Protein: PPM1H
Protein phosphatase 1H (EC 3.1.3.16)

Gene: PPM1H
Organism: Homo sapiens
Interactions: 121
UniProt ID: Q9ULR3

Gene Ontology (top 5):
GO:0004721 - phosphoprotein phosphatase activity
GO:0004741 - [pyruvate dehydrogenase (acetyl-transferring)]-phosphatase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1126990

PPM1J
Protein phosphatase 1J

3

5

Small-scale

0.855

High

1356972

PPM1H
Protein phosphatase 1H

2

5

High-throughput

0.783

High

905248

1433G
14-3-3 protein gamma

4

8

High-throughput

0.697

High

982613

1433F
14-3-3 protein eta

4

8

High-throughput

0.697

High

683807

1433B
14-3-3 protein beta/alpha

3

8

High-throughput

0.675

High

682067

AKT1
RAC-alpha serine/threonine-protein kinase

1

3

Small-scale

0.647

High

647374

1433T
14-3-3 protein theta

2

8

High-throughput

0.628

High

910147

1433E
14-3-3 protein epsilon

2

1

High-throughput

0.628

High

927649

1433Z
14-3-3 protein zeta/delta

2

8

High-throughput

0.628

High

230931

MAST3
Microtubule-associated serine/threonine-protein kinase 3

1

3

High-throughput

0.618

High

960425

CDK16
Cyclin-dependent kinase 16

1

5

High-throughput

0.618

High

1057212

MELK
Maternal embryonic leucine zipper kinase

1

17

High-throughput

0.618

High

1130720

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

2

Small-scale

0.575

High

166630

DCLK1
Serine/threonine-protein kinase DCLK1

1

13

High-throughput

0.553

High

867663

BLM
RecQ-like DNA helicase BLM

1

1

High-throughput

0.536

High

1298552

ZN641
Zinc finger protein 641

1

0

High-throughput

0.513

High

1350058

ZN492
Zinc finger protein 492

1

0

High-throughput

0.513

High

202784

TPD54
Tumor protein D54

1

1

High-throughput

0.479

High

253431

SRGP2
SLIT-ROBO Rho GTPase-activating protein 2

1

1

High-throughput

0.479

High

598543

NF1
Neurofibromin

1

1

High-throughput

0.479

High

673535

MPIP2
M-phase inducer phosphatase 2

1

1

High-throughput

0.479

High

673640

MPIP3
M-phase inducer phosphatase 3

1

1

High-throughput

0.479

High

878058

TPD52
Tumor protein D52

1

1

High-throughput

0.479

High

880852

HDAC4
Histone deacetylase 4

1

3

High-throughput

0.479

High

1020237

PTN13
Tyrosine-protein phosphatase non-receptor type 13

1

2

High-throughput

0.479

High

1022472

TIAM1
Rho guanine nucleotide exchange factor TIAM1

1

1

High-throughput

0.479

High

1076941

PTN14
Tyrosine-protein phosphatase non-receptor type 14

1

2

High-throughput

0.479

High

1136492

M3K21
Mitogen-activated protein kinase kinase kinase 21

1

5

High-throughput

0.479

High

1136561

SPD2A
SH3 and PX domain-containing protein 2A

1

1

High-throughput

0.479

High

1153446

PKHA7
Pleckstrin homology domain-containing family A member 7

1

2

High-throughput

0.479

High

1162712

LARP1
La-related protein 1

1

1

High-throughput

0.479

High

1172242

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.479

High

1185274

RFIP2
Rab11 family-interacting protein 2

1

3

High-throughput

0.479

High

1189740

MYCPP
C-myc promoter-binding protein

1

3

High-throughput

0.479

High

1203951

RGPS2
Ras-specific guanine nucleotide-releasing factor RalGPS2

1

1

High-throughput

0.479

High

1218000

KSR1
Kinase suppressor of Ras 1

1

3

High-throughput

0.479

High

1230067

RPTOR
Regulatory-associated protein of mTOR

1

1

High-throughput

0.479

High

1253346

F110B
