Protein: HNRC1
Heterogeneous nuclear ribonucleoprotein C-like 1 (hnRNP C-like-1) (hnRNP core protein C-like 1)

Gene: HNRC1, HNRNPCL1
Organism: Homo sapiens
Interactions: 173
UniProt ID: O60812

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0042802 - identical protein binding
GO:1990904 - ribonucleoprotein complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

256567

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

6

15

High-throughput

0.942

High

74406

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

4

15

High-throughput

0.894

High

256639

RALYL
RNA-binding Raly-like protein

3

16

High-throughput

0.843

High

256614

ELAV2
ELAV-like protein 2

2

19

High-throughput

0.811

High

256701

RALY
RNA-binding protein Raly

2

14

High-throughput

0.793

High

256554

HNRC1
Heterogeneous nuclear ribonucleoprotein C-like 1

2

15

High-throughput

0.783

High

256605

YBOX1
Y-box-binding protein 1

2

17

Small-scale

0.776

High

256589

FUS
RNA-binding protein FUS

2

20

High-throughput

0.737

High

256681

MYLK2
Myosin light chain kinase 2, skeletal/cardiac muscle

2

5

High-throughput

0.737

High

214261

MSI1H
RNA-binding protein Musashi homolog 1

1

20

High-throughput

0.691

High

224063

BUB1
Mitotic checkpoint serine/threonine-protein kinase BUB1

1

6

High-throughput

0.691

High

256560

SRS10
Serine/arginine-rich splicing factor 10

1

20

High-throughput

0.691

High

256570

RU2A
U2 small nuclear ribonucleoprotein A'

