Protein: KCNA5
Potassium voltage-gated channel subfamily A member 5 (HPCN1) (Voltage-gated potassium channel HK2) (Voltage-gated potassium channel subunit Kv1.5)

Gene: KCNA5
Organism: Homo sapiens
Interactions: 60
UniProt ID: P22460

Gene Ontology (top 5):
GO:0001508 - action potential
GO:0001666 - response to hypoxia
GO:0005102 - signaling receptor binding
GO:0005249 - voltage-gated potassium channel activity
GO:0005251 - delayed rectifier potassium channel activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

642619

KCNA3
Potassium voltage-gated channel subfamily A member 3

4

15

Small-scale

0.896

High

648818

KCAB2
Voltage-gated potassium channel subunit beta-2

4

13

Small-scale

0.892

High

648807

ACTN2
Alpha-actinin-2

3

4

Small-scale

0.884

High

595032

KCNA2
Potassium voltage-gated channel subfamily A member 2

2

14

Small-scale

0.754

High

648823

KCAB1
Voltage-gated potassium channel subunit beta-1

2

13

Small-scale

0.737

High

648813

DLG4
Disks large homolog 4

3

20

Small-scale

0.669

High

648814

CAV1
Caveolin-1

3

2

Small-scale

0.640

High

648817

DLG1
Disks large homolog 1

3

20

Small-scale

0.640

High

648806

AT2B4
Plasma membrane calcium-transporting ATPase 4

2

7

High-throughput

0.628

High

648824

ZNT6
Zinc transporter 6

2

3

High-throughput

0.628

High

648826

ADCK2
Uncharacterized aarF domain-containing protein kinase 2

2

1

High-throughput

0.628

High

648827

ANKL2
Ankyrin repeat and LEM domain-containing protein 2

2

1

High-throughput

0.628

High

648828

GHDC
GH3 domain-containing protein

2

1

High-throughput

0.628

High

648829

GOLM1
Golgi membrane protein 1

2

4

High-throughput

0.628

High

648832

AT2A3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

2

6

High-throughput

0.628

High

648838

CA043
Protein C1orf43

2

3

High-throughput

0.628

High

648843

NB5R1
NADH-cytochrome b5 reductase 1

2

2

High-throughput

0.628

High

648845

VANG2
Vang-like protein 2

2

4

High-throughput

0.628

High

648848

S27A6
Long-chain fatty acid transport protein 6

2

3

High-throughput

0.628

High

648850

RHBD3
Rhomboid domain-containing protein 3

2

6

High-throughput

0.628

High

648762

KCNA4
Potassium voltage-gated channel subfamily A member 4

1

14

Small-scale

0.618

High

648844

KCND3
A-type voltage-gated potassium channel KCND3

1

14

Small-scale

0.618

High

184267

NPHP1
Nephrocystin-1

2

0

High-throughput

0.602

High

557094

SRC
Proto-oncogene tyrosine-protein kinase Src

2

9

Small-scale

0.584

High

648821

FHL1
Four and a half LIM domains protein 1

2

1

Small-scale

0.584

High

648825

TM107
Transmembrane protein 107

2

0

High-throughput

0.580

High

606061

KCNA6
Potassium voltage-gated channel subfamily A member 6

1

16

High-throughput

0.575

High

49435

TM223
Transmembrane protein 223

2

1

High-throughput

0.574

High

648833

SARAF
Store-operated calcium entry-associated regulatory factor

2

1

High-throughput

0.574

High

648840

DJC18
DnaJ homolog subfamily C member 18

2

8

High-throughput

0.574

High

648842

ABCBA
ATP-binding cassette sub-family B member 10, mitochondrial

2

4

High-throughput

0.574

High

648847

DOLK
Dolichol kinase

2

5

High-throughput

0.574

High

648849

TMX2
Thioredoxin-related transmembrane protein 2

2

2

High-throughput

0.574

High

648812

UBC9
SUMO-conjugating enzyme UBC9

1

1

Small-scale

0.561

High

648816

ACK1
Activated CDC42 kinase 1

1

15

Small-scale

0.536

High

161125

ABCD4
Lysosomal cobalamin transporter ABCD4

1

8

High-throughput

0.536

High

243785

ADCY3
Adenylate cyclase type 3

1

1

High-throughput

0.536

High

648830

LEMD2
LEM domain-containing protein 2

1

3

High-throughput

0.536

High

648841

CD320
CD320 antigen

1

6

High-throughput

0.536

High

648819

SNTA1
Alpha-1-syntrophin

1

20

Small-scale

0.527

High

648835

ERBIN
Erbin

1

10

Small-scale

0.527

High

648837

YIPF4
Protein YIPF4

1

0

High-throughput

0.513

High

648831

RHBL4
Rhomboid-related protein 4

1

4

High-throughput

0.489

High

156596

DC1I1
Cytoplasmic dynein 1 intermediate chain 1

1

1

Small-scale

0.479

High

436610

KPCB
Protein kinase C beta type

1

5

Small-scale

0.479

High

440367

FYN
Tyrosine-protein kinase Fyn

1

9

Small-scale

0.479

High

461150

HS90A
Heat shock protein HSP 90-alpha

1

12

High-throughput

0.479

High

468072

HS90B
Heat shock protein HSP 90-beta

1

12

High-throughput

0.479

High

536502

HSP7C
Heat shock cognate 71 kDa protein

1

7

Small-scale

0.479

High

648810

SUMO1
Small ubiquitin-related modifier 1

1

5

Small-scale

0.479

High

648811

RACK1
Small ribosomal subunit protein RACK1

1

2

Small-scale

0.479

High

648815

KPCT
Protein kinase C theta type

1

5

Small-scale

0.479

High

648820

DCTN2
Dynactin subunit 2

1

1

Small-scale

0.479

High

648822

SCRIB
Protein scribble homolog

1

20

Small-scale

0.479

High

648834

SIR1
NAD-dependent protein deacetylase sirtuin-1

1

1

Small-scale

0.479

High

648846

CHIP
E3 ubiquitin-protein ligase CHIP

1

5

Small-scale

0.479

High

648808

SUMO3
Small ubiquitin-related modifier 3

1

5

Small-scale

0.437

High

648809

SUMO2
Small ubiquitin-related modifier 2

1

5

Small-scale

0.437

High

648839

5NT3A
Cytosolic 5'-nucleotidase 3A

2

0

High-throughput

0.328

High

648836

CQ080
Mitochondrial nucleoid-associated protein 1

2

0

High-throughput

0.324

High


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Last updated: 11Aug2025