Interactor 1: RPOB (P0A8V2)
DNA-directed RNA polymerase subunit beta (RNAP subunit beta) (EC 2.7.7.6) (RNA polymerase subunit beta) (Transcriptase subunit beta)
Gene: RPOB

Interactor 2: FLIA (P0AEM6)
RNA polymerase sigma factor FliA (RNA polymerase sigma factor for flagellar operon) (Sigma F) (Sigma-27) (Sigma-28)
Gene: FLIA

Species: Escherichia coli K-12

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 16606699
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains RNA_pol_Rpb2_1~Sigma70_r2, RNA_pol_Rpb2_1~Sigma70_r3, RNA_pol_Rpb2_6~Sigma70_r2, RNA_pol_Rpb2_6~Sigma70_r3, RNA_pol_Rpb2_6~Sigma70_r4, RNA_pol_Rpb2_7~Sigma70_r2, RNA_pol_Rpb2_7~Sigma70_r3
Common GO terms GO:0000345 - cytosolic DNA-directed RNA polymerase complex
GO:0003677 - DNA binding
GO:0003899 - DNA-directed 5'-3' RNA polymerase activity
GO:0005829 - cytosol
GO:0006352 - DNA-templated transcription initiation
and 3 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 1342
Ec

1 239
+ Ec
+ Ec
+ Ec
+ Nv
+ Hp
+ Hp
+ Mp
+ Ss
+ Ss
+ Ss
+ Bs
+ Bs

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Last updated: 15 Jul 2024