1

1

High-throughput

0.691

High

256578

E2AK2
Interferon-induced, double-stranded RNA-activated protein kinase

1

10

High-throughput

0.691

High

256580

KAPCG
cAMP-dependent protein kinase catalytic subunit gamma

1

1

High-throughput

0.691

High

256595

CLK2
Dual specificity protein kinase CLK2

1

20

High-throughput

0.691

High

256596

CLK3
Dual specificity protein kinase CLK3

1

20

High-throughput

0.691

High

256607

SRPK2
SRSF protein kinase 2

1

20

High-throughput

0.691

High

256608

PRR3
Proline-rich protein 3

1

5

High-throughput

0.691

High

256612

NCBP1
Nuclear cap-binding protein subunit 1

1

5

High-throughput

0.691

High

256615

PPIG
Peptidyl-prolyl cis-trans isomerase G

1

3

High-throughput

0.691

High

256617

TRA2A
Transformer-2 protein homolog alpha

1

20

High-throughput

0.691

High

256623

HNRPD
Heterogeneous nuclear ribonucleoprotein D0

1

20

High-throughput

0.691

High

256631

LAR1B
La-related protein 1B

1

15

High-throughput

0.691

High

256634

LARP1
La-related protein 1

1

16

High-throughput

0.691

High

256646

DND1
Dead end protein homolog 1

1

20

High-throughput

0.691

High

256653

LAR4B
La-related protein 4B

1

15

High-throughput

0.691

High

256664

PABP5
Polyadenylate-binding protein 5

1

10

High-throughput

0.691

High

256666

RMXL1
RNA binding motif protein, X-linked-like-1

1

20

High-throughput

0.691

High

256668

ZC3HA
Zinc finger CCCH domain-containing protein 10

1

2

High-throughput

0.691

High

256669

ZFR
Zinc finger RNA-binding protein

1

17

High-throughput

0.691

High

256679

MKRN2
E3 ubiquitin-protein ligase makorin-2

1

13

High-throughput

0.691

High

256694

DJC17
DnaJ homolog subfamily C member 17

1

3

High-throughput

0.691

High

256695

RBM22
Pre-mRNA-splicing factor RBM22

1

13

High-throughput

0.691

High

256704

PPIE
Peptidyl-prolyl cis-trans isomerase E

1

7

High-throughput

0.691

High

256630

Q53GL6
RNA binding protein

1

14

High-throughput

0.665

High

244624

ZC3H1
Zinc finger C3H1 domain-containing protein

2

1

High-throughput

0.628

High

256559

ULK1
Serine/threonine-protein kinase ULK1

1

7

High-throughput

0.618

High

256641

PIM3
Serine/threonine-protein kinase pim-3

1

5

High-throughput

0.618

High

85521

HNRC3
Heterogeneous nuclear ribonucleoprotein C-like 3

1

15

High-throughput

0.618

High

256576

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

1

Small-scale

0.618

High

256628

LARP7
La-related protein 7

1

20

High-throughput

0.618

High

256651

SREK1
Splicing regulatory glutamine/lysine-rich protein 1

1

5

Small-scale

0.618

High

256656

RBP56
TATA-binding protein-associated factor 2N

1

15

High-throughput

0.618

High

256562

PIAS2
E3 SUMO-protein ligase PIAS2

2

2

High-throughput

0.606

High

256606

RNF4
E3 ubiquitin-protein ligase RNF4

2

3

High-throughput

0.606

High

256710

ARIP4
Helicase ARIP4

2

18

High-throughput

0.606

High

256566

ANXA2
Annexin A2

2

3

High-throughput

0.584

High

256572

PAB4L
Polyadenylate-binding protein 4-like

1

10

High-throughput

0.575

High

256636

NKAP1
Uncharacterized protein NKAPD1

2

3

High-throughput

0.574

High

256558

SH3L1
Adapter SH3BGRL

2

1

High-throughput

0.571

High

256569

HCK
Tyrosine-protein kinase HCK

2

12

High-throughput

0.571

High

256622

PTK6
Protein-tyrosine kinase 6

2

12

High-throughput

0.571

High

256655

TFG
Protein TFG

2

3

High-throughput

0.558

High

256577

VINC
Vinculin

1

3

High-throughput

0.553

High

138600

IMA4
Importin subunit alpha-4

1

6

High-throughput

0.536

High

142460

IMA3
Importin subunit alpha-3

1

6

High-throughput

0.536

High

183404

CASC3
Protein CASC3

1

4

High-throughput

0.536

High

245036

AQR
RNA helicase aquarius

1

16

High-throughput

0.536

High

250952

PRP17
Pre-mRNA-processing factor 17

1

17

High-throughput

0.536

High

256556

PTCD1
Pentatricopeptide repeat-containing protein 1, mitochondrial

1

1

High-throughput

0.536

High

256557

ZC11A
Zinc finger CCCH domain-containing protein 11A

1

3

High-throughput

0.536

High

256561

PRKRA
Interferon-inducible double-stranded RNA-dependent protein kinase activator A

