HitPredict

Interactor 1: SWI6 (P09959)
Regulatory protein SWI6 (Cell-cycle box factor subunit SWI6) (MBF subunit P90) (Trans-acting activator of HO endonuclease gene)
Gene: SWI6

Interactor 2: CDC14 (Q00684)
Tyrosine-protein phosphatase CDC14 (EC 3.1.3.48)
Gene: CDC14

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

Property	Details
Experiments	14993267, 28758351, 21179020
Identification Methods	enzymatic study, x-ray crystallography, tandem affinity purification
Interaction Type	direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 803 Sc			1 551
+	Sc
		763222 MBP1_YEAST (259-794): 3.11e-93: 312: 19.56		CDC14_YEAST (1-551): 0: 564: 100.00
+	Sc
		628886 SWI4_YEAST (238-767): 5.3e-72: 257: 18.50		CDC14_YEAST (1-551): 0: 564: 100.00
+	Sp
		783445 RES2_SCHPO (160-784): 3.43e-64: 229: 19.49		FLP1_SCHPO (3-548): 4.89e-156: 458: 40.00
+	Sp
		706682 RES1_SCHPO (306-749): 1.65e-56: 207: 20.05		FLP1_SCHPO (3-548): 4.89e-156: 458: 40.00
+	Sp
		351028 CDC10_SCHPO (237-799): 3.76e-52: 196: 26.61		FLP1_SCHPO (3-548): 4.89e-156: 458: 40.00
+	Hs
		166860 ANR28_HUMAN (58-560): 7.66e-45: 176: 14.13		CC14B_HUMAN (4-464): 8.94e-155: 453: 29.55
+	Hs
		239362 ANR44_HUMAN (20-502): 6.35e-34: 142: 13.93		CC14B_HUMAN (4-464): 8.94e-155: 453: 29.55
+	Hs
		239422 ANR50_HUMAN (330-792): 4.76e-32: 136: 11.09		CC14B_HUMAN (4-464): 8.94e-155: 453: 29.55
+	Hs
		239365 ANR52_HUMAN (154-430): 1.19e-19: 96.7: 11.70		CC14B_HUMAN (4-464): 8.94e-155: 453: 29.55
+	Hs
		890841 TNKS2_HUMAN (189-690): 1.82e-59: 221: 12.50		PTEN_HUMAN (152-540): 3.27e-74: 243: 14.53
+	Hs
		310043 TNKS1_HUMAN (154-801): 1.8e-57: 215: 11.49		PTEN_HUMAN (152-540): 3.27e-74: 243: 14.53
+	Hs
		1219833 ANKH1_HUMAN (96-491): 1.16e-34: 145: 11.31		DUS16_HUMAN (192-546): 2.49e-65: 226: 15.39
+	Hs
		167013 ANR28_HUMAN (58-560): 7.66e-45: 176: 14.13		DUS15_HUMAN (202-497): 6.22e-47: 167: 13.00
+	Hs
		260624 RAI14_HUMAN (268-799): 3.89e-51: 195: 12.48		TP4A3_HUMAN (188-362): 3.27e-40: 145: 23.20
+	Hs
		56494 ANR28_HUMAN (58-560): 7.66e-45: 176: 14.13		PTPC1_HUMAN (162-371): 6.16e-37: 147: 18.06
+	Hs
		161735 KDIS_HUMAN (445-803): 2.58e-33: 141: 9.76		GAK_HUMAN (115-347): 3.7e-43: 167: 14.35
+	Hs
		474837 POTEI_HUMAN (242-740): 1.27e-25: 115: 14.54		SSH1_HUMAN (212-450): 7.58e-41: 160: 10.93
+	Hs
		60258 POTEF_HUMAN (383-796): 2.19e-22: 105: 13.78		TP4A3_HUMAN (188-362): 3.27e-40: 145: 23.20
+	Hs
		474845 POTEI_HUMAN (242-740): 1.27e-25: 115: 14.54		DUS23_HUMAN (173-334): 4.6e-36: 133: 20.99
+	Hs
		1021808 ANR52_HUMAN (154-430): 1.19e-19: 96.7: 11.70		TP4A2_HUMAN (188-355): 2.35e-39: 143: 27.01