Interactor 1: DLDH (P09624)
Dihydrolipoyl dehydrogenase, mitochondrial (DLD) (EC 1.8.1.4) (2-oxoglutarate dehydrogenase complex component E3) (OGDC-E3) (OGDHC subunit E3) (Alpha-ketoglutarate dehydrogenase complex subunit E3) (alpha-KGDHC subunit E3) (Dihydrolipoamide dehydrogenase) (Dihydrolipoamide:NAD(+) oxidoreductase) (Glycine decarboxylase complex subunit L) (GDC subunit L) (Lipoamide dehydrogenase component of pyruvate dehydrogenase complex) (Pyruvate dehydrogenase complex E3 component) (PDC subunit E3) (PDH complex subunit E3)
Gene: LPD1

Interactor 2: ODO1 (P20967)
2-oxoglutarate dehydrogenase, mitochondrial (OGDH) (EC 1.2.4.2) (2-oxoglutarate dehydrogenase complex component E1) (OGDC-E1) (OGDHC subunit E1) (Alpha-ketoglutarate dehydrogenase complex subunit E1) (alpha-KGDHC subunit E1)
Gene: KGD1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 0.60 0.716

The method score is based on:

Property Details
Experiments 11805826, 16429126, 25165143, 37968396, 32051233
Identification Methods tandem affinity purification, affinity chromatography technology, cross-linking study, pull down
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0004591 - oxoglutarate dehydrogenase (succinyl-transferring) activity
GO:0005739 - mitochondrion
GO:0006103 - 2-oxoglutarate metabolic process
GO:0042645 - mitochondrial nucleoid
GO:0045252 - oxoglutarate dehydrogenase complex
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 499
Sc

1 1014
+ Hs
+ Hs
+ Hs
+ Ec
+ Sc
+ Hs
+ At

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Last updated: 15 Jul 2024