Interactor 1: RIR2 (P09938)
Ribonucleoside-diphosphate reductase small chain 1 (EC 1.17.4.1) (Ribonucleotide reductase R2 subunit 1) (Ribonucleotide reductase small subunit 1)
Gene: RNR2

Interactor 2: RIR2 (P09938)
Ribonucleoside-diphosphate reductase small chain 1 (EC 1.17.4.1) (Ribonucleotide reductase R2 subunit 1) (Ribonucleotide reductase small subunit 1)
Gene: RNR2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.77 1.00 0.879

The method score is based on:

Property Details
Experiments 9774971, 15196016, 11526232, 10716984
Identification Methods two hybrid, x-ray crystallography, pull down, cosedimentation through density gradient
Interaction Type direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Ribonuc_red_sm~Ribonuc_red_sm
Common GO terms GO:0004748 - ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005971 - ribonucleoside-diphosphate reductase complex
GO:0008198 - ferrous iron binding
and 4 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 399
Sc

1 399
+ Hs
+ Hs
+ Sc
+ Hs
+ Vv
+ Ce
+ Sc
+ Hh
+ Hh
+ Hh
+ Ec
+ Ha
+ Ec
+ Mp
+ Mt

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024