HitPredict

Interactor 1: HS90A (P07900)
Heat shock protein HSP 90-alpha (EC 3.6.4.10) (Heat shock 86 kDa) (HSP 86) (HSP86) (Heat shock protein family C member 1) (Lipopolysaccharide-associated protein 2) (LAP-2) (LPS-associated protein 2) (Renal carcinoma antigen NY-REN-38)
Gene: HSP90AA1

Interactor 2: MLP3B (Q9GZQ8)
Microtubule-associated protein 1 light chain 3 beta (Autophagy-related protein LC3 B) (Autophagy-related ubiquitin-like modifier LC3 B) (MAP1 light chain 3-like protein 2) (Microtubule-associated proteins 1A/1B light chain 3B) (MAP1A/MAP1B LC3 B) (MAP1A/MAP1B light chain 3 B)
Gene: MAP1LC3B

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29149599
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion GO:0005829 - cytosol GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 732 Hs			1 125
+	Hs
		461932 HS90A_HUMAN (1-732): 0: 1085: 100.00		MLP3A_HUMAN (1-120): 8.25e-55: 168: 82.50
+	Hs
		461327 HS90A_HUMAN (1-732): 0: 1085: 100.00		GBRL2_HUMAN (7-120): 2.22e-53: 165: 39.47
+	Hs
		327741 HS90A_HUMAN (1-732): 0: 1085: 100.00		GBRAP_HUMAN (7-121): 6.43e-53: 163: 31.30
+	Hs
		461921 HS90A_HUMAN (1-732): 0: 1085: 100.00		GBRL1_HUMAN (7-120): 1.51e-51: 160: 32.46
+	Rn
		1013212 HS90A_RAT (1-732): 0: 1083: 97.95		GBRL1_RAT (7-120): 1.51e-51: 160: 32.46
+	Hs
		468778 HS90B_HUMAN (19-732): 0: 1057: 86.13		MLP3B_HUMAN (1-125): 8.31e-57: 173: 100.00
+	Hs
		468802 HS90B_HUMAN (19-732): 0: 1057: 86.13		MLP3A_HUMAN (1-120): 8.25e-55: 168: 82.50
+	Hs
		468230 HS90B_HUMAN (19-732): 0: 1057: 86.13		GBRL2_HUMAN (7-120): 2.22e-53: 165: 39.47
+	Rn
		756532 HS90B_RAT (19-732): 0: 1061: 86.98		GBRL1_RAT (7-120): 1.51e-51: 160: 32.46
+	Hs
		327743 HS90B_HUMAN (19-732): 0: 1057: 86.13		GBRAP_HUMAN (7-121): 6.43e-53: 163: 31.30
+	Hs
		468789 HS90B_HUMAN (19-732): 0: 1057: 86.13		GBRL1_HUMAN (7-120): 1.51e-51: 160: 32.46
+	Sc
		392618 HSP82_YEAST (16-732): 0: 907: 60.08		ATG8_YEAST (4-120): 5.71e-55: 168: 34.19
+	Hs
		573415 ENPL_HUMAN (14-701): 0: 896: 46.78		GBRL2_HUMAN (7-120): 2.22e-53: 165: 39.47
+	Hs
		327778 ENPL_HUMAN (14-701): 0: 896: 46.78		GBRAP_HUMAN (7-121): 6.43e-53: 163: 31.30
+	Hs
		573664 ENPL_HUMAN (14-701): 0: 896: 46.78		GBRL1_HUMAN (7-120): 1.51e-51: 160: 32.46
+	Hs
		952168 HS902_HUMAN (1-344): 0: 561: 96.22		GBRL2_HUMAN (7-120): 2.22e-53: 165: 39.47
+	Hs
		328010 HS902_HUMAN (1-344): 0: 561: 96.22		GBRAP_HUMAN (7-121): 6.43e-53: 163: 31.30
+	Hs
		1128330 HS902_HUMAN (1-344): 0: 561: 96.22		GBRL1_HUMAN (7-120): 1.51e-51: 160: 32.46