Interactor 1: PGFRB (P09619)
Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta platelet-derived growth factor receptor) (Beta-type platelet-derived growth factor receptor) (CD140 antigen-like family member B) (Platelet-derived growth factor receptor 1) (PDGFR-1) (CD antigen CD140b)
Gene: PDGFRB

Interactor 2: PDGFC (Q9NRA1)
Platelet-derived growth factor C (PDGF-C) (Fallotein) (Spinal cord-derived growth factor) (SCDGF) (VEGF-E) [Cleaved into: Platelet-derived growth factor C, latent form (PDGFC latent form); Platelet-derived growth factor C, receptor-binding form (PDGFC receptor-binding form)]
Gene: PDGFC

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 11297552
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PDGF~ig, Ig_3~PDGF
Common GO terms GO:0005161 - platelet-derived growth factor receptor binding
GO:0005634 - nucleus
GO:0005886 - plasma membrane
GO:0008284 - positive regulation of cell population proliferation
GO:0030335 - positive regulation of cell migration
and 2 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 1106
Hs

1 345
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Last updated: 15 Jul 2024