HitPredict

Interactor 1: RPOA (P0A7Z4)
DNA-directed RNA polymerase subunit alpha (RNAP subunit alpha) (EC 2.7.7.6) (RNA polymerase subunit alpha) (Transcriptase subunit alpha)
Gene: RPOA

Interactor 2: RPOC (P0A8T7)
DNA-directed RNA polymerase subunit beta' (RNAP subunit beta') (EC 2.7.7.6) (RNA polymerase subunit beta') (Transcriptase subunit beta')
Gene: RPOC

Species: Escherichia coli K-12

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 1.00 0.926

The method score is based on:

Property Details
Experiments 16606699, 19903881, 24402227, 15690043, 10764785
Identification Methods affinity chromatography technology, pull down, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains RNA_pol_A_CTD~RNA_pol_Rpb1_2, RNA_pol_L~RNA_pol_Rpb1_2, RNA_pol_L~RNA_pol_Rpb1_3, RNA_pol_L~RNA_pol_Rpb1_4, RNA_pol_L~RNA_pol_Rpb1_5
Common GO terms GO:0000345 - cytosolic DNA-directed RNA polymerase complex
GO:0003677 - DNA binding
GO:0003899 - DNA-directed 5'-3' RNA polymerase activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 14 others

more...
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 329
Ec

1 1407
+ Nv
+ Hp
+ Mp
+ Tt

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024