - iron ion binding and 32 others more... |
| Homologous interactions | 3 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
