Protein: TRIB1
Tribbles homolog 1 (TRB-1) (G-protein-coupled receptor-induced gene 2 protein) (GIG-2) (SKIP1)

Gene: TRIB1
Organism: Homo sapiens
Interactions: 41
UniProt ID: Q96RU8

Gene Ontology (top 5):
GO:0004860 - protein kinase inhibitor activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006469 - negative regulation of protein kinase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1231636

STK40
Serine/threonine-protein kinase 40

5

19

High-throughput

0.930

High

1266262

TRIB2
Tribbles homolog 2

2

17

High-throughput

0.811

High

1246150

COP1
E3 ubiquitin-protein ligase COP1

8

12

Small-scale

0.755

High

295822

ST17B
Serine/threonine-protein kinase 17B

1

19

High-throughput

0.691

High

1082345

DDB1
DNA damage-binding protein 1

1

7

High-throughput

0.691

High

1104170

RA1L2
Heterogeneous nuclear ribonucleoprotein A1-like 2

1

12

High-throughput

0.691

High

1185081

DET1
DET1 homolog

3

3

High-throughput

0.675

High

548326

FOSL2
Fos-related antigen 2

3

17

High-throughput

0.667

High

851876

UB2E1
Ubiquitin-conjugating enzyme E2 E1

2

5

High-throughput

0.628

High

1301577

ISCA1
Iron-sulfur cluster assembly 1 homolog, mitochondrial

2

3

High-throughput

0.628

High

1301578

PECR
Peroxisomal trans-2-enoyl-CoA reductase

2

1

High-throughput

0.628

High

1301583

MALT1
Mucosa-associated lymphoid tissue lymphoma translocation protein 1

2

4

High-throughput

0.628

High

831614

CEBPA
CCAAT/enhancer-binding protein alpha

2

9

Small-scale

0.619

High

345527

FOS
Protein c-Fos

2

16

High-throughput

0.618

High

800996

MP2K4
Dual specificity mitogen-activated protein kinase kinase 4

1

19

Small-scale

0.618

High

972242

MP2K1
Dual specificity mitogen-activated protein kinase kinase 1

1

19

Small-scale

0.618

High

1301576

TRIB1
Tribbles homolog 1

1

16

Small-scale

0.575

High

569980

CEBPB
CCAAT/enhancer-binding protein beta

2

11

Small-scale

0.545

High

63695

TSPY2
Testis-specific Y-encoded protein 2

1

3

High-throughput

0.536

High

238068

PDE8A
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A

1

10

High-throughput

0.536

High

548261

FOSL1
Fos-related antigen 1

1

15

High-throughput

0.536

High

566786

JUNB
Transcription factor JunB

1

9

High-throughput

0.536

High

579370

ATF6A
Cyclic AMP-dependent transcription factor ATF-6 alpha

1

15

High-throughput

0.536

High

862631

FOSB
Protein FosB

1

15

High-throughput

0.536

High

1054190

BECN1
Beclin-1

1

1

High-throughput

0.536

High

1071564

L2GL1
Lethal(2) giant larvae protein homolog 1

1

3

High-throughput

0.536

High

1301579

UBXN6
UBX domain-containing protein 6

1

1

High-throughput

0.536

High

1301584

HSPB8
Heat shock protein beta-8

1

7

High-throughput

0.536

High

1049436

MORC3
MORC family CW-type zinc finger protein 3

1

0

High-throughput

0.513

High

1301582

SLAI2
SLAIN motif-containing protein 2

1

0

High-throughput

0.513

High

574062

LOX12
Polyunsaturated fatty acid lipoxygenase ALOX12

1

4

Small-scale

0.508

High

1024078

ACACA
Acetyl-CoA carboxylase 1

1

11

Small-scale

0.501

High

1232689

FBXW8
F-box/WD repeat-containing protein 8

1

10

Small-scale

0.501

High

885351

INHBE
Inhibin beta E chain

1

1

High-throughput

0.489

High

993900

PCDH1
Protocadherin-1

1

4

High-throughput

0.489

High

1301580

KLC2
Kinesin light chain 2

1

2

Small-scale

0.481

High

1301581

MLXPL
Carbohydrate-responsive element-binding protein

1

3

Small-scale

0.479

High

831923

CEBPD
CCAAT/enhancer-binding protein delta

1

17

Small-scale

0.408

High

1077833

CEBPE
CCAAT/enhancer-binding protein epsilon

1

14

Small-scale

0.408

High

1245837

RASF8
Ras association domain-containing protein 8

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024