HitPredict

Interactor 1: C1TM (P09440)
C-1-tetrahydrofolate synthase, mitochondrial (C1-THF synthase) [Includes: Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9); Formyltetrahydrofolate synthetase (EC 6.3.4.3)]
Gene: MIS1

Interactor 2: SSB1 (P11484)
Ribosome-associated molecular chaperone SSB1 (EC 3.6.4.10) (Cold-inducible protein YG101) (Heat shock protein SSB1) (Hsp70 chaperone Ssb)
Gene: SSB1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	19536198, 16429126
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 975 Sc			1 613
+	Sc
		450448 C1TM_YEAST (13-975): 0: 1531: 100.00		SSB2_YEAST (1-613): 0: 1118: 99.35
+	Sc
		423502 C1TC_YEAST (36-975): 0: 1439: 71.10		SSB1_YEAST (1-613): 0: 1128: 100.00
+	Sc
		423528 C1TC_YEAST (36-975): 0: 1439: 71.10		SSB2_YEAST (1-613): 0: 1118: 99.35
+	Hs
		503329 C1TC_HUMAN (32-975): 0: 1529: 55.64		HSP7C_HUMAN (5-612): 0: 900: 59.84
+	Hs
		504269 C1TM_HUMAN (42-975): 0: 1393: 48.61		HSP7C_HUMAN (5-612): 0: 900: 59.84
+	Sc
		449867 C1TM_YEAST (13-975): 0: 1531: 100.00		HSP73_YEAST (9-611): 0: 677: 60.66
+	Sc
		512389 MTD1_YEAST (42-329): 3.11e-62: 216: 24.17		SSB1_YEAST (1-613): 0: 1128: 100.00
+	Hs
		503354 MTDC_HUMAN (21-329): 2.55e-127: 391: 42.95		HSP7C_HUMAN (5-612): 0: 900: 59.84