Protein: SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial (EC 1.3.5.1) (Flavoprotein subunit of complex II) (FP)

Gene: SDHA, SDH1
Organism: Saccharomyces cerevisiae S288C
Interactions: 47
UniProt ID: Q00711

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0006099 - tricarboxylic acid cycle
GO:0006121 - mitochondrial electron transport, succinate to ubiquinone
GO:0008177 - succinate dehydrogenase (quinone) activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

641106

SDHB
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial

4

7

Small-scale

0.873

High

1026930

SDHF2
Succinate dehydrogenase assembly factor 2, mitochondrial

3

1

Small-scale

0.839

High

790389

DHSD
Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial

3

0

Small-scale

0.784

High

510730

HSP77
Import motor subunit, mitochondrial

3

1

High-throughput

0.640

High

734785

NDI1
Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial

1

0

High-throughput

0.586

High

798523

SDHF4
Succinate dehydrogenase assembly factor 4, mitochondrial

1

0

Small-scale

0.586

High

452953

ATPA
ATP synthase subunit alpha, mitochondrial

2

3

High-throughput

0.584

High

781442

MIC60
MICOS complex subunit MIC60

2

1

High-throughput

0.584

High

1026932

SDHF1
Succinate dehydrogenase assembly factor 1, mitochondrial

2

1

Small-scale

0.584

High

796254

TCM62
Mitochondrial chaperone TCM62

1

7

Small-scale

0.561

High

393179

HSP82
ATP-dependent molecular chaperone HSP82

2

3

High-throughput

0.521

High

671019

SIS1
Protein SIS1

2

2

High-throughput

0.521

High

1026929

FRDA
Frataxin homolog, mitochondrial

1

1

Small-scale

0.515

High

367099

ATPB
ATP synthase subunit beta, mitochondrial

1

3

High-throughput

0.479

High

432028

ATPF
ATP synthase subunit 4, mitochondrial

1

1

High-throughput

0.479

High

453303

QCR2
Cytochrome b-c1 complex subunit 2, mitochondrial

1

4

High-throughput

0.479

High

598336

HEMH
Ferrochelatase, mitochondrial

1

1

High-throughput

0.479

High

604971

MDHM
Malate dehydrogenase, mitochondrial

1

5

Small-scale

0.479

High

626854

HSP60
Heat shock protein 60, mitochondrial

1

6

High-throughput

0.479

High

679970

CDC48
Cell division control protein 48

1

1

High-throughput

0.479

High

739443

ZUO1
Zuotin

1

2

Small-scale

0.479

High

752612

HSP78
Heat shock protein 78, mitochondrial

1

5

High-throughput

0.479

High

785956

LONM
Lon protease homolog, mitochondrial

1

2

High-throughput

0.479

High

881416

TOM22
Mitochondrial import receptor subunit TOM22

1

2

High-throughput

0.479

High

1026928

SDHF3
Succinate dehydrogenase assembly factor 3, mitochondrial

1

1

Small-scale

0.479

High

1026931

SMC6
Structural maintenance of chromosomes protein 6

1

2

High-throughput

0.479

High

360902

COX6
Cytochrome c oxidase subunit 6, mitochondrial

1

0

High-throughput

0.458

High

417164

VDAC1
Non-selective voltage-gated ion channel 1

1

0

High-throughput

0.458

High

673523

STDH
Catabolic L-serine/threonine dehydratase [Includes: L-serine dehydratase

1

0

High-throughput

0.458

High

737183

ACPM
Acyl carrier protein, mitochondrial

1

0

High-throughput

0.458

High

746913

TIM23
Mitochondrial import inner membrane translocase subunit TIM23

1

0

High-throughput

0.458

High

753176

SDH3
Succinate dehydrogenase [ubiquinone] cytochrome b subunit, mitochondrial

1

0

High-throughput

0.458

High

812203

ILV3
Dihydroxy-acid dehydratase, mitochondrial

1

0

High-throughput

0.458

High

818633

FMP10
Uncharacterized mitochondrial membrane protein FMP10

1

0

High-throughput

0.458

High

856557

ALDH4
Potassium-activated aldehyde dehydrogenase, mitochondrial

1

0

High-throughput

0.458

High

865834

AIM24
Altered inheritance of mitochondria protein 24, mitochondrial

1

0

High-throughput

0.458

High

1026927

RCF1
Respiratory supercomplex factor 1, mitochondrial

1

0

Small-scale

0.458

High

509683

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

1

High-throughput

0.457

High

923103

BRE5
UBP3-associated protein BRE5

1

1

High-throughput

0.445

High

512590

RS6A
Small ribosomal subunit protein eS6A

1

1

High-throughput

0.437

High

558833

CAF20
Cap-associated protein CAF20

1

1

High-throughput

0.437

High

707913

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

442058

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.249

Low

747997

SMY2
Protein SMY2

1

0

High-throughput

0.249

Low

758044

MTR2
mRNA transport regulator MTR2

1

0

High-throughput

0.249

Low

918426

EIF2A
Eukaryotic translation initiation factor 2A

1

0

High-throughput

0.249

Low

792909

ANM1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025