Protein FAM110B

1

1

High-throughput

0.479

High

1260202

HDAC7
Histone deacetylase 7

1

3

High-throughput

0.479

High

1263477

SRS12
Serine/arginine-rich splicing factor 12

1

1

High-throughput

0.479

High

1267570

TSC1
Hamartin

1

2

High-throughput

0.479

High

1270522

HDAC2
Histone deacetylase 2

1

1

High-throughput

0.479

High

1300693

MAGI1
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1

1

1

High-throughput

0.479

High

1301724

TESK2
Dual specificity testis-specific protein kinase 2

1

2

High-throughput

0.479

High

1309184

F110A
Protein FAM110A

1

1

High-throughput

0.479

High

1334859

PKHA5
Pleckstrin homology domain-containing family A member 5

1

3

High-throughput

0.479

High

1343633

KI13B
Kinesin-like protein KIF13B

1

1

High-throughput

0.479

High

1345064

INP5E
Phosphatidylinositol polyphosphate 5-phosphatase type IV

1

1

High-throughput

0.479

High

1347912

MIOS
GATOR2 complex protein MIOS

1

1

High-throughput

0.479

High

1354836

ZRAN1
Ubiquitin thioesterase ZRANB1

1

3

High-throughput

0.479

High

1356316

UBP21
Ubiquitin carboxyl-terminal hydrolase 21

1

1

High-throughput

0.479

High

1356974

AGAP1
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1

1

1

High-throughput

0.479

High

1356975

GAB2
GRB2-associated-binding protein 2

1

3

High-throughput

0.479

High

152181

STX16
Syntaxin-16

1

0

High-throughput

0.458

High

170977

PGRC2
Membrane-associated progesterone receptor component 2

1

0

High-throughput

0.458

High

196529

SI1L1
Signal-induced proliferation-associated 1-like protein 1

1

0

High-throughput

0.458

High

237343

IF4E2
Eukaryotic translation initiation factor 4E type 2

1

0

High-throughput

0.458

High

403998

ITB1
Integrin beta-1

1

0

High-throughput

0.458

High

946764

TMF1
TATA element modulatory factor

1

0

High-throughput

0.458

High

993088

RHG01
Rho GTPase-activating protein 1

1

0

High-throughput

0.458

High

1034642

GOGA4
Golgin subfamily A member 4

1

0

High-throughput

0.458

High

1060648

ZN638
Zinc finger protein 638

1

0

High-throughput

0.458

High

1243701

NAV1
Neuron navigator 1

1

0

High-throughput

0.458

High

1308734

SIN1
Target of rapamycin complex 2 subunit MAPKAP1

1

0

High-throughput

0.458

High

1309750

LPIN3
Phosphatidate phosphatase LPIN3

1

0

High-throughput

0.458

High

1318116

WDR11
WD repeat-containing protein 11

1

0

High-throughput

0.458

High

1348457

FA53C
Protein FAM53C

1

0

High-throughput

0.458

High

1355872

LCAP
Leucyl-cystinyl aminopeptidase

1

0

High-throughput

0.458

High

1356891

ZBT21
Zinc finger and BTB domain-containing protein 21

1

0

High-throughput

0.458

High

1356976

CBY1
Protein chibby homolog 1

1

0

High-throughput

0.458

High

136083

ACACB
Acetyl-CoA carboxylase 2

1

1

Small-scale

0.445

High

160963

RAB7L
Ras-related protein Rab-7L1

1

7

Small-scale

0.445

High

592574

RAB5A
Ras-related protein Rab-5A

1

5

Small-scale

0.445

High

845348

RAB7A
Ras-related protein Rab-7a

1

6

Small-scale

0.445

High

894824

RAB8A
Ras-related protein Rab-8A

1

5

Small-scale

0.445

High

1024113

ACACA
Acetyl-CoA carboxylase 1

1

1

Small-scale

0.445

High

216989

KIF1C
Kinesin-like protein KIF1C

1

1

High-throughput

0.437

High

264439

GGYF1
GRB10-interacting GYF protein 1

1

1

High-throughput

0.437

High

926266

VAMP2
Vesicle-associated membrane protein 2

