HitPredict

Interactor 1: DPO3B (P0A988)
Beta sliding clamp (Beta clamp) (Sliding clamp) (Beta-clamp processivity factor) (DNA polymerase III beta sliding clamp subunit)
Gene: dnaN

Interactor 2: DPO3A (P10443)
DNA polymerase III subunit alpha (EC 2.7.7.7)
Gene: dnaE

Species: Escherichia coli K-12

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.86	1.00	0.928

Property	Details
Experiments	24561554, 19402753, 23435564, 23549287, 2040637
Identification Methods	two hybrid, tandem affinity purification, mass spectrometry studies of complexes, molecular sieving, cross-linking study, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	DNA_pol3_beta~tRNA_anti-codon, DNA_pol3_beta_3~tRNA_anti-codon
Common GO terms	GO:0003677 - DNA binding GO:0003887 - DNA-directed DNA polymerase activity GO:0005829 - cytosol GO:0006261 - DNA-templated DNA replication GO:0009360 - DNA polymerase III complex and 1 others more... GO:0030894 - replisome
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 366 Ec			1 1160
+	Mt
		958647 DPO3B_MYCTU (1-366): 3.45e-130: 380: 27.48		DPO3A_MYCTU (2-1151): 0: 1391: 35.40
+	Ms
		49507 DPO3B_MYCS2 (1-366): 2.42e-129: 377: 27.18		A0QX55_MYCS2 (2-1151): 0: 1370: 35.29
+	Mt
		958646 DPO3B_MYCTU (1-366): 3.45e-130: 380: 27.48		DNAE2_MYCTU (2-1070): 0: 1095: 30.77
+	Bs
		404200 DPO3B_BACSU (1-365): 1.2e-119: 352: 26.26		DPO3_BACSU (80-899): 0: 647: 21.44