1

20

High-throughput

0.536

High

256575

H12
Histone H1.2

1

6

High-throughput

0.536

High

256582

H2B1O
Histone H2B type 1-O

1

3

High-throughput

0.536

High

256601

CCNH
Cyclin-H

1

1

High-throughput

0.536

High

256602

H2B1D
Histone H2B type 1-D

1

3

High-throughput

0.536

High

256611

H11
Histone H1.1

1

6

High-throughput

0.536

High

256616

SNW1
SNW domain-containing protein 1

1

5

High-throughput

0.536

High

256618

CUL1
Cullin-1

1

20

High-throughput

0.536

High

256620

CUL3
Cullin-3

1

20

High-throughput

0.536

High

256621

CUL4B
Cullin-4B

1

20

High-throughput

0.536

High

256626

HNRL2
Heterogeneous nuclear ribonucleoprotein U-like protein 2

1

8

High-throughput

0.536

High

256629

NCBP3
Nuclear cap-binding protein subunit 3

1

3

High-throughput

0.536

High

256633

ZC3HE
Zinc finger CCCH domain-containing protein 14

1

3

High-throughput

0.536

High

256635

NHLC1
E3 ubiquitin-protein ligase NHLRC1

1

2

High-throughput

0.536

High

256640

MTA70
N(6)-adenosine-methyltransferase catalytic subunit METTL3

1

3

High-throughput

0.536

High

256642

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

9

High-throughput

0.536

High

256645

SUV3
ATP-dependent RNA helicase SUPV3L1, mitochondrial

1

2

High-throughput

0.536

High

256647

PR38A
Pre-mRNA-splicing factor 38A

1

1

High-throughput

0.536

High

256648

PPHLN
Periphilin-1

1

2

High-throughput

0.536

High

256649

PUM2
Pumilio homolog 2

1

7

High-throughput

0.536

High

256657

RENT1
Regulator of nonsense transcripts 1

1

12

High-throughput

0.536

High

256658

CSN5
COP9 signalosome complex subunit 5

1

4

High-throughput

0.536

High

256659

CUL5
Cullin-5

1

20

High-throughput

0.536

High

256663

ESS2
Splicing factor ESS-2 homolog

1

3

High-throughput

0.536

High

256670

YTDC1
YTH domain-containing protein 1

1

9

High-throughput

0.536

High

256671

QKI
KH domain-containing RNA-binding protein QKI

1

17

High-throughput

0.536

High

256672

UIF
UAP56-interacting factor

1

2

High-throughput

0.536

High

256676

RM13
Large ribosomal subunit protein uL13m

1

1

High-throughput

0.536

High

256677

CRNL1
Crooked neck-like protein 1

1

17

High-throughput

0.536

High

256680

PAIP1
Polyadenylate-binding protein-interacting protein 1

1

4

High-throughput

0.536

High

256682

P63
Tumor protein 63

1

3

Small-scale

0.536

High

256684

SFR19
Splicing factor, arginine/serine-rich 19

1

9

High-throughput

0.536

High

256685

PHAX
Phosphorylated adapter RNA export protein

1

2

High-throughput

0.536

High

256686

MOV10
Helicase MOV-10

1

12

High-throughput

0.536

High

256688

SYF1
Pre-mRNA-splicing factor SYF1

1

18

High-throughput

0.536

High

256690

NGRN
Neugrin

1

2

High-throughput

0.536

High

256692

ZCHC3
Zinc finger CCHC domain-containing protein 3

1

4

High-throughput

0.536

High

256693

STAU2
Double-stranded RNA-binding protein Staufen homolog 2

1

20

High-throughput

0.536

High

256696

BCLF1
Bcl-2-associated transcription factor 1

1

5

High-throughput

0.536

High

256697

F120A
Constitutive coactivator of PPAR-gamma-like protein 1

1

5

High-throughput

0.536

High

256699

MKRN1
E3 ubiquitin-protein ligase makorin-1

1

12

High-throughput

0.536

High

256702

ISY1
Pre-mRNA-splicing factor ISY1 homolog

1

3

High-throughput

0.536

High

256708

TR150
Thyroid hormone receptor-associated protein 3

1

7

High-throughput

0.536

High

256711

HEY1
Hairy/enhancer-of-split related with YRPW motif protein 1

1

3

High-throughput

0.536

High

256568

YES
Tyrosine-protein kinase Yes

2

12

High-throughput

0.521

High

256571

FGR
Tyrosine-protein kinase Fgr

2

12

High-throughput

0.521

High

256579

RAB5A
Ras-related protein Rab-5A

2

3

High-throughput

0.521

High

256598

BLK
Tyrosine-protein kinase Blk

2

12

High-throughput

0.521

High

256581

XPA
DNA repair protein complementing XP-A cells

1

0

High-throughput

0.513

High

256586

GLYC
Serine hydroxymethyltransferase, cytosolic

1

0

High-throughput

0.513

High

256624

FL2D
Pre-mRNA-splicing regulator WTAP

1

0

High-throughput

0.513

High

256709

SYYM
Tyrosine--tRNA ligase, mitochondrial

1

0

High-throughput

0.513

High

256573

RAC2
Ras-related C3 botulinum toxin substrate 2

1

2

High-throughput

0.489

High

256584

PRDX3
Thioredoxin-dependent peroxide reductase, mitochondrial

1

1

High-throughput

0.489

High

256619

CUL2
Cullin-2

1

20

High-throughput

0.489

High

256627

C19L2
CWF19-like protein 2

1

