HitPredict

Interactor 1: ROA1 (P09651)
Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) (Helix-destabilizing protein) (Single-strand RNA-binding protein) (hnRNP core protein A1) [Cleaved into: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed]
Gene: HNRNPA1

Interactor 2: DSRAD (P55265)
Double-stranded RNA-specific adenosine deaminase (DRADA) (EC 3.5.4.37) (136 kDa double-stranded RNA-binding protein) (p136) (Interferon-inducible protein 4) (IFI-4) (K88DSRBP)
Gene: ADAR

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	26496610, 34079125, 22446626
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm and 2 others more... GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 372 Hs			1 1226
+	Hs
		161997 HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41		DSRAD_HUMAN (1-1226): 0: 1785: 100.00
+	Hs
		453558 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		STRBP_HUMAN (492-664): 1.81e-28: 124: 20.83
+	Hs
		453317 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		ILF3_HUMAN (504-660): 2.26e-26: 119: 19.77
+	Hs
		201705 MSI1H_HUMAN (2-340): 5.33e-59: 196: 27.87		STRBP_HUMAN (492-664): 1.81e-28: 124: 20.83
+	Hs
		322100 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		STAU1_HUMAN (567-891): 2.2e-25: 114: 16.95
+	Hs
		162030 HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41		ILF3_HUMAN (504-660): 2.26e-26: 119: 19.77
+	Hs
		609832 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		ILF3_HUMAN (504-660): 2.26e-26: 119: 19.77
+	Hs
		852033 ROA3_HUMAN (7-202): 5.98e-55: 186: 85.71		ILF3_HUMAN (504-660): 2.26e-26: 119: 19.77
+	Hs
		161925 HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41		STAU1_HUMAN (567-891): 2.2e-25: 114: 16.95
+	Hs
		322185 ROA2_HUMAN (1-339): 4.42e-56: 188: 59.00		STAU1_HUMAN (567-891): 2.2e-25: 114: 16.95
+	Hs
		322361 ROA3_HUMAN (7-202): 5.98e-55: 186: 85.71		STAU1_HUMAN (567-891): 2.2e-25: 114: 16.95
+	Hs
		453278 ROA1_HUMAN (1-372): 3.69e-61: 202: 100.00		RED1_HUMAN (678-800): 7.2e-11: 68.7: 21.05
+	Hs
		944810 RA1L2_HUMAN (1-302): 4.03e-58: 193: 83.44		RED1_HUMAN (678-800): 7.2e-11: 68.7: 21.05
+	Hs
		162010 HNRDL_HUMAN (2-283): 5.5e-56: 190: 32.41		RED1_HUMAN (678-800): 7.2e-11: 68.7: 21.05
+	Hs
		269714 ELAV2_HUMAN (1-186): 1.4e-22: 99.5: 14.98		PRKRA_HUMAN (611-893): 2.12e-42: 159: 21.89
+	Hs
		1019908 ROAA_HUMAN (6-184): 1.25e-35: 134: 39.44		ILF3_HUMAN (504-660): 2.26e-26: 119: 19.77
+	Hs
		323049 ROAA_HUMAN (6-184): 1.25e-35: 134: 39.44		STAU1_HUMAN (567-891): 2.2e-25: 114: 16.95
+	Hs
		1020315 ELAV2_HUMAN (1-186): 1.4e-22: 99.5: 14.98		STRBP_HUMAN (492-664): 1.81e-28: 124: 20.83
+	Hs
		1019708 ELAV2_HUMAN (1-186): 1.4e-22: 99.5: 14.98		ILF3_HUMAN (504-660): 2.26e-26: 119: 19.77
+	Hs
		944907 ROAA_HUMAN (6-184): 1.25e-35: 134: 39.44		RED1_HUMAN (678-800): 7.2e-11: 68.7: 21.05