Interactor 1: IFIT1 (P09914)
Interferon-induced protein with tetratricopeptide repeats 1 (IFIT-1) (Interferon-induced 56 kDa protein) (IFI-56K) (P56)
Gene: IFIT1

Interactor 2: IFIT5 (Q13325)
Interferon-induced protein with tetratricopeptide repeats 5 (IFIT-5) (Interferon-induced 58 kDa protein) (Retinoic acid- and interferon-inducible 58 kDa protein) (P58)
Gene: IFIT5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.52 1.00 0.724

The method score is based on:

Property Details
Experiments 21642987
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains TPR_10~TPR_12, TPR_12~TPR_12, TPR_12~TPR_8, TPR_19~TPR_2, TPR_2~TPR_2, TPR_2~TPR_8, TPR_8~TPR_8
Common GO terms GO:0003723 - RNA binding
GO:0005829 - cytosol
GO:0045071 - negative regulation of viral genome replication
GO:0051607 - defense response to virus
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 478
Hs

1 482
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Last updated: 15 Jul 2024