HitPredict

Interactor 1: CLCA (P09496)
Clathrin light chain A (Lca)
Gene: CLTA

Interactor 2: ITSN1 (Q15811)
Intersectin-1 (SH3 domain-containing protein 1A) (SH3P17)
Gene: ITSN1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

Property	Details
Experiments	32203420, 34079125, unassigned2213
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 248 Hs			1 1721
+	Hs
		451680 CLCB_HUMAN (35-247): 1.52e-67: 210: 60.28		ITSN1_HUMAN (1-1721): 0: 897: 100.00
+	Hs
		451583 CLCA_HUMAN (1-248): 1.53e-98: 289: 100.00		ITSN2_HUMAN (1-1720): 0: 723: 54.73
+	Hs
		451745 CLCB_HUMAN (35-247): 1.52e-67: 210: 60.28		ITSN2_HUMAN (1-1720): 0: 723: 54.73
+	Hs
		451349 CLCA_HUMAN (1-248): 1.53e-98: 289: 100.00		BCR_HUMAN (732-1682): 1.5e-71: 266: 12.45
+	Hs
		451574 CLCA_HUMAN (1-248): 1.53e-98: 289: 100.00		ARHG4_HUMAN (1063-1635): 4.45e-74: 264: 15.77
+	Hs
		451587 CLCA_HUMAN (1-248): 1.53e-98: 289: 100.00		EP15R_HUMAN (545-929): 2.95e-11: 70.8: 14.14
+	Hs
		451386 CLCA_HUMAN (1-248): 1.53e-98: 289: 100.00		EPS15_HUMAN (529-913): 1.04e-10: 68.9: 12.69
+	Hs
		451460 CLCA_HUMAN (1-248): 1.53e-98: 289: 100.00		SH319_HUMAN (1079-1218): 3.12e-09: 63.9: 28.57
+	Hs
		451645 CLCB_HUMAN (35-247): 1.52e-67: 210: 60.28		EPS15_HUMAN (529-913): 1.04e-10: 68.9: 12.69
+	Hs
		451685 CLCB_HUMAN (35-247): 1.52e-67: 210: 60.28		SH319_HUMAN (1079-1218): 3.12e-09: 63.9: 28.57
+	Ce
		954169 P90961_CAEEL (30-244): 4.57e-32: 118: 24.31		Q9U2T9_CAEEL (708-1241): 6.47e-10: 66.6: 11.25