HitPredict

Interactor 1: HS90A (P07900)
Heat shock protein HSP 90-alpha (EC 3.6.4.10) (Heat shock 86 kDa) (HSP 86) (HSP86) (Heat shock protein family C member 1) (Lipopolysaccharide-associated protein 2) (LAP-2) (LPS-associated protein 2) (Renal carcinoma antigen NY-REN-38)
Gene: HSP90AA1

Interactor 2: KCNS3 (Q9BQ31)
Delayed-rectifier potassium channel regulatory subunit KCNS3 (Delayed-rectifier K(+) channel alpha subunit 3) (Delayed-rectifier potassium channel subunit Kv9.3) (Kv9.3) (Potassium voltage-gated channel subfamily S member 3)
Gene: KCNS3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22939624
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 732 Hs			1 491
+	Hs
		468738 HS90B_HUMAN (19-732): 0: 1057: 86.13		KCNS3_HUMAN (1-491): 1.28e-150: 440: 100.00
+	Hs
		462022 HS90A_HUMAN (1-732): 0: 1085: 100.00		KCND3_HUMAN (7-486): 5.93e-123: 375: 28.60
+	Hs
		461147 HS90A_HUMAN (1-732): 0: 1085: 100.00		KCNA3_HUMAN (7-490): 4.71e-115: 352: 27.84
+	Hs
		461150 HS90A_HUMAN (1-732): 0: 1085: 100.00		KCNA5_HUMAN (8-487): 2.46e-111: 344: 26.43
+	Hs
		468068 HS90B_HUMAN (19-732): 0: 1057: 86.13		KCNA3_HUMAN (7-490): 4.71e-115: 352: 27.84
+	Hs
		462018 HS90A_HUMAN (1-732): 0: 1085: 100.00		KCNG1_HUMAN (8-429): 1.57e-104: 323: 36.18
+	Hs
		468072 HS90B_HUMAN (19-732): 0: 1057: 86.13		KCNA5_HUMAN (8-487): 2.46e-111: 344: 26.43
+	Hs
		468891 HS90B_HUMAN (19-732): 0: 1057: 86.13		KCNG1_HUMAN (8-429): 1.57e-104: 323: 36.18
+	Hs
		573326 ENPL_HUMAN (14-701): 0: 896: 46.78		KCNA3_HUMAN (7-490): 4.71e-115: 352: 27.84
+	Mm
		465802 ENPL_MOUSE (14-732): 0: 898: 45.07		KCNA3_MOUSE (7-490): 8.08e-113: 345: 27.65