HitPredict

Interactor 1: DLG4 (P78352)
Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90)
Gene: DLG4

Interactor 2: NLGN1 (Q8N2Q7)
Neuroligin-1
Gene: NLGN1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.72 0.60 0.658

The method score is based on:

Property Details
Experiments 9278515, 30864948, 11937501
Identification Methods two hybrid, pull down, protein complementation assay, fluorescence polarization spectroscopy
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005886 - plasma membrane
GO:0007268 - chemical synaptic transmission
GO:0007399 - nervous system development
GO:0014069 - postsynaptic density
GO:0030165 - PDZ domain binding
and 13 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 724
Hs

1 863
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024