HitPredict

Interactor 1: NTCA (P0A4U6)
Global nitrogen regulator (DNA-binding protein VF1) (Nitrogen-responsive regulatory protein)
Gene: NTCA

Interactor 2: NTCA (P0A4U6)
Global nitrogen regulator (DNA-binding protein VF1) (Nitrogen-responsive regulatory protein)
Gene: NTCA

Species: Nostoc sp. PCC 7120 = FACHB-418

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	20616047
Identification Methods	x-ray crystallography
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	cNMP_binding~cNMP_binding, HTH_Crp_2~cNMP_binding, HTH_Crp_2~HTH_Crp_2
Common GO terms	GO:0003677 - DNA binding GO:0003700 - DNA-binding transcription factor activity GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 223 Ns			1 223
+	Se
		664396 NTCA_SYNE7 (2-223): 2.23e-60: 190: 77.03		NTCA_SYNE7 (2-223): 2.23e-60: 190: 77.03
+	Ec
		467295 CRP_ECOLI (13-216): 3.85e-52: 169: 24.88		CRP_ECOLI (13-216): 3.85e-52: 169: 24.88
+	Pa
		877180 VFR_PSEAE (14-216): 2.25e-49: 162: 21.85		VFR_PSEAE (14-216): 2.25e-49: 162: 21.85
+	At
		1107042 KAT1_ARATH (2-206): 7.88e-39: 143: 15.05		KAT1_ARATH (2-206): 7.88e-39: 143: 15.05
+	Ce
		106779 G5EEE2_CAEEL (3-212): 4.11e-38: 142: 14.62		CNG_CAEEL (3-206): 6.49e-37: 138: 16.51
+	Ce
		977019 CNG_CAEEL (3-206): 6.49e-37: 138: 16.51		CNG_CAEEL (3-206): 6.49e-37: 138: 16.51
+	Hs
		1377721 HCN4_HUMAN (2-168): 1.71e-36: 137: 18.13		HCN4_HUMAN (2-168): 1.71e-36: 137: 18.13
+	At
		1105413 KAT1_ARATH (2-206): 7.88e-39: 143: 15.05		AKT1_ARATH (2-156): 4.08e-34: 130: 12.82
+	Hs
		1356781 HCN4_HUMAN (2-168): 1.71e-36: 137: 18.13		HCN2_HUMAN (2-177): 3.89e-36: 136: 18.33
+	Hs
		1356780 HCN2_HUMAN (2-177): 3.89e-36: 136: 18.33		HCN2_HUMAN (2-177): 3.89e-36: 136: 18.33
+	Mm
		71335 B2RY58_MOUSE (2-168): 2.95e-36: 136: 18.13		HCN2_MOUSE (2-177): 5.09e-36: 135: 18.33
+	Mm
		292102 HCN2_MOUSE (2-177): 5.09e-36: 135: 18.33		HCN2_MOUSE (2-177): 5.09e-36: 135: 18.33
+	Hs
		1349966 HCN4_HUMAN (2-168): 1.71e-36: 137: 18.13		HCN3_HUMAN (2-146): 7.97e-34: 129: 17.81
+	Hs
		240287 HCN4_HUMAN (2-168): 1.71e-36: 137: 18.13		HCN1_HUMAN (2-143): 7.94e-34: 129: 19.58
+	Hs
		240252 HCN2_HUMAN (2-177): 3.89e-36: 136: 18.33		HCN1_HUMAN (2-143): 7.94e-34: 129: 19.58
+	Mm
		71336 B2RY58_MOUSE (2-168): 2.95e-36: 136: 18.13		HCN1_MOUSE (2-143): 7.98e-34: 129: 19.58
+	Mm
		292103 HCN2_MOUSE (2-177): 5.09e-36: 135: 18.33		HCN1_MOUSE (2-143): 7.98e-34: 129: 19.58