HitPredict

Interactor 1: CLCA (P09496)
Clathrin light chain A (Lca)
Gene: CLTA

Interactor 2: AP1S1 (P61966)
AP-1 complex subunit sigma-1A (Adaptor protein complex AP-1 subunit sigma-1A) (Adaptor-related protein complex 1 subunit sigma-1A) (Clathrin assembly protein complex 1 sigma-1A small chain) (Clathrin coat assembly protein AP19) (Golgi adaptor HA1/AP1 adaptin sigma-1A subunit) (HA1 19 kDa subunit) (Sigma 1a subunit of AP-1 clathrin) (Sigma-adaptin 1A) (Sigma1A-adaptin)
Gene: AP1S1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0006886 - intracellular protein transport GO:0016020 - membrane GO:0032588 - trans-Golgi network membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 248 Hs			1 158
+	Hs
		451407 CLCA_HUMAN (1-248): 1.53e-98: 289: 100.00		AP1S2_HUMAN (2-157): 6.27e-54: 169: 87.82
+	Hs
		451529 CLCA_HUMAN (1-248): 1.53e-98: 289: 100.00		AP2M1_HUMAN (1-158): 6.58e-47: 159: 16.98
+	Hs
		451547 CLCA_HUMAN (1-248): 1.53e-98: 289: 100.00		AP1M1_HUMAN (3-154): 3.03e-45: 154: 18.07
+	Hs
		451400 CLCA_HUMAN (1-248): 1.53e-98: 289: 100.00		AP2S1_HUMAN (1-142): 3.82e-44: 143: 44.37
+	Hs
		451718 CLCB_HUMAN (35-247): 1.52e-67: 210: 60.28		AP2M1_HUMAN (1-158): 6.58e-47: 159: 16.98
+	Hs
		451725 CLCB_HUMAN (35-247): 1.52e-67: 210: 60.28		AP1M1_HUMAN (3-154): 3.03e-45: 154: 18.07
+	Hs
		451654 CLCB_HUMAN (35-247): 1.52e-67: 210: 60.28		AP2S1_HUMAN (1-142): 3.82e-44: 143: 44.37