HitPredict

Interactor 1: EFTS (P0A6P1)
Elongation factor Ts (EF-Ts) (Bacteriophage Q beta RNA-directed RNA polymerase subunit IV)
Gene: tsf

Interactor 2: EFTU2 (P0CE48)
Elongation factor Tu 2 (EF-Tu 2) (Bacteriophage Q beta RNA-directed RNA polymerase subunit III) (P-43)
Gene: tufB

Species: Escherichia coli K-12

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	1.00	0.827

Property	Details
Experiments	16606699, 8596629, 15690043
Identification Methods	affinity chromatography technology, x-ray crystallography, tandem affinity purification
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	EF_TS~GTP_EFTU, EF_TS~GTP_EFTU_D3
Common GO terms	GO:0003746 - translation elongation factor activity GO:0005829 - cytosol GO:0006414 - translational elongation GO:0032045 - guanyl-nucleotide exchange factor complex
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 283 Ec			1 394
+	Ec
		458600 EFTS_ECOLI (1-283): 5.78e-109: 318: 100.00		EFTU1_ECOLI (1-393): 1.21e-158: 453: 100.00
+	Mp
		618374 EFTS_MYCPN (7-282): 1.4e-88: 267: 38.91		EFTU_MYCPN (1-393): 2.04e-157: 450: 70.23
+	Bs
		702822 EFTS_BACSU (3-282): 1.86e-90: 272: 48.97		EFTU_BACSU (1-392): 3.09e-154: 442: 76.65
+	Bt
		799171 EFTS_BOVIN (6-271): 3.65e-93: 280: 24.32		EFTU_BOVIN (2-391): 2.73e-150: 434: 56.12
+	Hs
		799178 EFTS_HUMAN (2-259): 2.89e-89: 270: 24.65		EFTU_HUMAN (2-394): 2.29e-148: 429: 55.44
+	Dm
		1179843 EFTS_DROME (4-268): 8.27e-86: 260: 27.65		Q7K3V6_DROME (8-393): 1.84e-133: 391: 51.03
+	Ce
		105315 EFTS_CAEEL (3-262): 4.85e-68: 215: 23.76		G5ECM6_CAEEL (3-393): 4.29e-132: 389: 51.13
+	Ce
		106058 EFTS_CAEEL (3-262): 4.85e-68: 215: 23.76		G5EDF5_CAEEL (10-392): 2.54e-111: 334: 45.46