6

High-throughput

0.489

High

256632

CP135
Centrosomal protein of 135 kDa

1

7

High-throughput

0.489

High

256650

CCD12
Coiled-coil domain-containing protein 12

1

2

High-throughput

0.489

High

256665

MTEF3
Transcription termination factor 3, mitochondrial

1

2

High-throughput

0.489

High

256691

TRPV5
Transient receptor potential cation channel subfamily V member 5

1

1

High-throughput

0.489

High

256703

PAI2B
Polyadenylate-binding protein-interacting protein 2B

1

1

High-throughput

0.489

High

256604

UBC9
SUMO-conjugating enzyme UBC9

1

6

High-throughput

0.481

High

176913

CE290
Centrosomal protein of 290 kDa

1

18

High-throughput

0.479

High

240243

PRKN
E3 ubiquitin-protein ligase parkin

1

18

High-throughput

0.479

High

256563

HEXI1
Protein HEXIM1

1

3

High-throughput

0.479

High

256564

ARI2
E3 ubiquitin-protein ligase ARIH2

1

15

High-throughput

0.479

High

256574

RFA2
Replication protein A 32 kDa subunit

1

7

High-throughput

0.479

High

256583

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

5

High-throughput

0.479

High

256585

MCM5
DNA replication licensing factor MCM5

1

4

High-throughput

0.479

High

256591

RS19
Small ribosomal subunit protein eS19

1

3

High-throughput

0.479

High

256592

MATR3
Matrin-3

1

20

High-throughput

0.479

High

256593

YAP1
Transcriptional coactivator YAP1

1

14

High-throughput

0.479

High

256594

FAS
Fatty acid synthase

1

3

High-throughput

0.479

High

256599

MECP2
Methyl-CpG-binding protein 2

1

9

High-throughput

0.479

High

256603

1433G
14-3-3 protein gamma

1

20

High-throughput

0.479

High

256610

HSF1
Heat shock factor protein 1

1

1

High-throughput

0.479

High

256613

TFCP2
Alpha-globin transcription factor CP2

1

4

High-throughput

0.479

High

256638

MEPCE
7SK snRNA methylphosphate capping enzyme

1

3

High-throughput

0.479

High

256644

SMC5
Structural maintenance of chromosomes protein 5

1

6

High-throughput

0.479

High

256660

RL36L
Ribosomal protein eL42-like

1

3

High-throughput

0.479

High

256673

CRBN
Protein cereblon

1

1

Small-scale

0.479

High

256675

FACD2
Fanconi anemia group D2 protein

1

9

High-throughput

0.479

High

256705

VDAC3
Non-selective voltage-gated ion channel VDAC3

1

6

High-throughput

0.479

High

256706

ASF1A
Histone chaperone ASF1A

1

1

High-throughput

0.479

High

256637

Q7KZS0
SUMO-conjugating enzyme UBC9

1

6

High-throughput

0.470

High

256698

WWOX
WW domain-containing oxidoreductase

1

0

High-throughput

0.458

High

256565

JUN
Transcription factor Jun

1

12

High-throughput

0.445

High

256587

BMI1
Polycomb complex protein BMI-1

1

12

High-throughput

0.445

High

256590

RL4
Large ribosomal subunit protein uL4

1

2

High-throughput

0.445

High

256654

ESR2
Estrogen receptor beta

1

17

High-throughput

0.445

High

256700

DDX41
Probable ATP-dependent RNA helicase DDX41

1

12

High-throughput

0.445

High

213541

VIP2
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2

1

3

High-throughput

0.437

High

256555

PLXA2
Plexin-A2

1

8

High-throughput

0.437

High

256588

RFA3
Replication protein A 14 kDa subunit

1

5

High-throughput

0.437

High

256625

TNIP1
TNFAIP3-interacting protein 1

1

20

High-throughput

0.437

High

256662

CHM4C
Charged multivesicular body protein 4c

1

7

High-throughput

0.437

High

256687

PLXA4
Plexin-A4

1

7

High-throughput

0.437

High

256707

UBP20
Ubiquitin carboxyl-terminal hydrolase 20

1

5

Small-scale

0.437

High

256600

GPC3
Glypican-3

1

2

High-throughput

0.407

High

256678

MLP3B
Microtubule-associated protein 1 light chain 3 beta

1

12

High-throughput

0.407

High

256683

MLP3A
Microtubule-associated protein 1 light chain 3 alpha

1

12

High-throughput

0.407

High

50776

CT202
Uncharacterized protein C20orf202

2

0

High-throughput

0.316

High

256597

GBG10

1

0

High-throughput

0.279

Low

256609

PRR5
Proline-rich protein 5

1

0

High-throughput

0.279

Low

256652

SIA8B
Alpha-2,8-sialyltransferase 8B

1

0

High-throughput

0.279

Low

256661

TR19L
Tumor necrosis factor receptor superfamily member 19L

1

0

High-throughput

0.279

Low

256667

HMCES
Abasic site processing protein HMCES

1

0

High-throughput

0.279

Low

256674

F118B
Protein FAM118B

1

0

High-throughput

0.279

Low

256689

BPIA1
BPI fold-containing family A member 1

1

0

High-throughput

0.279

Low

256643

SULF2
Extracellular sulfatase Sulf-2

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025