HitPredict

Interactor 1: ROA1 (P09651)
Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) (Helix-destabilizing protein) (Single-strand RNA-binding protein) (hnRNP core protein A1) [Cleaved into: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed]
Gene: HNRNPA1

Interactor 2: IFIT2 (P09913)
Interferon-induced protein with tetratricopeptide repeats 2 (IFIT-2) (ISG-54 K) (Interferon-induced 54 kDa protein) (IFI-54K) (P54)
Gene: IFIT2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	21642987
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 372 Hs			1 472
+	Hs
		161943 HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41		IFIT2_HUMAN (1-472): 1.93e-109: 334: 100.00
+	Hs
		456208 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		IFIT2_HUMAN (1-472): 1.93e-109: 334: 100.00
+	Hs
		157414 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		IFIT3_HUMAN (1-471): 1.24e-97: 304: 55.93
+	Hs
		157394 HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41		IFIT3_HUMAN (1-471): 1.24e-97: 304: 55.93
+	Hs
		157426 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		IFIT3_HUMAN (1-471): 1.24e-97: 304: 55.93
+	Hs
		157433 ROA3_HUMAN (7-202): 5.98e-55: 186: 85.71		IFIT3_HUMAN (1-471): 1.24e-97: 304: 55.93
+	Hs
		456243 ROAA_HUMAN (6-184): 1.25e-35: 134: 39.44		IFIT2_HUMAN (1-472): 1.93e-109: 334: 100.00
+	Hs
		157469 ROAA_HUMAN (6-184): 1.25e-35: 134: 39.44		IFIT3_HUMAN (1-471): 1.24e-97: 304: 55.93
+	Hs
		456228 HNRPD_HUMAN (2-101): 4.8e-18: 86.4: 31.00		IFIT2_HUMAN (1-472): 1.93e-109: 334: 100.00
+	Hs
		157451 HNRPD_HUMAN (2-101): 4.8e-18: 86.4: 31.00		IFIT3_HUMAN (1-471): 1.24e-97: 304: 55.93
+	Hs
		157449 PABP4_HUMAN (102-190): 3.52e-15: 79: 15.56		IFIT3_HUMAN (1-471): 1.24e-97: 304: 55.93
+	Hs
		174568 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		OGT1_HUMAN (23-298): 3.87e-37: 147: 17.03
+	Hs
		175106 DAZP1_HUMAN (8-365): 1.46e-57: 194: 24.87		OGT1_HUMAN (23-298): 3.87e-37: 147: 17.03
+	Hs
		161904 HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41		OGT1_HUMAN (23-298): 3.87e-37: 147: 17.03
+	Hs
		174624 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		OGT1_HUMAN (23-298): 3.87e-37: 147: 17.03
+	Sc
		376611 PABP_YEAST (4-189): 6.12e-39: 147: 24.47		CYC8_YEAST (167-471): 3.46e-33: 135: 10.64
+	Hs
		175138 ROAA_HUMAN (6-184): 1.25e-35: 134: 39.44		OGT1_HUMAN (23-298): 3.87e-37: 147: 17.03
+	Hs
		174877 HNRPD_HUMAN (2-101): 4.8e-18: 86.4: 31.00		OGT1_HUMAN (23-298): 3.87e-37: 147: 17.03
+	Hs
		174849 PABP4_HUMAN (102-190): 3.52e-15: 79: 15.56		OGT1_HUMAN (23-298): 3.87e-37: 147: 17.03
+	Sc
		376753 PABP_YEAST (4-189): 6.12e-39: 147: 24.47		CDC27_YEAST (318-471): 4.22e-10: 64.1: 12.96