1

1

High-throughput

0.437

High

1079468

VAMP3
Vesicle-associated membrane protein 3

1

1

High-throughput

0.437

High

1139652

DEN4C
DENN domain-containing protein 4C

1

3

High-throughput

0.437

High

1149012

AN34A
Ankyrin repeat domain-containing protein 34A

1

1

High-throughput

0.437

High

1168010

GGYF2
GRB10-interacting GYF protein 2

1

2

High-throughput

0.437

High

1173163

SYDE1
Rho GTPase-activating protein SYDE1

1

3

High-throughput

0.437

High

1256268

DEN1A
DENN domain-containing protein 1A

1

3

High-throughput

0.437

High

1256287

SH3R3
E3 ubiquitin-protein ligase SH3RF3

1

4

High-throughput

0.437

High

1260799

DEP1B
DEP domain-containing protein 1B

1

1

High-throughput

0.437

High

1355994

NGAP
Ras GTPase-activating protein nGAP

1

1

High-throughput

0.437

High

1356977

STA13
StAR-related lipid transfer protein 13

1

2

High-throughput

0.437

High

918129

H4
Histone H4

1

0

Small-scale

0.426

High

1307131

H2B1M
Histone H2B type 1-M

1

0

Small-scale

0.426

High

1330279

GCP60
Golgi resident protein GCP60

1

0

Small-scale

0.426

High

844795

RAB5C
Ras-related protein Rab-5C

1

6

Small-scale

0.407

High

845891

RAB13
Ras-related protein Rab-13

1

5

Small-scale

0.407

High

895391

RAB5B
Ras-related protein Rab-5B

1

6

Small-scale

0.407

High

895565

RAB10
Ras-related protein Rab-10

1

5

Small-scale

0.407

High

918966

RAB1A
Ras-related protein Rab-1A

1

3

Small-scale

0.407

High

1070453

RAB35
Ras-related protein Rab-35

1

6

Small-scale

0.407

High

1273013

RAB8B
Ras-related protein Rab-8B

1

5

Small-scale

0.407

High

1328157

RAB1B
Ras-related protein Rab-1B

1

4

Small-scale

0.407

High

168464

SCAM1
Secretory carrier-associated membrane protein 1

1

0

High-throughput

0.249

Low

280315

CBPD
Carboxypeptidase D

1

0

High-throughput

0.249

Low

316289

NADK
NAD kinase

1

0

High-throughput

0.249

Low

514931

MPRI
Cation-independent mannose-6-phosphate receptor

1

0

High-throughput

0.249

Low

825596

LMAN1
Protein ERGIC-53

1

0

High-throughput

0.249

Low

997236

CAMP2
Calmodulin-regulated spectrin-associated protein 2

1

0

High-throughput

0.249

Low

1109701

TBC25
TBC1 domain family member 25

1

0

High-throughput

0.249

Low

1145648

F91A1
Protein FAM91A1

1

0

High-throughput

0.249

Low

1197853

PHLB2
Pleckstrin homology-like domain family B member 2

1

0

High-throughput

0.249

Low

1311610

RTKN
Rhotekin

1

0

High-throughput

0.249

Low

1318037

OSBL6
Oxysterol-binding protein-related protein 6

1

0

High-throughput

0.249

Low

1329473

S6A15
Sodium-dependent neutral amino acid transporter B(0)AT2

1

0

High-throughput

0.249

Low

1335968

TANC2
Protein TANC2

1

0

High-throughput

0.249

Low

1350023

LRFN1
Leucine-rich repeat and fibronectin type III domain-containing protein 1

1

0

High-throughput

0.249

Low

1350452

CING
Cingulin

1

0

High-throughput

0.249

Low

1355277

LIMA1
LIM domain and actin-binding protein 1

1

0

High-throughput

0.249

Low

1356973

S12A4
Solute carrier family 12 member 4

1

0

High-throughput

0.249

Low

1356978

KCTD3
BTB/POZ domain-containing protein KCTD3

1

0

High-throughput

0.249

Low

176879

EIF3D
Eukaryotic translation initiation factor 3 subunit D

1

0

Small-scale

0.232

Low

1298092

CEP63
Centrosomal protein of 63 kDa

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024